Perforating necrobiosis lipoidica: good response to adalimumab
An. bras. dermatol; 94 (6), 2019
Results: 312
Lobular capillary hemangioma in a patient with ankylosing spondylitis using adalimumab: an exuberant presentation
An. bras. dermatol; 94 (6), 2019
Abstract Lobular capillary hemangioma or pyogenic granuloma is a benign vascular tumor of the skin or mucous membranes. Most patients present a single lesion. It manifests clinically as an erythematous, friable, and fast-growing tumor. This report details a case with exuberant presentation in a patient w...
Adalimumab/uso terapéutico, Antirreumáticos/uso terapéutico, Granuloma Piogénico/etiología, Granuloma Piogénico/patología, Enfermedades de la Piel/etiología, Enfermedades de la Piel/patología, Espondilitis Anquilosante/complicaciones, Espondilitis Anquilosante/tratamiento farmacológico, Factor de Necrosis Tumoral alfa/antagonistas & inhibidores
Association of tnf-α-308g>a polymorphismand celiac disease
Arq. gastroenterol; 56 (4), 2019
Alteração da motilidade do esôfago durante percepção do trânsito do bolo em voluntários saudáveis
Arq. gastroenterol; 56 (4), 2019
ABSTRACT BACKGROUND: The perception of bolus transit through the thoracic esophagus may be caused by altered esophageal anatomy and function. OBJECTIVE: To evaluate the hypothesis that, in healthy volunteers, swallows followed by perception of esophageal bolus transit are associated with changes in e...
Effects of anti-TNF-α in experimental diversion colitis
Acta cir. bras; 34 (10), 2019
Abstract Purpose: To evaluate the effects of infliximab on the inflammation of the colonic mucosa devoid from fecal stream. Methods: Twenty-four rats were submitted to a Hartmann's procedure. They remained for 12 weeks with the fecal derivation to development of diversion colitis on excluded colorectal...
Colitis/tratamiento farmacológico, Colitis/patología, Colon/efectos de los fármacos, Colon/patología, Heces, Fármacos Gastrointestinales/farmacología, Tránsito Gastrointestinal/efectos de los fármacos, Procesamiento de Imagen Asistido por Computador, Inmunohistoquímica, Infliximab/farmacología, Mucosa Intestinal/efectos de los fármacos, Mucosa Intestinal/patología, Infiltración Neutrófila/efectos de los fármacos, Peroxidasa/análisis, Ratas Wistar, Reproducibilidad de los Resultados, Factores de Tiempo, Factor de Necrosis Tumoral alfa/antagonistas & inhibidores
Lipopolysaccharide-stimulated intracellular cytokines and depressive symptoms in community-dwelling older adults
Arch. Clin. Psychiatry (Impr.); 46 (5), 2019
Abstract Background Inflammation is involved in the pathophysiology of depression, and circulating inflammatory cytokines have been associated with depressive symptoms. However, measuring circulating cytokines have inherent methodological limitations. In vitro lipopolysaccharide (LPS)-stimulated intrac...
Citocinas/sangre, Lipopolisacáridos, Depresión/fisiopatología, Estudios Transversales, Inflamación/fisiopatología, Biomarcadores/sangre, Monocitos/metabolismo, Escalas de Valoración Psiquiátrica, Interleucina-6/sangre, Proteína C-Reactiva, Factor de Necrosis Tumoral alfa/sangre, Técnicas In Vitro, Depresión/sangre, Inflamación/sangre
Frequência de utilização da terapia biológica para doenças inflamatórias intestinais na América Latina: situação atual e desafios futuros
Arq. gastroenterol; 56 (3), 2019
ABSTRACT BACKGROUND: The introduction of anti-TNF agents represented a landmark in the management of both Crohn's disease (CD) and ulcerative colitis (UC), with improved efficacy and safety when compared with conventional treatment. However, significant challenges still exist in Latin America to facili...
Plasmatic adipocyte biomarkers and foot pain associated with flatfoot in schoolchildren with obesity
Rev. Assoc. Med. Bras. (1992, Impr.); 65 (8), 2019
SUMMARY OBJECTIVE The aim of this study was to determine the potential association of foot pain and plasmatic adipocytes as physiological biomarkers of childhood obesity with the incidence of flatfoot in a cohort of Egyptian school children aged 6 -12 years. METHODS A total of 550 Egyptian schoolchil...
Adipocitos/química, Adiponectina/sangre, Biomarcadores/sangre, Índice de Masa Corporal, Estudios de Cohortes, Estudios Transversales, Ensayo de Inmunoadsorción Enzimática, Pie Plano/sangre, Pie Plano/complicaciones, Interleucina-6/sangre, Leptina/sangre, Obesidad/sangre, Obesidad/complicaciones, Dolor/sangre, Dolor/etiología, Dimensión del Dolor, Resistina/sangre, Índice de Severidad de la Enfermedad, Factor de Necrosis Tumoral alfa/sangre
El caseinato de sodio y la caseína α inhiben la proliferación de la línea celular mieloide de ratón 32D clone 3 (32Dcl3) mediante el TNF-α
Biomédica (Bogotá); 39 (2), 2019
Resumen Introducción. Se ha demostrado que el caseinato de sodio y sus componentes (caseínas α, β y κ) inhiben la proliferación de la línea celular hematopoyética de ratón 32D clone 3 (32Dcl3) e inducen su diferenciación hacia macrófagos. Se sabe que la caseína α induce la p...
Caseínas/farmacología, Células Mieloides/efectos de los fármacos, Mielopoyesis/efectos de los fármacos, Factor de Necrosis Tumoral alfa/fisiología, Apoptosis/efectos de los fármacos, División Celular/efectos de los fármacos, Línea Celular, Supervivencia Celular/efectos de los fármacos, Células Clonales, Macrófagos/citología, Células Mieloides/citología, Factor de Necrosis Tumoral alfa/antagonistas & inhibidores, Factor de Necrosis Tumoral alfa/biosíntesis
Ginger extract ameliorates renal damage in high fat diet-induced obesity in rats: biochemical and ultrastructural study
Int. j. morphol; 37 (2), 2019
Obesity is a modifiable risk factor for the development and progression of kidney disease. Obesity may harm kidneys in individuals without hypertension, diabetes, or pre-existing renal disease. Ginger, Zingiber officinale, has many beneficial pharmaceutical benefits. This study aimed to evaluate the Zing...
Obesidad/complicaciones, Dieta Alta en Grasa/efectos adversos, Zingiber officinale/química, Extractos Vegetales/farmacología, Ratas Sprague-Dawley, Enfermedades Renales/tratamiento farmacológico, Enfermedades Renales/patología, Microscopía Electrónica de Transmisión, Riñón/patología, Peso Corporal, Leptina/análisis, Factor de Necrosis Tumoral alfa/análisis, Creatinina/análisis