Obesity: A Risk Marker or an Independent Risk Factor for Coronary Artery Disease?
Int. j. cardiovasc. sci. (Impr.); 33 (1), 2020
Results: 372
Comment on usefulness of atherogenic indices and Ca-LDL level to predict subclinical atherosclerosis in patients with psoriatic arthritis?
Adv Rheumatol; 60 (), 2020
¿son la velocidad de la onda del pulso y la rigidez arterial marcadores para evaluar aterosclerosis pre-clínica en pacientes con hipertensión resistente?
Rev. cientif. cienc. med; 23 (1), 2020
Introducción: La velocidad de la onda de pulso y la rigidez arterial se considera estándar de oro para evaluar daño a órganos diana que haya surgido subclinicamente. La disfunción endotelial es directamente proporcional al desarrollo de la aterosclerosis preclínica. Estos marcadores sustitutos menc...
COVID-19 grave: entenda o papel da imunidade, do endotélio e da coagulação na prática clínica
J. vasc. bras; 19 (), 2020
Resumo O SARS-CoV-2 é o responsável pela pandemia da COVID-19. O sistema imunológico é fator determinante no combate à infecção viral e, quando atua equilibrada e eficientemente, a doença é autolimitada e benigna. Uma parcela significativa da população, porém, apresenta resposta imune exacerb...
Up-regulated miR-106b inhibits ox-LDL-induced endothelial cell apoptosis in atherosclerosis
Braz. j. med. biol. res; 53 (3), 2020
This research aimed to explore the molecular mechanism of microRNA (miR)-106b in cell apoptosis of atherosclerosis (AS). Human aortic endothelial cells (HAECs) were divided into control group, oxidized-low-density lipoproteins (ox-LDL) group, miR-106b NC+ox-LDL group, miR-106b mimics+ox-LDL group, miR-10...
The APOB rs693 polymorphism impacts the lipid profile of Brazilian older adults
Braz. j. med. biol. res; 53 (3), 2020
The apolipoprotein B (APOB) gene contains several polymorphic sites described as risk modifiers for cardiovascular events. The objective of this study was to verify the association of the classic APOB Xba I polymorphism (rs693) with atherosclerotic risk factors in a segment of the Brazilian elderly popul...
Apolipoproteínas B/genética, Aterosclerosis/sangre, Aterosclerosis/genética, Brasil, Enfermedades Cardiovasculares/sangre, Ingestión de Energía, Conducta Alimentaria, Frecuencia de los Genes, Predisposición Genética a la Enfermedad/genética, Genotipo, Lípidos/sangre, Polimorfismo Genético/genética, Factores de Riesgo
Animal models of human atherosclerosis: current progress
Braz. j. med. biol. res; 53 (6), 2020
Atherosclerosis retains the leading position among the causes of global morbidity and mortality worldwide, especially in the industrialized countries. Despite the continuing efforts to investigate disease pathogenesis and find the potential points of effective therapeutic intervention, our understanding ...
LncRNA HCG11 regulates proliferation and apoptosis of vascular smooth muscle cell through targeting miR-144-3p/FOXF1 axis in atherosclerosis
Biol. Res; 53 (), 2020
BACKGROUND: Atherosclerosis (AS) is the main pathological basis of coronary heart disease, cerebral infarction and peripheral vascular disease, which seriously endanger people's life and health. In recent years, long non-coding RNA (lncRNA) has been found to be involved in gene expression regulation, but...
Effect of Cilostazol-Loaded PCL/PEG Nanocapsules on Abdominal Aortic Tunics and Lipid Profile of Wistar Rats
Braz. arch. biol. technol; 63 (), 2020
Abstract Cilostazol (CLZ) is a phosphodiesterase III inhibitor with antiplatelet and vasodilator properties. It has been recently verified that CLZ plays a significant role in the arteries by inhibiting the proliferation and growth of muscle cells, increasing the release of nitric oxide by the endotheliu...
Cilostazol/administración & dosificación, Nanocápsulas/administración & dosificación, Vasodilatadores/administración & dosificación, Aterosclerosis/prevención & control, Aorta Abdominal, Inhibidores de Fosfodiesterasa 3/administración & dosificación, Ratas Wistar, Óxido Nítrico, Glicoles de Propileno, Inhibidores de Agregación Plaquetaria/administración & dosificación, Modelos Animales de Enfermedad
Nutrición cardiometabólica en el mundo real de la práctica clínica
Cardiometabolic nutrition in the real world of clinical practice
Med. interna (Caracas); 36 (2), 2020
La importancia de la nutrición en modificar el riesgo de enfermedad cardiovascular aterosclerótica (ECVA) se ha enfatizado repetidas veces. Históricamente, el papel de los componentes dietarios ha sido el foco predominante; sin embargo, los alimentos, típicamente, se consumen en combinación más que...