Results: 269

Glycemic behavior in patients with type 2 diabetes during a short period of a combined training program

Motriz (Online); 24 (3), 2018
The present study investigated the behavior of glycemia in subjects with type 2 diabetes (T2DM) during 36 sessions of a combined training program. Methods: This is a single arm clinical study with 20 patients with T2DM submitted to combined exercise training (strength and aerobic exercise). The session...

Exenatide ameliorates hepatic steatosis and attenuates fat mass and FTO gene expression through PI3K signaling pathway in nonalcoholic fatty liver disease

Braz. j. med. biol. res; 51 (8), 2018
Non-alcoholic fatty liver disease (NAFLD) is a common disease associated with metabolic syndrome and can lead to life-threatening complications like hepatic carcinoma and cirrhosis. Exenatide, a glucagon-like peptide-1 (GLP-1) receptor agonist antidiabetic drug, has the capacity to overcome insulin resis...

ACE gene dosage determines additional autonomic dysfunction and increases renal angiotensin II levels in diabetic mice

Clinics; 73 (), 2018
OBJECTIVES: The present study aimed to investigate cardiovascular autonomic modulation and angiotensin II (Ang II) activity in diabetic mice that were genetically engineered to harbor two or three copies of the angiotensin-converting enzyme gene. METHODS: Diabetic and non-diabetic mice harboring 2 or 3 ...

Factors associated with complex surgical wounds in breast and abdomen: a case-control observational study

ABSTRACT Objective: to identify factors associated with complex surgical wounds in the breasts and abdomen in outpatients. Method: observational case-control study involving 327 patients, distributed into 160 cases (complex surgical wound) and 167 controls (simple surgical wound). Data were extracted f...

Insulin resistance is increased in adult patients with dermatomyositis

OBJECTIVE: To evaluate insulinemia in glucocorticoid naïve patients with dermatomyositis and to evaluate insulin resistance using the homeostatic model assessment of insulin resistance (HOMA2-IR). METHODS: This cross-sectional study included 25 dermatomyositis, non-diabetic glucocorticoid naïve patien...

Type-2 diabetes alters the basal phenotype of human macrophages and diminishes their capacity to respond, internalise, and control Mycobacterium tuberculosis

Mem. Inst. Oswaldo Cruz; 113 (4), 2018
BACKGROUND Type 2 diabetes (T2D) is a risk factor for the development of tuberculosis (TB), although the associated mechanisms are not known. OBJECTIVES To study the association between T2D and the basal phenotype of macrophages, and their immune response to Mycobacterium tuberculosis (Mtb) infection....

Diabetes remission rate in different bmi grades following roux-en-y gastric bypass

ABCD (São Paulo, Impr.); 31 (1), 2018
ABSTRACT Background: Type 2 diabetes mellitus has a high long-term remission rate after laparoscopic Roux-en-Y gastric bypass (LRYGB), but few studies have analyzed patients with BMI<35 kg/m2. Aim: To compare glycemic control after LRYGB between BMI 30-35 kg/m2 (intervention group or IG) and >3...

Food intake evaluation during the first year of postoperative of patients with type 2 diabetes mellitus or glycemic alteration submitted to roux-en-y gastric bypass

ABCD (São Paulo, Impr.); 31 (2), 2018
ABSTRACT Background : Obesity is one of the main causes of glycemic change. Failure of clinical obesity treatment may lead to an increase in bariatric surgery. Dietary guidance, in conjunction with disabsorptive and hormonal factors resulting from the anatomical and physiological changes provoked by the...

Hiperglucemia subclínica en adultos mayores basada en el proyecto SABE (Salud, Bienestar y Envejecimiento) de San Luis Potosí, México
Subclinical hyperglycemia in older adults based on the SABE (Health, Well-being and Aging) project in San Luis Potosí, Mexico

Rev. med. interna Guatem; 22 (1), 2018
La interacción de varios factores asociados al envejecimiento contribuye a las alteraciones en la tolerancia a la glucosa en este grupo de edad. Es necesario conocer la prevalencia de hiperglucemia subclínica en adultos mayores de 60 años del Estado de San Luis Potosí. Material y métodos: se realiz...

Educational Workshop using games improves self-monitoring of blood glucose among children

ABSTRACT Objective: to evaluate the effectiveness of an educational workshop using games to improve self-monitoring of blood glucose techniques for school children with type 1 diabetes. Method: a quasi-experimental study was conducted with school children who attended two outpatient clinics of a univer...