Results: 256

Evaluación de la recurrencia de tumores musculoesqueléticos mediante gammagrafía complementada con SPECT/CT con talio-201 en población pediátrica

Resumen Introducción: Los estudios de imagen, como la tomografía simple y contrastada, son la primera aproximación diagnóstica para detectar la recurrencia de tumores musculoesqueléticos. El objetivo de este estudio retrospectivo fue demostrar la utilidad de la gammagrafía acoplada a tomografía ...

Outcomes of patients with bone metastases from differentiated thyroid cancer

ABSTRACT Objective Bone metastases (BM) from differentiated thyroid cancer (DTC) are associated with poor survival rates. Due to the low frequency of this entity, we performed a multicentric retrospective study that aimed to evaluate the presentation, outcome and causes of death in this population. Sub...

Epidemiological characteristics of patients with pelvic tumors submitted to surgical treatment

ABSTRACT Objective: Describe the epidemiological profile of patients with primary or secondary neoplastic lesions in the pelvis who required a surgical procedure such as hemipelvectomy. Methods: This study retrospectively evaluated 69 patients located in the database of a São Paulo educational insti...

Osteocondroma como hallazgo Incidental en Úlcera Varicosa Sobreinfectada en miembro inferior

El osteocondroma es la lesión tumoral más frecuente del hueso. Éste presenta características radiológicas patognomónicas con continuidad cortical y medular, con lesión exofítica iniciada en metáfisis, protruyendo hasta la diáfisis de huesos largos, con predominio en la porción distal del fému...

Instrumentación anterior y posterior para tratamiento de fractura por Metástasis Vertebral

Las fracturas tumorales en columna vertebral son parte de la etiología de las fracturas patológicas a este nivel, que por edad de presentación, así como la clínica observada puede otorgar directrices del tipo de tumor que afecta al esqueleto axial. Por tanto, resulta importante su identificación, c...

Análise bioética do uso de protocolos clínicos de oncologia em adolescentes

Os protocolos clínicos são recomendações normativas atreladas a várias abordagens terapêuticas que tomaram por bases os estudos que têm a medicina baseada em evidências para compor as suas estruturações. Nesse contexto, os protocolos clínicos em adultos são utilizados em várias especialidade...

The diagnosis and treatment of tibial intercondylar chondroblastoma

Clinics; 73 (), 2018
OBJECTIVES: To investigate the diagnosis and treatment of tibial intercondylar chondroblastoma. METHODS: We retrospectively analyzed the diagnosis and treatment of 12 patients with tibial intercondylar chondroblastoma admitted to the orthopedics department from May 2011 to February 2016; among them were...

Astragalus polysaccharides decrease proliferation, migration, and invasion but increase apoptosis of human osteosarcoma cells by up-regulation of microRNA-133a

Braz. j. med. biol. res; 51 (12), 2018
Osteosarcoma (OS) has a high incidence, malignity, and frequency of recurrence and metastasis. In this study, we aimed to explore the potential anti-cancer effects of Astragalus polysaccharides (APS) on human OS MG63 cells as well as underlying mechanisms. Viability of MG63 cells was assessed by CCK-8 as...

Metástases pulmonares em crianças: estamos operando desnecessariamente?

Rev. Col. Bras. Cir; 45 (3), 2018
RESUMO Objetivo: determinar, em pacientes pediátricos portadores de neoplasias malignas, as características de nódulos pulmonares identificados à tomografia computadorizada, capazes de diferenciar nódulos benignos de metástases. Métodos: estudo retrospectivo de pacientes submetidos a ressecçõe...

Up-regulated expression of CD147 gene in malignant bone tumor and the possible induction mechanism during osteoclast formation

Braz. j. med. biol. res; 51 (9), 2018
It is increasingly evident that the microenvironment of bone can influence cancer phenotype in many ways that favor growth in bone. CD147, a transmembrane protein of the immunoglobulin (Ig) superfamily, was identified independently in different species and has many designations across different species. ...