Resultados: 19

Bevacizumab-induced hypertension in patients with glioblastoma: a systematic review and meta-analysis

Eur. heart j; 45 (Suppl. 1), 2024
BACKGROUND: Bevacizumab is a monoclonal antibody medication used as standard treatment for different types of cancers, one of them is glioblastoma, which is the most common primary brain tumor. PURPOSE: We aimed to assess bevacizumab and its effects on inducing hypertension in patients with glioblastoma....

Nova opção no tratamento percutâneo da cardiomiopatia hipertrófica obstrutiva
New option in the percutaneous treatment of obstructive hypertrophic cardiomyopathy

Int. j. cardiovasc. sci. (Impr.); 37 (suppl.9), 2024
INTRODUÇÃO: A obstrução da via de saída do ventrículo esquerdo (VSVE) ocorre em cerca de 70% dos pacientes com Cardiomiopatia Hipertrófica (CMH), conferindo elevada morbidade e risco de morte súbita. A miectomia cirúrgica e a alcoolização septal são estratégias invasivas já estabelecidas pa...

The decreased left ventricular ejection fraction in patients using trastuzumab deruxtecan for her2-positive breast cancer: a systematic review and meta-analysis

Arq. bras. cardiol; 121 (9 supl.1), 2024
Breast Cancer (BC) is one of the most common cancers diagnosed in population femmale and it has several subtypes, one of them being theexpressing human epidermal growth factor receptor 2 positive (HER2 +), one of the treatments for HER2+ breast cancer consists of chemotherapy plus trastuzumab deruxtecan....

Cardio-protective effects of statins in patients with breast cancer undergoing anthracycline-based chemotherapy: a metaanalysis of randomized controlled trials

Arq. bras. cardiol; 121 (9 supl.1), 2024
BACKGROUND: Contemporary understanding characterizes cardiotoxicity as a reduction in left ventricular ejection fraction (LVEF) by at least 10%, resulting in a final value below 53% in successive assessments. Nevertheless, breast cancer therapy can impact the cardiovascular system through various avenues...

Cardiac tumors: review

Braz J Cardiovasc Surg; 39 (6), 2024
Cardiac tumors are rare and encompass a variety of presentations. Clinica symptoms are usually nonspecific, but they can present as obstructive, embolic, or constitutional symptoms. Treatment options and prognosis vary highly depending on the subtype, tumor size, and location. Surgical resection is usual...

Cardiovascular benefits of statin plus ezetimibe combination therapy versus statin monotherapy in acute coronary syndrome: a meta-analysis of randomized controlled trials

J. Am. Coll. Cardiol; 83 (13 Suppl. A), 2024
BACKGROUND: The efficacy of adding ezetimibe to statin therapy for event reduction in patients with acute coronary syndromes (ACS) remains a topic of ongoing debate. METHODS: We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing ezetimibe plus statin versus s...

Taquicardia ventricular catecolaminérgica com mutação do GENE RYR2 - troca do nucleotídeo C. 7433T>C em família com histórico de síncope e morte súbita
Catecholaminergic ventricular tachycardia with GENE RYR2 mutation - C.7433T>C nucleotide exchange in a family with a history of syncope and sudden death

Arq. bras. cardiol; 119 (5 supl.1), 2022
INTRODUÇÃO: Eventos súbitos na adolescência são sempre dramáticos e causam impacto na família e na sociedade. Histórias recorrentes são subdiagnosticadas e tragédias familiares ficam sem explicação devido à falta de compreensão do generalista sobre as causas de morte súbita sem cardiopatia...

Fístula coronária como causa de angina, um relato de caso
Coronary fistula as a cause of angina, a case report

RELATO DE CASO: EJA, feminino, 57 anos, previamente hipertensa e com história familiar positiva para Doença Arterial Coronariana, referia queixa de angina CCS III há dois anos, progressiva, associada a tontura e síncope. Realizada investigação ambulatorial com cateterismo cardíaco que evidenciou i...

Ablação septal com cateteres e radiofrequência guiada pela ecocardiografia para tratamento de pacientes com cardiomiopatia hipertrófica obstrutiva: Experiência inicial

Arq. bras. cardiol; (), 2022
FUNDAMENTOS: A cardiomiopatia hipertrófica (CMH) pode causar obstrução da via de saída do ventrículo esquerdo (VSVE) e ser responsável pelo surgimento de sintomas limitantes, como cansaço físico. Quando tais sintomas são refratários ao tratamento farmacológico, os tratamentos alternativos inte...