Background: Physical exercise may modify biologic stress responses. Objective: To investigate the impact of exercise training on vascular alterations induced by acute stress, focusing on nitric oxide and cyclooxygenase pathways. Method: Wistar rats were separated into: sedentary, trained (60-min swimming...
Although numerous studies investigate sensory recovery of the hind paw of the rat after nerve damage, still no comprehensive overview of its normal innervation is present in the literature. We investigated the morphometry of myelinated fibers in the sural and saphenous nerves and analyzed their size dist...
BACKGROUND AND OBJECTIVES: Tramadol is known as a central acting analgesic drug, used for the treatment of moderate to severe pain. Local analgesic effect has been demonstrated, in part due to local anesthetic-like effect, but other mechanisms remain unclear. The role of peripheral opioid receptors in th...
Analgésicos Opioides/administración & dosificación,
Analgésicos Opioides/farmacología,
Modelos Animales de Enfermedad,
Hiperalgesia/tratamiento farmacológico,
Inyecciones,
Inyecciones Intravenosas,
Naloxona/administración & dosificación,
Naloxona/farmacología,
Dolor Postoperatorio/tratamiento farmacológico,
Ratas Wistar,
Receptores Opioides/efectos de los fármacos,
Receptores Opioides/metabolismo,
Factores de Tiempo,
Tramadol/administración & dosificación,
Tramadol/farmacología
The objective of this study was to evaluate the long term nociceptive response determined by use of two general anesthetics, one intravenous and the other inhalatory, in young animals. In the first experiment, the animals of 21 days of age were divided into control (saline) and thiopent...
BACKGROUND: The mechanism by which high-voltage electrical stimulation (HVPC) acts on edema reduction is unknown. OBJECTIVE: To assess the effect of HVPC with negative polarity (-) applied to the ankle of rats with acute joint inflammation. METHOD: Sixty-four rats were divided into four groups (n=16): in...
Artritis/sangre,
Artritis/terapia,
Edema/sangre,
Edema/terapia,
Terapia por Estimulación Eléctrica/métodos,
Histamina/sangre,
Dolor/sangre,
Albúmina Sérica/análisis,
Enfermedad Aguda,
Artritis/complicaciones,
Edema/etnología,
Dolor/etiología,
Ratas Wistar,
Distribución Aleatoria
The present study was to investigate the effects of visfatin on the morphological structure and function of the rat uterus during inflammation. The expression and distribution of visfatin, morphological structure, eosinophils (EOS), myeloperoxidase (MPO) and cytokines in the uterus of the LPS-induced rat...
A indução do diabetes mellitus com substâncias citotóxicas como a Aloxana em animais de experimentação tem sido amplamente empregada com a finalidade de desenvolver estudos voltados ao tratamento desta patologia, mas alguns pesquisadores apontam dificuldades na indução e de manter os a...
Bauhinia forficata Link, popularly known as pata-de- vaca, unha-de-vaca, casco-de-vaca, has been widely used in traditional medicine to treat several diseases. Leaves of B. forficata are used in popular medicine as a diuretic, hypoglycemic, tonic and cleanser, and to combat elephantiasis. However, despit...
BACKGROUND AND OBJECTIVE: Previous studies regarding the effects of some local anaesthetics have suggested that these agents can cause genetic damage. However, they have not been tested for genotoxicity related to repetitive administration. The aim of this study was to evaluate the genotoxic potential of...
Objetivo Verificar a funcionalidade por meio da força muscular de preensão em animais com obesidade induzida por glutamato monossódico (MSG) e animais controle, que sofreram compressão do nervo mediano direito, tendo como tratamento a natação com carga. Métodos Ratos Wistar neonatos durante os pri...
