Perfil de sensibilidade dos isolados de Mycobacterium tuberculosis de pacientes com tuberculose e coinfectados TB/HIV na cidade da Beira, Sofala, Moçambique

Ano de publicação: 2016
Teses e dissertações em Português apresentado à Universidade de são Paulo faculdade de medicina de ribeirão preto para obtenção do título de Doutor. Orientador: Valdes Roberto Bollela

A tuberculose (TB) é uma doença infecciosa que ameaça a humanidade há séculos. Recentemente grandes avanços foram conseguidos no combate à tuberculose, entretanto a resistência bacilar e a coinfecção pelo Vírus de Imunodeficiência Humana (HIV) persistem como os principais desafios dos programas de combate à tuberculose globalmente e também em Moçambique.O objetivo deste trabalho foi estimar a prevalência e caracterizar o perfil genotípico da resistência do bacilo da tuberculose às drogas de primeira e segunda linha do tratamento da TB. Foi realizado um estudo descritivo com 155 isolados correspondentes ao mesmo número de pacientes,obtidos no Hospital Central da Beira-­Moçambique em 2014 e 2015.
Tuberculosis (TB) is an infectious disease that has threatened humanity for centuries. Recently large advances have been made in the fight against tuberculosis, however bacillary resistance and coinfection by Human Immunodeficiency Virus (HIV) persist as the main challenges of programs to combat tuberculosis globally and also in Mozambique. The objective of this work was to estimate the prevalence and to characterize the genotypic profile of the resistance of the tuberculosis bacillus to the first and second line drugs of TB treatment. A descriptive study was carried out with 155 corresponding to the same number of patients, obtained at the Central Hospital of Beira-Mozambique in 2014 and 2015. Tuberculosis (TB) is an infectious disease that has threatened humanity for centuries. Recently large advances have been made in the fight against tuberculosis, however bacillary resistance and coinfection by Human Immunodeficiency Virus (HIV) persist as the main challenges of programs to combat tuberculosis globally and also in Mozambique. The objective of this work was to estimate the prevalence and to characterize the genotypic profile of the resistance of the tuberculosis bacillus to the first and second line drugs of TB treatment. A descriptive study was carried out with 155 concessions corresponding to the same number of patients, obtained at the Central Hospital of Beira-Mozambique in 2014 and 2015.

Mais relacionados