ABSTRACT BACKGROUND There is evidence that shows that calcineurin inhibitors may be useful for the treatment of severe ulcerative colitis. However, evidence regarding the efficacy of tacrolimus for remission induction in this setting is scarce. OBJECTIVE To develop a systematic review on the existing...
ABSTRACT Purpose: To assess the efficacy of monotherapy using tacrolimus eye drops versus sodium cromoglycate for the treatment of vernal keratoconjunctivitis (VKC). Methods: Randomized double-masked controlled trial comparing the efficacy of tacrolimus 0.03% eye drops t.i.d. (Group 1) with sodium crom...
Conjuntivitis Alérgica/tratamiento farmacológico,
Conjuntivitis Alérgica/patología,
Cromolin Sódico/uso terapéutico,
Método Doble Ciego,
Inmunosupresores/uso terapéutico,
Soluciones Oftálmicas/uso terapéutico,
Índice de Severidad de la Enfermedad,
Estadísticas no Paramétricas,
Tacrolimus/uso terapéutico,
Factores de Tiempo,
Resultado del Tratamiento,
Agudeza Visual
Abstract Introduction: Immunosuppression of T lymphocytes is required for preventing acute rejection after transplantation and for the treatment of chronic autoimmune and inflammatory diseases. The laboratory monitoring for this therapy is the measurement of T cells by immunophenotyping, aiming the targ...
Abstract Calcineurin inhibitors (CNIs) are used widely for maintenance immunosuppression in renal transplant recipients. However, their side effect profile has led researchers to attempt to find safer alternatives that can maintain effective long-term immunosuppression with less toxicity. Belatacept is a...
Fluxá, Daniela;
Ibáñez, Patricio;
Flores, Lilian;
Figueroa, Carolina;
Lubascher, Jaime;
Kronberg, Udo;
Simian, Daniela;
Pizarro, Gonzalo;
Toche, Paola;
Quera, Rodrigo.
Anti-tumor necrosis factor-α (TNF) agents have dramatically changed the management of Crohns Disease (CD). However, a significant number of these patients do not respond at all or cease to respond to antibodies against TNF. In this clinical situation, the options include intensification of anti-TN...
Abstract: Acute hepatitis E is becoming increasingly recognised in Europe with up to 40% of the population in Southern France being exposed to the virus, which is harboured in pigs. Patients with known liver disease may present with acute hepatitis E and present a diagnostic challenge. For example patien...
Hepatitis E/diagnóstico,
Hepatitis Autoinmune/diagnóstico,
Enfermedad Aguda,
Enfermedad Crónica,
Diagnóstico Diferencial,
Progresión de la Enfermedad,
Quimioterapia Combinada,
Hepatitis E/inmunología,
Hepatitis E/virología,
Hepatitis Autoinmune/tratamiento farmacológico,
Hepatitis Autoinmune/inmunología,
Inmunosupresores/uso terapéutico,
Valor Predictivo de las Pruebas
O aprimoramento das técnicas analíticas viabilizou a metabolômica, uma área da ciência que busca compreender, de forma comparativa, os metabólitos envolvidos nas vias bioquímicas. A metabolômica está inserida no contexto das "ômicas", que teve início na "Era Genômica", a qual permitiu a ident...
RESUMO Objetivo Identificar como os cuidados clínicos e educativos de enfermagem, fundamentados na Teoria Human Becoming, contribuem para o processo de transcendência das pessoas transplantadas cardíacas na busca do bem viver. Método Pesquisa-intervenção desenvolvida com quatro transplantados c...
Brasil,
Toma de Decisiones,
Dieta,
Rechazo de Injerto,
Trasplante de Corazón/enfermería,
Trasplante de Corazón/psicología,
Trasplante de Corazón/rehabilitación,
Imaginación,
Inmunosupresores/uso terapéutico,
Atención de Enfermería/psicología,
Teoría de Enfermería,
Educación del Paciente como Asunto,
Satisfacción del Paciente,
Autonomía Personal,
Investigación Cualitativa,
Calidad de Vida,
Valores Sociales,
Centros de Atención Terciaria
Autoimmune hepatitis (AIH) is a liver disease of unknown etiology, with a breakdown in peripheral selftolerance against hepatocytes with both genetic and environmental factors involved. It is characterized by
an immune mediated liver injury, with detectable autoantibodies, elevated levels of immunoglobul...
Hepatitis Autoinmune/diagnóstico,
Hepatitis Autoinmune/tratamiento farmacológico,
Evolución Clínica,
Inmunosupresores/uso terapéutico,
Corticoesteroides/uso terapéutico,
Corticoesteroides/efectos adversos,
Azatioprina/efectos adversos,
Azatioprina/uso terapéutico,
Hepatitis Autoinmune/etiología,
Factores Biológicos/uso terapéutico,
Inhibidores de la Calcineurina/uso terapéutico,
Ácido Micofenólico/uso terapéutico
