Cross-border human population movement contributes to malaria transmission in border regions, impeding national elimination. However, its impact in low-to-moderate transmission settings is not well characterized. This community-based study in Mutasa District, Zimbabwe, estimated the association of parasi...
Matambisso, Glória;
Brokhattingen, Nanna;
Maculuve, Sónia;
Cístero, Pau;
Mbeve, Henriques;
Escoda, Anna;
Bambo, Gizela;
Cuna, Boaventura;
Melembe, Cardoso;
Ndimande, Nelo;
Tetteh, Kevin K. A;
Drakeley, Chris;
Gamain, Benoit;
Chitnis, Chetan;
Chauhan, Virander;
Quintó, Llorenç;
Macete, Eusébio;
Mayor, Alfredo.
Objective: The effectiveness of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) is threatened by increasing SP-resistance in Africa. We assessed the level of SP-resistance markers, and the clinical and parasitological effectiveness of IPTp-SP in southern...
Pyrimethamine,
Malaria, Falciparum,
Drug Resistance,
Chemoprevention/methods,
Antimalarials/therapeutic use,
Sulfadoxine,
Antineoplastic Combined Chemotherapy Protocols,
Pregnancy Complications, Parasitic/therapy,
Pregnancy Complications, Parasitic/prevention & control,
Mozambique/epidemiology
epidemiological estimates from the 2021 Joint United Nations Program on HIV/AIDS (UNAIDS) emphasize the existing gender disparities, where women face a higher risk of HIV/AIDS exposure. In Mozambique, as of 2021, the HIV prevalence rate among the adult population stood at 12.5%, with an even more concern...
Henriques, Viola;
Bi, Angela;
Khosa, Dalva;
Mateus, Zacarias;
da Rocha, Massada;
Amado, Vand;
Taela, Atanásio;
DeUgarte, Daniel A;
Schindele, Andreas;
Buck, W. Chris.
To close diagnostic gaps for children living with HIV, the World Health Organization (WHO) recommends routine opt-out provider-initiated testing and counselling (PITC) for inpatient wards in high-prevalence countries, which includes nucleic acid testing as part of Early Infant Diagnosis (EID) programmes ...
O primeiro caso de SIDA em Moçambique foi diagnosticado em 1986.1 Em 2024,
cerca de 2,4 milhões de moçambicanos estão a viver com o HIV.2 Em resposta à
recomendação da Organização Mundial da Saúde de criação de comités nacio
nais de luta contra o SIDA,3,4 em Agosto de 1986 foi criada a Com...
Langa, Judite;
Deus, Maria Inês de Deus;
Arciniegas, Sarah;
Wate, Argentina;
Bila, Erica;
Alfândega, Arla;
Mate, Nelice;
Rungo, Irene;
Azambuja, Gizela;
Tibana, Kwalila;
Eliseu, Námita.
Moçambique implementa a Prevenção da Transmissão Vertical (PTV) do HIV como parte do Programa Nacional desde 2002. Apesar dos ganhos, a taxa de transmissão vertical continua elevada, estimada em 9% em 2023. Descrevemos o progresso da PTV nas Unidades Sanitárias (US) apoidas pelo PEPFAR.
Métodos: A...
Chisenga, Mukosha;
Dlamini, Bongani;
Mwendera, Nyasha;
Maquina, Paulo;
Hamainza, Busiku;
Martins, José Franco;
Saute, Francisco;
Bock, Henrico;
Gosling, Roly;
Bennett, Adam;
Smith, Jennifer;
Kleinschmidt, Immo.
Background The importation of parasites across borders remains a threat to malaria elimination. The Southern African Development Community Malaria Elimination Eight (E8) established 39 border health facilities on 5 key international borders between high and low-burden countries. These clinics aimed to im...
The investment in health services in low- and middle-income countries has increased substantially in recent years.1 Such investment has been led by unprecedented efforts to combat major diseases, enabled by the availability of lower-cost and effective drug regimens for treatment and prophylaxis, along wi...
Background: Plasmodium falciparum infection in pregnant women in sub-Saharan Africa is often asymptomatic. As these forms of malaria are often submicroscopic and difficult to diagnose by conventional methods (microscopy and/or rapid diagnostic test), diagnosis requires the use of molecular techniques suc...
Castilho, Paula Ruiz;
Imputiua, Saimado;
Xie, Kexin;
Elobolobo, Eldo;
Nicolas, Patricia;
Montana, Julia;
Jamisse, Edgar;
Munguambe, Humberto;
Materrula, Felisbela;
Casellas, Aina;
Deng, Xinwei;
Marathe, Achla;
Rabinovich, Regina;
Saute, Francisco;
Chaccour, Carlos;
Sacoor, Charfudin.
Many geographical areas of sub-Saharan Africa, especially in rural settings, lack complete and up-to-date demographic data, posing a challenge for implementation and evaluation of public health interventions and carrying out large-scale health research. A demographic survey was completed in Mopeia distri...
