Results: 12

Primer reporte de caso autóctono de tinea nigra en Chile

Medwave; 19 (6), 2019
Resumen La tinea nigra es una infrecuente micosis superficial causada por el hongo dematiáceo Hortaea werneckii. Se presenta habitualmente en zonas costeras tropicales, siendo muy escasos los reportes en países sudamericanos con climas más templados. Habitualmente corresponde a infecciones importadas ...

Beneficial effects of Oltipraz, nuclear factor - erythroid - 2 - related factor 2 (Nrf2), on renal damage in unilateral ureteral obstruction rat model

Int. braz. j. urol; 44 (6), 2018
ABSTRACT Introduction: We investigated whether Oltipraz (OPZ) attenuated renal fibrosis in a unilateral ureteral obstruction (UUO) rat model. Materials and Methods: We randomly divided 32 rats into four groups, each consisting of eight animals as follows: Rats in group 1 underwent a sham operation and ...

Strontium ranelate as a possible disease-modifying osteoarthritis drug: a systematic review

Braz. j. med. biol. res; 51 (8), 2018
Considering that osteoarthritis (OA) is the most prevalent joint disease worldwide, multiple pharmacological treatments have been proposed to alter the articular structure with potential benefit in the progression of the disease. The so-called disease-modifying OA drugs have been frequently investigated ...

Strontium ranelate inhibits wear particle-induced aseptic loosening in mice

Braz. j. med. biol. res; 51 (9), 2018
The imbalance between bone formation and osteolysis plays a key role in the pathogenesis of aseptic loosening. Strontium ranelate (SR) can promote bone formation and inhibit osteolysis. The aim of this study was to explore the role and mechanism of SR in aseptic loosening induced by wear particles. Twent...

Effects of strontium ranelate on alveolar ridge morphology augmentation

Int. j. morphol; 35 (4), 2017
SUMMARY: The objective of this study was to compare the Primary and Secondary stability of immediate implant placement with Alveolar Ridge Augmentation (ARA) and Strontium Ranelate (SR) as aids to enhance the stability using Resonance Frequency Analysis (RFA). Fifty eight subjects ideal for immediate imp...

Efecto del ranelato de estroncio sobre la densidad mineral ósea en hombres con osteoporosis
Effect of strontium ranelate on bone mineral density in men with osteoporosis

Actual. osteol; 13 (3), 2017
La osteoporosis afecta al 6-7% de la población masculina. Es alta la proporción de pacientes con fracturas sin diagnóstico previo de esta enfermedad. La mortalidad luego de una fractura es mayor en hombres que en población femenina; a pesar de esto, la mayoría de los pacientes no reciben tratamiento...

Erdosteine ameliorates the harmful effects of ischemia-reperfusion injury on the liver of rats

Acta cir. bras; 32 (10), 2017
Abstract Purpose: To investigate the potential protective effects of erdosteine against the harmful effects of ischemia-reperfusion injury on the liver in an experimental rat model. Methods: Forty rats were divided into 4 groups. In the sham group, only the hepatic pedicle was mobilized. No other mani...

Drug-induced Liver Injury Caused by Ipragliflozin Administration with Causality Established by a Positive Lymphocyte Transformation Test (LTT) and the Roussel Uclaf Causality Assessment Method (RUCAM): A Case Report

Ann. hepatol; 16 (2), 2017
ABSTRACT A 75-year old male patient had been regularly visiting our hospital for the management of his type 2 diabetes mellitus since he was diagnosed at age 64 years. When he developed hypoglycemic episodes with sulfonylurea, ipragliflozin (50 mg/day) was started to replace the sulfonylurea therapy. How...

Efectos in vivo del ranelato de estroncio sobre células progenitoras de médula ósea de ratas diabéticas
In vivo effects of strontium ranelate on bone marrow progenitor cells of diabetic rats

Actual. osteol; 12 (2), 2016
La diabetes mellitus (DM) crónica se asocia con reducción en el contenido mineral óseo (osteopenia y osteoporosis). El objetivo de este trabajo fue evaluar la acción del ranelato de estroncio (RaSr) administrado por vía oral a animales control y diabéticos, sobre el potencial osteogénico de célul...

Sequential administration of alendronate and strontium ranelate: histomorphometry and bone biomechanics in ovariectomized animals

Acta odontol. latinoam; 29 (2), 2016
Bisphosphonates are the first choice therapy for the pharmaco logical treatment of osteoporosis. Following reports of cases of bisphosphonaterelated osteonecrosis of the jaw and atypical femur fracture, the safety of longterm use of bisphosphonates has been evaluated, resulting in the proposal of stronti...