Lima, Kaio Ramon de Aguiar;
Lopes, Maria Luiza Diniz de Sousa;
Souza, Sara Raquel Garcia de;
Fracaro, Luciane;
Purificação, Natan Reyges Castro da;
Lima, Marília Fabiana de Oliveira;
Lins, Lucas Alexandre Araújo;
Lacchini, Silvia;
Araújo, Aurigena Antunes de;
Araújo Júnior, Raimundo Fernandes de;
Perles, Juliana Vanessa Colombo Martins;
Zanoni, Jacqueline Nelisis;
Clebis, Naianne Kelly.
Purpose: To evaluate the effects of the experimental subcutaneous Walker-256 tumor and L-glutamine supplementation, an antioxidant, on the glomerular morphology of rats. Methods: Twenty Wistar rats were distributed into four groups (n = 5): control (C); control treated with 2% L-glutamine (CG); rats with...
Introduction: Experimental animal models represent a key tool used to elucidate the mechanisms of action and toxicity of anticancer drugs. Objective: The purpose was to establish a correlation of neoplastic growth with the combinatorial therapeutic application of sodium alendronate (ALD) and methotrexate...
Abstract The Walker-256 tumor is an important experimental model that allow the development of therapies as the biological behavior of this tumor is similar that occur in humans. In front of the above considerations, the aim of this study was to describe the experimental model of Walker-256 tumor, identi...
ABSTRACT Objective: To evaluate the effect of red propolis and L-lysine on angiogenesis and tumor growth in a new model of hamster cheek pouch inoculated with Walker 256 tumor cells. Methods: The study consisted of two experiments with four groups each (total: 57 hamsters). In the experiment 1, the ani...
Inhibidores de la Angiogénesis/uso terapéutico,
Antioxidantes,
Carcinoma 256 de Walker/irrigación sanguínea,
Mejilla,
Cricetinae,
Lisina/uso terapéutico,
Mesocricetus,
Modelos Animales,
Neoplasias de la Boca/irrigación sanguínea,
Neoplasias de la Boca/inducido químicamente,
Neoplasias de la Boca/tratamiento farmacológico,
Neovascularización Patológica/tratamiento farmacológico,
Própolis/uso terapéutico,
Resultado del Tratamiento,
Aumento de Peso
ABSTRACT PURPOSE: To assess antioxidant effects of açaí seed extract on anorexia-cachexia induced by Walker-256 tumor. METHODS: A population of 20 lab rats were distributed into four groups (n=5): Control Group (CG), which only received tumor inoculation. Experimental Group-100 (EG-100), with anima...
Anorexia/tratamiento farmacológico,
Antioxidantes/farmacología,
Caquexia/tratamiento farmacológico,
Euterpe/química,
Extractos Vegetales/uso terapéutico,
Semillas/química,
Análisis de Varianza,
Anorexia/etiología,
Antioxidantes/análisis,
Caquexia/etiología,
Carcinoma 256 de Walker/complicaciones,
Corteza Cerebral/enzimología,
Peroxidación de Lípido/efectos de los fármacos,
Neoplasias Experimentales/complicaciones,
Estrés Oxidativo/efectos de los fármacos,
Extractos Vegetales/farmacología,
Ratas Wistar,
Síndrome,
Sustancias Reactivas al Ácido Tiobarbitúrico/metabolismo
Videolaparoscopic surgery has enabled great progress in surgical procedures. However, the literature shows great controversy concerning its indication in oncological surgery for possibly increasing the implantation of metastases. This experimental study was carried out to help solve this controversy and ...
Alguns autores tem sugerido que o fornecimento de nutrientes específicos pode melhorar a resposta imunológica e consequentemente o prognóstico do paciente com câncer. Entre estes destaca-se o aminoácido arginina, cuja utilização terapêutica vem sendo investigada em uma variedade de modelos de tum...
Ratos receberam implante de células tumorais (Walker 256) sendo sacrificados 7-21 dias mais tarde. Nesses animais verificou-se queda substancial dos níveis circulantes de T3 e T4 (15-60 por cento) e aumento dos de rT3 (1-3,7 vezes), caracterizando a síndrome do T3 baixo. Estas alteraçöes apresentara...
E estudo polarográfico do oxigênio e metronidazol foi realizado em 52 ratos inoculados com tumor de Walker 256, implantando-se eletrodos de platina no músculo da coxa e no tumor. O objetivo da presente pesquisa foi o estudo das alteraçöes polarográficas, no tumor de Walker 256, com diâmetro aproxi...
