Background:Tropical idiopathic lower limb gangrene (TILLG) is also known as Symmetrical gangrene in the African; Idiopathic gangrene in the African and Idiopathic peripheral gangrene of the tropics.The aetiopathogenesis of this clinical entity is a mystery. Objective: To review methods of diagnosing trop...
Background: Fetal hemoglobin has been implicated in the modulation of sickle cell crisis though it is functional during infancy. Objective:The purpose of this study was to determine the waning time of fetal hemoglobin (HbF) and its persistence in later life. Method: Ninety infants aged 0-12 months; admit...
Background: Neurologic infections are an important cause of morbidity and mortality especially worldwide but much more in the African continent.The frequency of the different types of neurologic infections and their mortality in this part of Nigeria is not known. Objectives: To review cases admitted into...
Background: Medical establishment such as hospitals and research institutes generate sizable amount of hazardous waste. Health care workers; patients are at risk of acquiring infection from sharps and contamination of environment with multiple drug resistant microorganisms if wastes are not properly mana...
Background: Neonatal sepsis is a significant cause of neonatal mortality in developing countries. The aetiological agents and their antimicrobial susceptibility patterns are dynamic.Objectives: This study determined clinical features, aetiology, antimicrobial susceptibility and clinical outcome of neonat...
Introduction: We report on the first documented cluster of Coronavirus Disease 2019 cases amongst diagnostic laboratory staff and outline some of the initial and ongoing steps that are being implemented to manage and prevent the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in ou...
Background: Childhood brucellosis and malaria are co-endemic febrile illnesses in some sub-Saharan African countries. Malaria and brucellosis co-infection or brucellosis sole infections are often missed due to an over emphasis on malaria and the lack of appropriate diagnostic infrastructure. Brucellosis ...
Background: Outpatient sampling is used to investigate endometrial pathology. Little is known about practice habits and local failure rates at Chris Hani Baragwanath Academic Hospital in Johannesburg, South Africa.Objective: This study assessed the frequency of samples that showed no or limited histologi...
Background: Proficiency testing (PT) is part of a comprehensive quality assurance programme, which is critical to ensuring patients receive accurate and reliable diagnostic testing. Implementation of the Cepheid Xpert® MTB/RIF assay to aid in the diagnosis of tuberculosis has expanded rapidly in recent ...
Background: Prostate cancer (PCa) is a leading male neoplasm in South Africa.Objective: The aim of our study was to describe PCa using Systemized Nomenclature of Medicine (SNOMED) clinical terms codes, which have the potential to generate more timely data.Methods: The retrospective study design was used ...
