Results: 23

Amiloidose renal familiar em cães da raça Shar-Pei

Vet. zootec; 31 (), 2024
A amiloidose renal familiar é uma doença incomum em cães, que afeta os rins e está associada ao acúmulo anormal de proteínas amiloides, com capacidade de promover danos orgânicos progressivos com comprometimento de funcionalidade. Caracterizada pela presença de conteúdo proteináceo glomerular, ...

L-glutamine supplementation reduced morphological damage in the renal glomerulus of rats with Walker-256 tumor

Acta cir. bras; 38 (), 2023
Purpose: To evaluate the effects of the experimental subcutaneous Walker-256 tumor and L-glutamine supplementation, an antioxidant, on the glomerular morphology of rats. Methods: Twenty Wistar rats were distributed into four groups (n = 5): control (C); control treated with 2% L-glutamine (CG); rats with...

Morphometry: assessing direct and indirect methods of measuring the diameters of tubular structures

Int. j. morphol; 40 (2), 2022
SUMMARY: Knowledge of the diameter of a structure or particle is required for stereological calculations. However, there is no consensus on the methodology for its measurement. This study aims to assess the differences between direct and indirect methods of measuring diameter. It is hypothesised that kid...

Quercetin as a nephroprotector after warm ischemia: histomorphometric evaluation in a rodent model

Int. braz. j. urol; 47 (4), 2021
ABSTRACT Purpose: To quantitatively evaluate the possible long-term protective effects of quercetin during renal warm ischemia. Materials and Methods: Male rats were allocated into 4 groups: sham (S), sham quercetin (SQ), ischemia (I), and ischemia quercetin (IQ). Groups SQ and IQ received quercetin (5...

A rare case of PLA2R- and THSD7A-positive idiopathic membranous nephropathy

J. bras. nefrol; 42 (2), 2020
ABSTRACT Idiopathic membranous nephropathy (IMN) is a frequent cause of nephrotic syndrome in adults. In terms of etiology, the condition may be categorized as primary/idiopathic or secondary. Literature on the pathophysiology of IMN has indicated the presence of autoantibodies (PLA2R and THSD7A) directe...

Anca negative pauci-immune crescentic glomerulonephritis and mixed connective tissue disease: a case study

J. bras. nefrol; 42 (2), 2020
Abstract One of the most common causes of rapidly progressive glomerulonephritis (RPGN) is pauci-immune crescentic glomerulonephritis (CrGN). In the majority of cases, this condition has a positive serologic marker, the anti-neutrophil cytoplasmic antibodies (ANCAs), but in approximately 10% there are no...

Renal histological alterations induced by acute exposure of titanium dioxide nanoparticles

Int. j. morphol; 37 (3), 2019
SUMMARY: Titanium dioxide nanoparticles (TiO2 NPs) are widely used in many commercial products, nanomedicine, agriculture, personal care products, different industries and pharmaceutical preparations with potential risk in human health and the environment. The current work was conducted to investigate th...

Different sample preparation methods for glomerular morphological evaluation: to coat or not to coat?

Int. j. morphol; 37 (2), 2019
The renal glomerulus is coated by fenestrated endothelial cells and externally covered by specialized epithelial cells, known as podocytes. Scanning electron microscopy becomes an important and effective tool for its studies. Normally, samples destined for scanning microscopy are covered with a thin meta...

Trastornos glomerulares en la práctica médica
Glomerulopathies in the medical practice

Rev. medica electron; 41 (3), 2019
RESUMEN Las glomerulopatías agrupan varias nefropatías con lesiones fundamentalmente del corpúsculo renal y que se expresan principalmente por proteinuria, hematuria, edemas e hipertensión arterial. La presentación clínica varía en dependencia del tipo de enfermedad de que se trate. Constituye la ...

Recurrencia de Síndrome de Goodpasture con negativización de anticuerpos anti-membrana basal glomerular: caso clínico

Rev. méd. Chile; 147 (3), 2019
Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative...