Los procedimientos endodónticos regenerativos (REPs) representan una evolución significativa en el campo de la endodoncia, buscando no sólo tratar la infección o lesión presente en el diente, sino tam-bién promover la regeneración de los tejidos denta-rios afectados. El presente caso clín...
Abstract The purpose of the present study was to develop stable lyophilized formulation of peginterferon alfa-2b which is acquiescent to the short lyophilization process. The present study evaluates the effect of buffering components and cryoprotectant(s) on depegylation of the peginterferon alfa-2b in c...
Abstract Candidiasis is one of the most common fungal infections of oral cavity in humans, causing great oral discomfort, pain and aversion to food. To develop more effective antifungal systems for the treatment of oral candidiasis, an oral mucoadhesive wafer containing sertaconazole solid dispersion (ST...
Introdução: o uso de substitutos cutâneos para o tratamento de diversas feridas graves é uma forma eficiente de prevenir infecções e favorecer o processo de reepitelização. No entanto, tecidos biológicos estão suscetíveis a degradação e contaminação. Por isso, devem ser submetidos a rigoro...
El arándano (Vaccinium corymbosum L.) posee un alto contenido de compuestos fenólicos los cuales han sido estudiados principalmente por su actividad antioxidante, antiobesogénica, antiinflamatoria, entre otras. Objetivo. Evaluar el efecto de la digestión gastrointestinal in vitro sobre la bioaccesibi...
Background: One of the most used and effective preservation strategies in foods is drying. However, there are problems with the rheological properties, color, and viability of lactic acid bacteria in the yogurt once reconstituted when applying such conservation strategies. Objectives: Det...
Platelet-rich plasma (PRP) has been considered a promising therapeutic alternative, since platelets are rich in growth factors that are used in the Regenerative Medicine field. However, fresh PRP cannot be stored for long periods. This study aimed to develop a protocol for obtaining lyophilized canine PR...
Background: Freeze-drying is known as one of the best methods to preserve bacterial strains. Protectant is the key factor affecting the survival rate of freeze-dried strains. In addition, salinity, bacterial suspension concentration, drying time, and other factors can also affect the survival rate of str...
Pseudoalteromonas/fisiología,
Liofilización/métodos,
Preservación Biológica/métodos,
Viabilidad Microbiana,
Fenómenos Fisiológicos Bacterianos,
Supervivencia Celular,
Lactosa/química,
Disacáridos/química,
Manitol/química,
Salinidad,
Trehalosa/química
Many chronic diseases require repetitive injections as maintenance treatment. It is therefore important to investigate a possible alternative. A simulated subcutaneous implant prototype was fabricated as a polymer matrix covered by cylinder-shape tubing having a porous membrane. Sucrose, bovine serum alb...
Implantes de Medicamentos/metabolismo,
Preparaciones de Acción Retardada,
Técnicas In Vitro,
Cromatografía Líquida de Alta Presión,
Liofilización,
28574,
Evaluación Preclínica de Medicamentos,
Preparaciones Farmacéuticas/administración & dosificación,
Tejido Subcutáneo,
Proyectos Piloto,
Liberación de Fármacos
Objetivos. Determinar la estabilidad de cremas fotoprotectoras a base de Myrcianthes rhopaloides «lanche colorado» de los páramos de Piura. Materiales y métodos. Se evaluaron tres extractos hidroetanólicos y dos acuosos que fueron purificados con Amberlite® XAD7HP. Se formularon cremas fotoprotecto...
