Resumo: O objetivo deste trabalho é analisar o efeito da maturação sexual sobre os fenótipos corporais gerados por análise multivariada do estado nutricional de adolescentes. Este é um estudo transversal e a amostra foi composta por 833 adolescentes escolares de 10 a 15 anos, selecionados por amost...
Abstract INTRODUCTION: Pseudomonas aeruginosa is an opportunistic pathogen associated with healthcare-related infections, affecting mainly patients with underlying diseases and immunosuppression. This microorganism has several virulence mechanisms that favour its pathogenesis, including the production o...
RESUMO Objetivo Verificar se existem diferenças em pacientes com doença pulmonar obstrutiva crônica (DPOC) fenótipos exacerbador e não exacerbador submetidos a um programa de reabilitação pulmonar (PRP). Métodos Estudo retrospectivo de vida real que incluiu pacientes com DPOC da rede pública d...
Abstract The aim of our study was to isolate populations of keratinocyte stem cells based on the expression of cell surface markers and to investigate whether the culture could affect their phenotype. keratinocytes from human oral mucosa were sorted based on the expression of the epithelial stem cell mar...
Citometría de Flujo/métodos,
Células Epiteliales/citología,
Separación Celular/métodos,
Técnicas de Cultivo de Célula/métodos,
Biomarcadores/análisis,
Antígenos CD/análisis,
Queratinocitos/citología,
Mucosa Bucal/citología,
Proteínas del Tejido Nervioso/análisis,
Fenotipo,
Receptores de Factor de Crecimiento Nervioso/análisis,
Receptores de Transferrina/análisis,
Reproducibilidad de los Resultados,
Células Madre/citología
RESUMO Objetivo Avaliar se existe associação entre a presença de disfagia orofaríngea e a frequência de exacerbações em pacientes com doença pulmonar obstrutiva crônica (DPOC). Métodos Estudo transversal, para o qual foram recrutados pacientes com DPOC (Volume expiratório forçado no 1º seg...
BACKGROUND: Rice is the staple food of many people around the world. However, most rice varieties, especially widely grown indica varieties and hybrids, are sensitive to cold stress. In order to provide a basis for the utilization of a common wild rice (CWR, Oryza rufipogon Griff.) named 'Chaling' CWR in...
Abstract The relationship between periodontitis and the pathogenesis of other inflammatory diseases, such as diabetes, rheumatoid arthritis and obesity has been an important topic of study in recent decades. The Th17 pathway plays a significant role in how local inflammation can influence systemic inflam...
Estudios de Casos y Controles,
Periodontitis Crónica/inmunología,
Periodontitis Crónica/patología,
Citometría de Flujo,
Gingivitis/inmunología,
Gingivitis/patología,
Interleucina-23/sangre,
Índice Periodontal,
Fenotipo,
Receptores de Interleucina/sangre,
Estadísticas no Paramétricas,
Encuestas y Cuestionarios,
Células Th17/inmunología,
Células Th17/patología
ABSTRACT Objective: To identify phenylalanine hydroxylase (PAH) mutations in patients with phenylketonuria (PKU) from the Newborn Screening Service in Mato Grosso, Midwest Brazil. Methods: This is a cross-sectional descriptive study. The sample consisted of 19 PKU patients diagnosed by newborn screen...
Alelos,
Empalme Alternativo,
Brasil,
Estudios Transversales,
Análisis Mutacional de ADN/métodos,
Genotipo,
Mutación Missense,
Tamizaje Neonatal,
Fenotipo,
Fenilalanina Hidroxilasa/genética,
Fenilcetonurias/genética,
Polimorfismo de Longitud del Fragmento de Restricción
SUMMARY OBJECTIVE Glioblastoma (GBM) is a common type of cancer with high mortality. Epithelial to mesenchymal transition (EMT) plays a vital role in the development of glioblastoma. The aim of this study is to evaluate the role of miR-125a-5p in glioblastoma and in the tumorigenesis of chemotherapeuti...
Proliferación Celular,
Transición Epitelial-Mesenquimal/genética,
Regulación Neoplásica de la Expresión Génica,
Genes Relacionados con las Neoplasias,
Glioblastoma/genética,
Glioblastoma/patología,
MicroARNs/genética,
MicroARNs/metabolismo,
Células Madre Neoplásicas/patología,
Fenotipo,
ARN Mensajero/genética,
ARN Mensajero/metabolismo
