Results: 1740

Absorption mechanism of three curcumin constituents through in situ intestinal perfusion method

Braz. j. med. biol. res; 50 (11), 2017
This study aimed to investigate the absorption mechanism of three curcumin constituents in rat small intestines. Self-emulsification was used to solubilize the three curcumin constituents, and the rat in situ intestinal perfusion method was used to study factors on drug absorption, including drug mass co...

Protective effects of deferasirox and N-acetyl-L-cysteine on iron overload-injured bone marrow

Braz. j. med. biol. res; 50 (12), 2017
Using an iron overload mouse model, we explored the protective effect of deferasirox (DFX) and N-acetyl-L-cysteine (NAC) on injured bone marrow hematopoietic stem/progenitor cells (HSPC) induced by iron overload. Mice were intraperitoneally injected with 25 mg iron dextran every 3 days for 4 weeks to est...

Perceived Stress Scale: confirmatory factor analysis of the PSS14 and PSS10 versions in two samples of pregnant women from the BRISA cohort

This study aimed to assess the dimensional structure, reliability, convergent validity, discriminant validity, and scalability of the Perceived Stress Scale (PSS). The sample consisted of 1,447 pregnant women in São Luís (Maranhão State) and 1,400 in Ribeirão Preto (São Paulo State), Brazil. The 14 ...

Relação entre consumo alimentar de vitaminas e minerais, índice de massa corporal e circunferência da cintura: um estudo de base populacional com adultos no Sul do Brasil

Resumo: O objetivo do estudo foi investigar a associação entre o consumo alimentar inadequado de micronutrientes e indicadores de obesidade geral e abdominal. Análise transversal, da segunda onda do estudo longitudinal EpiFloripa Adultos, incluindo 1.222 indivíduos de 22-63 anos, residentes em Floria...

O tempo de percurso a cidades polos regionais influencia na mortalidade em pequenos municípios gaúchos?

Resumo: O presente estudo objetiva responder se o tempo de viagem a municípios polos regionais possui efeito na taxa de óbitos por causas evitáveis (TOCE) e na taxa bruta de mortalidade padronizada (TBMP) em municípios com até 5 mil habitantes do Rio Grande do Sul, Brasil. Sem a utilização de vari...

Validade da informação sobre o peso ao nascer para estudos fundamentados na programação fetal

Peso ao nascer é uma informação essencial nos estudos de programação fetal e, em geral, obtida retrospectivamente. No Sistema de Informações sobre Nascidos Vivos (SINASC), peso ao nascer é uma informação válida, mas nem sempre acessível. Objetivou-se estabelecer um algoritmo para seleção da...

Occupational exposure to hydrogen cyanide during large-scale cassava processing, in Alagoas State, Brazil

Abstract: The cassava roots used for flour production contain high amounts of cyanogenic glycosides and are, therefore, potential hydrogen cyanide (HCN) releasers. This fact is the cause of an increasing health concern in the sector of cassava processing. Brazilian workers engaged in the flour production...

PAR-2 expression in the gingival crevicular fluid reflects chronic periodontitis severity

Abstract Recent studies investigating protease-activated receptor type 2 (PAR-2) suggest an association between the receptor and periodontal inflammation. It is known that gingipain, a bacterial protease secreted by the important periodontopathogen Porphyromonas gingivalis can activate PAR-2. Previous st...

The efficacy of low-level 940 nm laser therapy with different energy intensities on bone healing

Abstract The aim of this study was to evaluate the efficacy of low-level 940 nm laser therapy with energy intensities of 5, 10 and 20 J/cm2 on bone healing in an animal model. A total of 48 female adult Wistar rats underwent surgery to create bone defects in the right tibias. Low-level laser therapy (LLL...

Short implants to support mandibular complete dentures - photoelastic analysis

Abstract This study evaluated the stress behavior around short implants in edentulous atrophic mandibles. Six groups included implants with two diameters regular and wide (4 and 5 mm) and three lengths (5, 7 and 9 mm) as follows: Ci9 (9 x 4 mm), Ci7 (7 x 4 mm), Ci5 (5 x 4 mm), Wi9 (9 x 5 mm), Wi7 (7 x 5 ...