Results: 424

Detección de ARNm de oncoproteínas E6/E7 del Virus del Papiloma Humano en cáncer de cuello uterino

La infección de transmisión sexual por el Virus del Papiloma Humano (VPH) es una de las más comunes en el mundo. Los VPH se clasifican en bajo riesgo y alto riesgo. Los VPH de bajo riesgo son los causantes de lesiones benignas como verrugas genitales y condilomas acuminados, mientras que los VPH de al...

Asma e DPOC: duas faces de um mesmo dado?

Os imbricados processos patogênicos da asma e da doença pulmonar obstrutiva crônica (DPOC) têm mecanismos comuns que envolvem redes genéticas, subclasses de linfócitos, diversas citocinas e quimiocinas, gerando comportamento alterado de todas as células estruturais e funcionais do trato respirató...

Corticoterapia

Glicocorticosteroides são fármacos efetivos no tratamento de doenças inflamatórias e imunes. Agem em praticamente todas as células do corpo, antagonizando os efeitos patogênicos de inúmeras doenças. A maior parte de seus efeitos parece ser produto de sua ligação a receptores específicos armaze...

Estructura molecular de los ácidos nucleicos. Una estructura para el Ácido Desoxirribonucleico
The molecular structure of nucleic acids. An structure for Desoxirribonucleic acid

Deseamos sugerir una estructura para la sal del Ácido Desoxirribonucleico (A.D.N.). Esta estructura tiene aspectos novedosos que son de un interés biológico considerable. Una estructura para el ácido nucleico ya ha sido propuesta por Pauling y Corey:1 Amablemente han puesto el manuscrito a nuestra d...

Synthesis, antibacterial activity and DNA interactions of lanthanide(IU) complexes of N(4)-substituted thiosemicarbazones

Univ. sci; 23 (2), 2018
Abstract This paper reports the synthesis and detailed characterization of six novel lanthanide complexes of La(III), Eu(III) and Nd(III) with N(4)-substituted thiosemicarbazones derived from the 2-carboxybenzaldehyde. The IR, 1H-NMR and 13C-NMR spectroscopic studies confirmed the coordination of the thi...

Gliomas malignos: biología molecular y detalles oncogenéticos
Wicked gliomas: molecular biology and oncogenetics detail

Rev. medica electron; 40 (4), 2018
RESUMEN La biología de los gliomas malignos se asocia con el balance de la expresión de las proteínas que controlan de manera positiva o negativa el ciclo celular, la proliferación, la motilidad, la neoformación vascular y el reconocimiento del sistema inmune. La frecuencia de las alteraciones gené...

Western diet induces endogen oxidative deoxyribonucleic acid damage and infl ammation in Wistar rats

Rev. Nutr. (Online); 31 (3), 2018
ABSTRACT Objective Nutritional diseases such as metabolic syndrome, cardiovascular disorder, chronic inflammation or even cancer are observed in people who sustain their lifestyle by Western diet due to high calorie intake. The origin of these diseases are the degraded deoxyribonucleic acid structure. I...

Mixed infection and two different resistance profiles of Treponema pallidum to macrolides identified in some clinical specimens of the same patient

Syphilis represents a global public health problem. The resistance of Treponema pallidum to macrolides is related to the mutation in the 23S rRNA gene (A2058G). We reported a case of secondary syphilis in a 52-year-old man presenting two profiles: the first one of susceptibility, and the other one of res...

Detection and molecular characterization of Cryptosporidium spp. in captive canaries (Serinus canaria) using different diagnostic methods

Abstract This study used several diagnostic methods to examine the occurrence of and molecularly characterize Cryptosporidium spp. in captive canaries (Serinus canaria) in southern and southeastern Brazil. A total of 498 fecal samples were purified by centrifugal-flotation using Sheather's solution. Cryp...

Influence of genetic polymorphisms in genes of bone remodeling and angiogenesis process in the apical periodontitis

Braz. dent. j; 29 (2), 2018
Abstract Persistent apical periodontitis (AP) is a situation involving an inflammatory and immune response caused mainly by anaerobic polymicrobial infection of the root canal system and the outcome and follow-up of the root canal treatment has been reported as intimately related to host response. The ap...