Abstract This study aimed to develop and evaluate the stability of sulfadiazine sugar-free extemporaneous oral suspensions, focusing on treating congenital toxoplasmosis. The excipients were carefully chosen to obtain safe products for the pediatric population. Sulfadiazine suspensions (100 mg/ mL) were ...
Abstract This work aims to ascertain the comprehensiveness of dissolution tests for oral suspensions registered in Brazil and the USA. After consulting literature since 1994, a paucity of information about dissolution methods for suspensions was detected. It makes it difficult to establish the most appro...
The aim of this work was to perform solubility studies for fexofenadine hydrochloride and establish dissolution conditions for this drug in oral suspension dosage form. The solubility study was executed through the shake-flask method, below 37 ºC±1 ºC, at 100 rpm stirring for 12 h in three buffer solu...
Este trabalho teve por finalidade desenvolver um método para a caracterização do perfil de dissolução de suspensões de mebendazol (MBZ), discriminatório para as formas polimórficas do fármaco. Pertencendo a classe II do Sistema de Classificação Biofarmacêutica (SCB), além da baixa solubilida...
Abstract Objective: Study the use of magistral oral solutions and suspensions in infants and children at a university hospital. Methods: This is a descriptive study based on the analysis of the assessed hospital's magistral drug request forms regarding the patients in the neonatal ICU, Obstetrics, Pedi...
Objetivo Analizar la suspensión de cirugías en el Hospital de Trauma Dr. Federico Abete en el año 2014. Método Se analizaron datos de 441 cirugías suspendidas en la Unidad de Quirófano del Hospital de Trauma Dr. Federico Abete entre el 1 de enero y el 31 de diciembre de 2014. Se definió como susp...
Background Three oligosaccharides (EOS, WOS and SOS) were respectively prepared from the corresponding polysaccharides, namely exopolysaccharide (EPS), water-extracted mycelial polysaccharide (WPS) and sodium hydroxide-extracted mycelial polysaccharides (SPS) from the endophytic fungus Fusarium oxysporum...
Oligosacáridos/metabolismo,
Fusarium,
Endófitos,
Fenilanina Amoníaco-Liasa/metabolismo,
Peroxidasa/metabolismo,
Catecol Oxidasa/metabolismo,
Polisacáridos,
Dioscorea,
Células Vegetales,
Técnicas de Cultivo de Célula,
Suspensiones,
Resistencia a la Enfermedad
En este trabajo de investigación se exponen los resultados obtenidos al realizar la corrección organolética de un sistema oral heterodisperso de sabor amargo y otro de sabor salado, para lograr armonizar el sabor desagradable que se desea enmascarar mediante la utilización de esencias, elegidas por u...
Una de las características para el cumplimiento adecuado del tratamiento con un antibiótico líquido en la edad pediátrica es que el gusto y la sensación posterior a la ingestión sean acetables al paladar del niño. Se comparan siete suspensiones de antimicrobianos (cinco ampicilinas y dos trimetopr...
