Introduction
Mozambique has a high burden of Tuberculosis (TB) with an incidence of 368 per 100,000 population in 2020, coupled with a low all-form TB detection rate. The COVID-19 pandemic has exacerbated delays in timely diagnosis and treatment of new TB cases. Promoting active TB case finding is a nati...
Cervera, Belén Saavedra;
López, Mariana G;
Chiner-Oms, Álvaro;
García, Ana Maria;
Cancino-Muñoz, Irving;
Torres-Puente, Manuela;
Villamayor, Luis;
Carlos Madrazo-Moya, Carlos;
Mambuque, Edson;
Sequera, Guilherme Victor;
Respeito, Durval;
Blanco, Sílvia;
Augusto, Orvalho;
López-Varela, Elisa;
Garcia-Basteiro, Alberto L;
Comas, Iñaki.
Genomic studies of the Mycobacterium tuberculosis complex (MTBC) might shed light on the dynamics of its transmission, especially in high-burden settings, where recent outbreaks are embedded in the complex natural history of the disease. To this end, we conducted a 1 year prospective surveillance-based ...
Manhiça, Ivan;
Augusto, Orvalho;
Sherr, Kenneth;
Cowan, James;
Cuco, Rosa Marlene;
Agostinho, Sãozinha;
Macuacua, Bachir C;
Carimo, Naziat;
Matsinhe, Maria Benigna;
Gloyd, Stephen;
Chicumbe, Sergio;
Machava, Raimundo;
Tembe, Stélio;
Fernandes, Quinhas;
Ramiro, Isaías.
Introduction Currently, COVID- 19 dominates the public health agenda and poses a permanent threat, leading to health systems’ exhaustion and unprecedented service disruption. Primary healthcare services, including tuberculosis services, are at increased risk of facing severe disruptions, particularly i...
Martin-Hughes, Rowan;
Vu, Lung;
Cheikh, Nejma;
Kelly, Sherrie L;
Hur, Nicole Fraser;
Shubber, Zara;
Manhiça, Ivan;
Mbendera, Kuzani;
Girma, Belaineh;
Pambudi, mran;
Ríos, Julia;
Elmira, Abdrahmanova;
Harimurti, Pandu;
Hafez, Reem;
Garcia, Jaime Nicolas Bayona;
Palmer, Tom;
Roberts, Anna;
Gorgens, Marelize;
Wilson, David.
Initial global-level estimates reported in June 2020 by the World Health Organization suggested that levels of disruption to TB service delivery could be as high as 25%-50% and result in an additional 6·3 million cases of tuberculosis (TB) and an additional 1·4 million TB-related deaths attributable to...
Izco, Santiago;
Murias-Closas, Adrià;
Jordan, Alexander M;
Greene, Gregory;
Catorze, Nteruma;
Chiconela, Helio;
Garcia, Juan Ignacio;
Blanco-Arevalo, Alejandro;
Febrer, Anna;
Casellas, Aina;
Saavedra, Belén;
Chiller, Tom;
Nhampossa, Tacilta;
Garcia-Basteiro, Alberto;
Letang, Emilio.
Introduction: AIDS-mortality remains unacceptably high in sub-Saharan Africa, largely driven by advanced HIV disease (AHD). We nested a study in an existing tuberculosis (TB) contact-tracing intervention (Xpatial-TB). The aim was to assess the burden of AHD among high-risk people living with HIV (PLHIV) ...
Background Mozambique is one of the countries with the deadly implementation gaps in the tuberculosis (TB) care and services delivery. In-hospital delays in TB diagnosis and treatment, transmission and mortality still persist, in part, due to poor-quality of TB care cascade. Objective We aimed to assess,...
Tuberculosis (TB) continues to be a leading cause of death in Sub-Saharan Africa, including Mozambique. While diagnostic methods and total notifications are improving, significant gaps remain between total numbers of TB cases annually, and the number that are notified. The purpose of this study was to el...
Tuberculose/epidemiologia,
Causas de Morte,
Conscientização,
Diagnóstico,
Tuberculose/mortalidade,
Terapêutica,
Tutoria,
Tuberculose/microbiologia,
Moçambique,
Tuberculose Extensivamente Resistente a Medicamentos,
Tuberculose Extensivamente Resistente a Medicamentos/tratamento farmacológico,
HIV,
Infecções por HIV/terapia
Orlando, s;
Triulzi, i;
Ciccacci, f;
Palla, i;
Palombi, l;
Marazzi, m c;
Giuliano, m;
Floridia, m;
Mancinelli, s;
Mutemba, e;
Turchetti, g.
Background: Tuberculosis (TB) represents the ninth leading cause of death worldwide. In 2016 are estimated 1.3 million TB deaths among HIV negative people and an additional 374,000 deaths among HIV positive people. In 2016 are estimated 1.4 million new cases of TB in people living with HIV (PLHIV), 74% o...
Comorbidade,
Análise Custo-Benefício,
Diagnóstico Tardio,
Testes Diagnósticos de Rotina/métodos,
Infecções por HIV/diagnóstico,
Infecções por HIV/epidemiologia,
Infecções por HIV/terapia,
Programas de Rastreamento/métodos,
Reprodutibilidade dos Testes,
Tuberculose/epidemiologia,
Tuberculose/diagnóstico,
Tuberculose/terapia,
Moçambique/epidemiologia,
Ensaios de Triagem em Larga Escala/economia,
Moçambique
Background
Studies have been conducted in developing countries using SMS to communicate with patients to reduce the number of missed appointments and improve retention in treatment, however; very few have been scaled up. One possible reason for this could be that patients or staff are dissatisfied with t...
Tuberculosis (TB) remains an important public health concern and a leading cause of disease and death worldwide. Mozambique is one of the few high-burden countries where incidence rates have not improved in recent years. The estimated TB incidence rate in 2014 was 552 cases per 100 000 population and t...
