Abstract Objective Schizophrenia is a complex and chronic psychiatric disorder. In recent years, studies have found glutamatergic system participation in its etiopathogenesis, especially through aberrant NMDA receptors functioning. Thus, drugs that modulate this activity, as amantadine and memantine, co...
Com a Reforma Psiquiátrica, os familiares passaram a ser considerados protagonistas nos cuidados dos pacientes psiquiátricos. O presente estudo teve como objetivo investigar a experiência emocional de familiares cuidadores de pacientes psiquiátricos internados. Para isso, foram realizadas entrevistas...
Background Concurrence of substance use disorders (SUDs) is high in individuals with psychiatric illnesses; more importantly, individuals with both disorders (dual diagnosis) have more severe symptoms. Psychiatric disorders have been proposed to share a genetic susceptibility with SUDs. To explore this s...
O artigo tem como objetivo identificar por que, de acordo com Freud, a transferência de pacientes
psicóticos é inadequada para a clínica analítica. Descobrimos que essa afirmativa tem relação com o mecanismo de defesa empregado pelo psicótico que, diante de uma frustraç...
Abstract Background The Brief Negative Symptom Scale (BNSS) assesses the presence and intensity of negative symptoms in schizophrenia. Objectives This study aimed to carry out the BNSS cross-cultural adaptation to the Brazilian Portuguese language and verify its content validity and reliability. Met...
Abstract Background Schizophrenia (SCZ) and dementia, often related, are two of the most common neuropsychiatric diseases; epidemiological studies have shown that SCZ patients present a 2-fold increased risk for dementia compared to non-schizophrenic individuals. We explored the presence of rare and nov...
Abstract Introduction Schizophrenia is a severe mental disorder. While some antipsychotic medications have demonstrated efficacy in treating positive symptoms, there is no widely recognized treatment for negative symptoms, which can cause significant distress and impairment for patients with schizophre...
