PURPOSE: The involvement of the circulating endothelium-derived microparticles (EMPs) and the endothelial progenitor cells (EPCs) has been shown in the pathogenesis of coronary artery disease (CAD). The current study aimed to explore whether the Friesinger index is associated with the levels of the apopt...
Borges, Jéssica Bassani;
Oliveira, Victor Fernandes de;
Ferreira, Glaucio Monteiro;
Los, Bruna;
Barbosa, Thais Kristini Almendros Afonso;
Marçal, Elisangela da Silva Rodrigues;
Dagli-Hernandez, Carolina;
Freitas, Renata Caroline Costa de;
Bortolin, Raul Hernandes;
Mori, Augusto Akira;
Hirata, Thiago Dominguez Crespo;
Nakaya, Helder Takashi Imoto;
Bastos, Gisele Medeiros;
Thurow, Helena Strelow;
Gonçalves, Rodrigo Marques;
Araujo, Daniel Branco de;
Zatz, Henry Paulo;
Bertolami, Adriana;
Faludi, André Arpad;
Bertolami, Marcelo Chiara;
Sousa, Amanda Guerra de Moraes Rego;
França, João Ítalo Dias;
Jannes, Cinthia Elim;
Pereira, Alexandre da Costa;
Nakazone, Marcelo Arruda;
Souza, Dorotéia Rossi Silva;
Carmo, Tayanne Silva;
Sampaiol, Marcelo Ferraz;
Gorjao, Renata;
Pithon-Curi, Tania Cristina;
Moriel, Patricia;
Silbiger, Vivian Nogueira;
Luchessi, André Ducati;
Araújo, Jéssica Nayara Góes de;
Naslavsky, Michel Satya;
Yu Ting Wang, Jaqueline;
Kronenberger, Thales;
Cerda, Alvaro;
Lin-Wang, Hui Tzu;
Garofalo, Adriana Regina;
Fajardo, Cristina Moreno;
Hirata, Rosario Dominguez Crespo;
Hirata, Mario Hiroyuki.
BACKGROUND: Familial hypercholesterolemia (FH) is a genetic disease that affects millions of people worldwide. OBJECTIVES: The study protocol FHBGEP was design to investigate the main genomic, epigenomic, and pharmacogenomic factors associated with FH and polygenic hypercholesterolemia (PH). METHODS: FH ...
BACKGROUND The primary objective of the FANTOM II Long Lesion study was to evaluate the safety and performance of native coronary artery stenting of lesions 20 mm in length using 1 or more Fantom sirolimus-eluting bioresorbable coronary scaffolds. Fantom is a fully resorbable scaffold, manufactured from...
Mehran, R;
Kandzari, D. E;
Kirtane, A. J;
Price, M. J;
Simon, D. I;
Latib, A;
Kedhi, E;
Abizaid, A;
Zaman, A;
Parke, M;
Lung, T. H;
Stone, G. W;
Windecker, S.
BACKGROUND: While dual antiplatelet therapy (DAPT) constitutes the cornerstone of post-PCI pharmacotherapy, duration of DAPT in high bleeding risk (HBR) patients has not been fully defined especially with regard to sex. The results from the Onyx ONE Clear trial demonstrated favorable safety and efficacy ...
INTRODUÇÃO: As anomalias coronárias congênitas são raras na população geral, com uma prevalência de 0,2 a 2,3%. Nos pacientes adultos a variante anatômica mais frequente é a artéria circunflexa (CX) anômala, tendo como possíveis origens o óstio separado dentro do seio coronário direito ou ...
Suárez U, Luis Rafael;
Valente, Barbara Porto;
Lijeron, Ismar Junior Peinado;
Menezes, Marília Prudente;
Santamaría N, Gabriela;
Nunes, Murilo Meneses;
Paredes H, Iván;
Uint, Luciana;
Del Mônaco, Maria Isabel;
Pavanello, Ricardo.
INTRODUÇÃO: Os aneurismas de artéria coronária (AAC) são definidos por uma dilatação focal de mais de uma vez e meia o segmento normal da artéria. São raros, sendo o aneurisma de tronco de coronária esquerda (TCE), ainda mais raro com incidência estimada em 0,1% dentre os pacientes submetidos ...
Pereira, Franc Jorge Sampaio Santos;
Menezes, Marília P;
Naranjo, Gabriela C. S;
Amato, Vívian L;
Tanajura, Luiz Fernando L;
Timerman, Ari;
C. Junior, José Ribamar;
Issa, Mário;
Feres, Fausto;
Farsky, Pedro S.
INTRODUÇÃO: Novos fármacos e procedimentos percutâneos têm modificado a evolução da doença aterosclerótica coronariana. Estudos recentes demonstraram importantes modificações nas estratégias terapêuticas. Durante a pandemia de Covid-19 houve uma significativa redução dos procedimentos cir�...
Chamié, Daniel;
Costa Jr, J. Ribamar;
Damiani, Lucas P;
Siqueira, Dimytri;
Braga, Sérgio;
Costa, Ricardo;
Seligman, Henry;
Brito, Freddy;
Barreto, Guilherme;
Staico, Rodolfo;
Feres, Fausto;
Petraco, Ricardo;
Abizaid, Alexandre.
BACKGROUND: Specific algorithms for use of optical coherence tomography (OCT) to guide percutaneous coronary intervention (PCI) are scarce. Also, the relative benefits of intravascular imaging guidance have not been tested against an optimized angiography-guided PCI strategy. In iSIGHT (Optical Coherence...
Farsky, Pedro Silvio;
Feriani, Diego;
Valente, Barbara B P;
Andrade, Maria A G;
Amato, Vivian L;
Carvalho, Larissa;
Ibanes, Aline S;
Godoy, Luiz F;
Arnoni, Renato T;
Abboud, Cely S.
COVID-19 caused by the novel coronavirus SARS-CoV-2 led to the pandemic, causing unprecedented health and social crisis worldwide. Acute coronary syndromes patients, especially when coronary artery bypass graft (CABG) surgery is needed, may present with higher severity risk if affected by COVID-19. Extra...
Objectives: Optimal medical therapy in patients with heart failure and coronary artery disease is associated with improved outcomes. However, whether this association is influenced by the performance of coronary artery bypass grafting is less well established. Thus, the aim of this study was to determine...
