The case is presented on a 52-year-old male patient, who was seen in the Rheumatology department. He had painless lymph nodes in the cervical, axillary, supraclavicular, and neck region. He also had a fever, and parotid and submaxillary gland enlargement. Complementary studies were performed, showing nor...
The Rosai-Dorfman disease (RDD) is a bening entity, of unknown etiology, rare, characterized by the overproduction of histiocytes and their subsequent accumulation in the lymph nodes, which may also compromise other organs and systems. It predominantly affects young people. The histological study, which ...
Resumen La histiocitosis sinusal con linfadenopatÃas masivas, conocida como enfermedad de Rosai-Dorfman (ERD), es una patologÃa poco frecuente cuya presentación clásica consiste en el desarrollo de grandes adenopatÃas cervicales bilaterales indoloras. La manifestación extranodal puede involucrar co...
La enfermedad de Rosai-Dorfman (ERD) o histiocitosis sinusal con linfadenopatÃa
masiva (HSLM) es una entidad histiocÃtica benigna rara, que usualmente afecta
los ganglios linfáticos. Se han descrito algunos casos en el sistema nervioso
central, y son excepcionales los que aparecen sin afección nodula...
RESUMEN La enfermedad de Rosai-Dorfman (ERD) o histiocitosis sinusal con linfadenopatÃa masiva es una enfermedad infrecuente, de etiologÃa desconocida caracterizada por linfadenopatÃas cervicales masivas bilaterales. El compromiso extraganglionar puede ocurrir en diferentes sitios, incluida la vÃa aÃ...
Abstract: A 75-year-old male presented with generalized erythematous, scaly plaques and painless lymphadenopathy. Rosai-Dorfman disease was suspected based on clinical manifestations and confirmed by histopathologic and immune reactivity studies performed on the biopsy obtained from the left supraclavicu...
Rosai-Dorfman disease is a benign lymphoproliferative disease with rare occurrence in
the overall population. The characteristic findings of the disease are emperipolesis on
microscopy and S-100 protein positivity on immunohistochemistry. The present report
describes the case of a 57-year-old man who pre...
Abstract: Rosai-Dorfman disease is a benign histiocytic proliferative disorder of unknown etiology. The disease mainly affects lymph node tissue, although it is rarely confined to the skin. Here, we describe a 53-year-old woman with purely cutaneous Rosai-Dorfman disease. The patient presented with a lar...
La enfermedad de Rosai-Dorfman; también conocida como linfadenopatÃa masiva con histiocitosis sinusal; es un raro desorden de etiologÃa desconocida; generalmente asociado a un agrandamiento de los ganglios linfáticos superficiales y/o profundos. La mayorÃa de los pacientes no requiere tratamiento. P...
