Atypical metastases from prostate cancer detected on 68Ga-PSMA PET/CT: a case series
Int. braz. j. urol; 47 (1), 2021
Results: 30
Unusual manifestation of genital cutaneous leishmaniasis in an immunocompetent patient from São Paulo, Brazil: A case report
Rev. Soc. Bras. Med. Trop; 54 (), 2021
Abstract A 31-year-old male patient developed an ulcer on the glans penis that evolved for three months without healing. We diagnosed it as leishmaniasis using polymerase chain reaction. No immunosuppression or associated diseases were observed. The patient was treated with meglumine antimoniate that cur...
Re: The role of 68Ga-PSMA-PET/CT in radiotherapy planning in prostate cancer
Int. braz. j. urol; 45 (4), 2019
Glicoproteínas de Membrana/uso terapéutico, Estadificación de Neoplasias, Compuestos Organometálicos/uso terapéutico, Tomografía Computarizada por Tomografía de Emisión de Positrones/métodos, Neoplasias de la Próstata/diagnóstico por imagen, Neoplasias de la Próstata/patología, Neoplasias de la Próstata/radioterapia, Radiofármacos/uso terapéutico
Enhancing PSMA-uptake with androgen deprivation therapy - a new way to detect prostate cancer metastases?
Int. braz. j. urol; 45 (3), 2019
ABSTRACT Purpose: 68Ga-PSMA PET/CT imaging is a promising modality for the staging of recurrent prostate cancer (PCa). Current evidence suggests limited diagnostic value of the 68Ga-PSMA PET/CT in PSA-levels ≤0.3ng/mL. Experimental data have demonstrated an increase in PSMA-expression in PCa metas...
Antagonistas de Andrógenos/uso terapéutico, Glicoproteínas de Membrana, Persona de Mediana Edad, Clasificación del Tumor, Metástasis de la Neoplasia/diagnóstico por imagen, Recurrencia Local de Neoplasia/patología, Oligopéptidos/uso terapéutico, Compuestos Organometálicos, Tomografía Computarizada por Tomografía de Emisión de Positrones/métodos, Antígeno Prostático Específico/sangre, Neoplasias de la Próstata/patología, Radiofármacos, Valores de Referencia, Reproducibilidad de los Resultados, Factores de Tiempo
Síntesis y uso de histidinato de cobre en niños con enfermedad de Menkes en México
Gac. méd. Méx; 155 (2), 2019
Resumen La enfermedad de Menkes es una patología neurodegenerativa y letal debida a mutaciones génicas de la enzima ATP-7A trasportadora de cobre; se manifiesta por síntomas neurológicos y alteraciones del tejido conectivo de severidad variable. El uso subcutáneo oportuno de histidinato de cobre (Cu...
Cobre/sangre, Composición de Medicamentos/métodos, Histidina/administración & dosificación, Histidina/efectos adversos, Histidina/análogos & derivados, Síndrome del Pelo Ensortijado/tratamiento farmacológico, México, Compuestos Organometálicos/administración & dosificación, Compuestos Organometálicos/efectos adversos, Soluciones Farmacéuticas, Calidad de Vida
Diversity of metallo-b-lactamase-encoding genes found in distinct species of Acinetobacter isolated from the Brazilian Amazon Region
Mem. Inst. Oswaldo Cruz; 114 (), 2019
BACKGROUND The multidrug resistance (MDR) phenotype is frequently observed in Acinetobacter baumannii, the most clinically relevant pathogenic species of its genus; recently, other species belonging to the A. calcoaceticus-A. baumannii complex have emerged as important MDR nosocomial pathogens. OBJECTI...
Avaliação in silico da interação entre o receptor GABAA e metalocompostos derivados de benzodiazepínicos
O receptor do ácido γ-aminobutírico do tipo A (GABAA) é o receptor de ação rápida mais amplamente distribuído no sistema nervoso central (SNC) dos mamíferos. Os receptores GABAA são canais iônicos pentaméricos transmembranares e apresentam alta heterogeneidadede entre suas subunidades. Quando...
New metallophamaceutic reduced renal injury induced by non-steroidal anti-inflammatory
Acta cir. bras; 34 (12), 2019
Abstract Purpose To evaluate the effect of Rut-bpy (Cis-[Ru(bpy)2(SO3)(NO)]PF 6), a novel nitric oxide donor, able to modulate the histological changes caused by the NASID (meloxicam). Methods Wistar rats were assigned into three groups (n=6 rats/group): Sham group (saline solution), NSAID group (mel...
Antiinflamatorios no Esteroideos/efectos adversos, Fractales, Enfermedades Renales/inducido químicamente, Enfermedades Renales/patología, Enfermedades Renales/prevención & control, Meloxicam/efectos adversos, Donantes de Óxido Nítrico/farmacología, Compuestos Organometálicos/farmacología, Distribución Aleatoria, Ratas Wistar, Reproducibilidad de los Resultados, Rutenio/farmacología
Combination therapy with liposomal amphotericin b (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate in a refractory visceral leishmaniasis case
Rev. Soc. Bras. Med. Trop; 51 (3), 2018
Abstract Visceral leishmaniasis is a systemic disease that is potentially severe and endemic in Brazil. It clinically manifests as fever, weight loss, swelling, hepatosplenomegaly, paleness, and edema. In this study, we discuss a case of a 1-year-old child diagnosed with refractory visceral leishmaniasis...
Anfotericina B/administración & dosificación, Antiprotozoarios/administración & dosificación, Quimioterapia Combinada, Leishmaniasis Visceral/tratamiento farmacológico, Meglumina/administración & dosificación, Antimoniato de Meglumina, Compuestos Organometálicos/administración & dosificación, Pentamidina/administración & dosificación
The maturation state of the auditory nerve and brainstem in rats exposed to lead acetate and supplemented with ferrous sulfate
Braz. j. otorhinolaryngol. (Impr.); 84 (2), 2018
Abstract Introduction The literature has reported the association between lead and auditory effects, based on clinical and experimental studies. However, there is no consensus regarding the effects of lead in the auditory system, or its correlation with the concentration of the metal in the blood. Obje...