Results: 120

Efecto del 27- hidroxicolesterol en la acción antiplaquetaria de estradiol en mujeres postmenopáusicas

Rev. méd. Chile; 144 (11), 2016
Background: The decline of estrogen levels increases cardiovascular risk in women. Platelets express estrogen receptors and 17β-estradiol- (E2) can produce a protective effect on thrombus formation. The hydroxylation of cholesterol generates several sterols and 27-hydroxycholesterol (27HC) predomina...

Effect of estrogen administration on middle cerebral arterial viscoelastic properties in aged female rats

Acta cir. bras; 31 (10), 2016
ABSTRACT PURPOSE: To develop a model for studying cerebrovascular disease prevention in elderly women. METHODS: Sixty 18-month-old Sprague Dawley (SD) rats were randomly divided into an estrogen administration group (EA, n=30) and a non-administration group (NA, n=30); thirty 4-month-old SD rats were a...

Estrogen deficiency in ovariectomized rats: can resistance training re-establish angiogenesis in visceral adipose tissue?

Clinics; 71 (9), 2016
OBJECTIVE: The purpose of this study was to investigate the effects of resistance training on angiogenesis markers of visceral adipose tissue in ovariectomized rats. METHOD: Adult Sprague-Dawley female rats were divided into four groups (n=6 per group): sham-sedentary, ovariectomized sedentary, sham-res...

Sexualidad y climaterio: una mirada integral
Sexuality and climacteric: a comprehensive approach

Cuando hablamos de sexualidad humana debemos saber que estamos hablando de una compleja y cambiante interacción de factores biológicos y socioemocionales altamente influenciables por la familia, la religión y los patrones culturales. Esto se ve en los hombres y en las mujeres, especialmente en las muj...

Estrogen signaling in the proliferative endometrium: implications in endometriosis

SUMMARY Even though the physiological role of estrogen in the female reproductive cycle and endometrial proliferative phase is well established, the signaling pathways by which estrogen exerts its action in the endometrial tissue are still little known. In this regard, advancements in cell culture techni...

Influência da terapêutica hormonal estrogênica e do treinamento de força sobre o tecido muscular esquelético de ratas senis

A diminuição das concentrações plasmáticas de estrógeno está intimamente relacionada com o aumento do estresse oxidativo e a diminuição da massa muscular em idosos. A terapêutica hormonal estrogênica (THE) e o treinamento de força (TF) apresentam resultados efetivos sobre a manutenção do te...

Using agents that suppress bone remodeling to treat or prevent joint disease: quo vadis?

Actual. osteol; 12 (3), 2016
Treatment of osteoarthritis (OA) with antiremodeling agents has had a mixed record of results. It is likely that remodeling suppression is only effective when used in the early phases of OA, before significant progression. Animal and human studies largely bear this out. Treatment of young mice with a RAN...

Regulamentação do estrogênio sintético 17-etinilestradiol em matrizes aquáticas na Europa, Estados Unidos e Brasil

O estrogênio sintético 17α-etinilestradiol, principal componente utilizado em formulações de contraceptivos orais, tem sido apontado como um dos principais compostos responsáveis por provocar efeitos adversos no sistema endócrino de várias espécies. O objetivo deste estudo foi analisar o est...

Etapas del climaterio y función endotelial en mujeres de edad mediana
Climacteric stages and endothelial function in middle-aged women

Rev. cuba. endocrinol; 26 (2), 2015
Introducción: La disminución de los estrógenos durante el climaterio repercute negativamente en el endotelio vascular, y origina disfunción endotelial, cuyo significado clínico está aún por definir. Objetivo: determinar la frecuencia de disfunción endotelial en las etapas del climaterio. Métodos...