Total: 6404

Boletim epidemiológico: situação epidemiológica de HIV e aids em adultos no estado de Goiás, 2020 a 2024
Epidemiological bulletin: epidemiological situation of HIV and AIDS in adults in the state of Goiás, 2020 to 2024

Boletim epidemiológico que apresenta informações sobre os casos de HIV no estado de Goiás e tem como objetivo descrever o perfil epidemiológico, tendências da infecção na população adulta entre os anos 2020 a 2024 e fornecer subsídios para a tomada de decisão, medidas de vigilância, prevenç...

Modelling protein-protein interactions for the design of vaccine chimeric antigens with protective epitopes

PLos ONE; 20 (2), 2025
Ticks and tick-borne diseases are a growing burden worldwide and vaccines are effective control interventions. Vaccine formulations with tick antigens such as BM86/BM95 (BM) and Subolesin (SUB) have shown reduction in tick fitness and infestation in immunized hosts. However, antigen combination is a chal...

Development and validation of a checklist for cardiopulmonary bypass

J. extra-corpor. technol; 57 (1), 2025
INTRODUCTION: Risk prevention protocols related to patient care have been developed to reduce the incidence of adverse events in health care services. Cardiopulmonary bypass (CPB) can trigger several complications, including physiological problems, electrical, mechanical, and human failures, or defective...

Sacubitril-Valsartan lowers atrial fibrillation recurrence and left atrial volume post-catheter ablation: systematic review and meta-analysis

Am. j. cardiovasc. drugs; 25 (2), 2025
INTRODUCTION: In patients with atrial fibrillation (AF) who have undergone catheter ablation, the comparative effectiveness of sacubitril-valsartan (SV) versus ACE inhibitors (ACEi) or angiotensin-receptor blockers (ARB) in preventing AF recurrence remains unclear. The purpose of the present systematic r...

Painful left bundle branch Block Syndrome: a systematic review of treatment strategies in case reports

BACKGROUND Painful left bundle branch block (PLBBB) syndrome remains a poorly understood cardiac anomaly. This systematic review consolidates case report evidence to elucidate effective management strategies and patient outcomes. METHODS Databases including PubMed, Scopus, Web of Science, and Scielo were...

Protocolo de Vigilância em Saúde e Manejo Clínico para Brucelose Humana no Tocantins
Health Surveillance and Clinical Management Protocol for Human

A brucelose humana é uma zoonose bacteriana de relevância global. Este protocolo apresenta diretrizes para a vigilância epidemiológica e manejo clínico da brucelose humana no estado do Tocantins. O documento aborda as formas de transmissão, diagnóstico laboratorial, tratamento e medidas de control...

“Smart” analysis of the landmark trial - early outcomes with latest generation tavi valves in patients with a small aortic annulus

JACC cardiovasc. interv; 18 (4 Suppl. S), 2025
BACKGROUND Among patients with severe aortic stenosis (AS) un- dergoing transcatheter aortic valve implantation (TAVI), nearly one third have a small aortic annulus. These patients are at higher risk of prosthetic valve dysfunction. Recently, the SMART trial reported that the self-expanding Evolut series...

Penetrance of TAVR in latin america compared with north america and europe - insight from biba medtech registry

JACC cardiovasc. interv; 18 (4 Suppl. S), 2025
BACKGROUND Since its commercialization in 2007, the number of transcatheter aortic valve replacement (TAVR) procedures has grown exponentially worldwide. The penetrance of TAVR in Latin America compared to North America and Europe, remains unknown. We sought to examine the penetrance of TAVR in Latin Ame...

Integrative analysis of miRNAs and proteins in plasma extracellular vesicles of patients with familial hypercholesterolemia

Clin Chim Acta; 568 (), 2025
BACKGROUND AND AIMS: Familial Hypercholesterolemia (FH) is a monogenic disease that leads to early-onset atherosclerosis. Causative mutations in FH-related genes are found in 60-80 % of patients, while epigenetic factors may contribute to mutation-negative cases. This study analyzed miRNAs and proteins f...

Combined left atrial appendage occlusion and catheter ablation for atrial fibrillation versus isolated left atrial appendage occlusion: A systematic review and meta-analysis

Int. j. cardiol; 421 (), 2025
BACKGROUND: Data on the effects of combined left atrial appendage occlusion (LAAO) and catheter ablation (CA) for atrial fibrillation (AF) remain limited. We aimed to perform a systematic review and meta-analysis comparing LAAO and CA versus isolated LAAO. METHODS: We systematically searched PubMed, Emba...