Dantas, L L S F R;
Fonseca, A G;
Pereira, J R;
Furtado, A A;
Gomes, P A T M;
Fernandes-Pedrosa, M F;
Leite, A C L;
Rêgo, M J B M;
Pitta, M G R;
Lemos, T M A M.
Several isatin derivatives have shown important biological activities, which have attracted interest from researchers. For this reason, the present study aimed to evaluate the anti-inflammatory and antinociceptive effects of the isatin derivative (Z)-2-(5-chloro-2-oxoindolin-3-ylidene)-N-phenyl-hydrazine...
BACKGROUND: Psoriasis is a common chronic inflammatory skin disease. Keratinocytes hyperproliferation and excessive inflammatory response contribute to psoriasis pathogenesis. The agents able to attenuate keratinocytes hyper-proliferation and excessive inflammatory response are considered to be potential...
Abstract Chronic inflammation is a common indication of several diseases, e.g. asthma, chronic obstructive pulmonary disease (COPD), atherosclerosis, etc. Benzimidazole derivatives are preferable compounds to design new analgesic and anti-inflammatory substances due to their unique biological features. W...
O objetivo deste estudo foi realizar o levantamento bibliográfico de artigos científicos e ensaios clínicos sobre a utilização
de anticorpos monoclonais, imunomoduladores e anti-inflamatórios como possíveis alternativas terapêuticas para uso em
pacientes com COVID-19, com ênfase nos mecanismos...
COVID-19/tratamiento farmacológico,
Anticuerpos Monoclonales/uso terapéutico,
Factores Inmunológicos/uso terapéutico,
Antiinflamatorios/uso terapéutico,
Ensayos Clínicos como Asunto,
Eficacia,
COVID-19/inmunología,
COVID-19/fisiopatología,
COVID-19/complicaciones,
Anticuerpos Monoclonales/farmacología,
Anticuerpos Monoclonales/inmunología,
Anticuerpos Monoclonales/efectos adversos,
Factores Inmunológicos/farmacología,
Factores Inmunológicos/inmunología,
Factores Inmunológicos/efectos adversos,
Antiinflamatorios/farmacología,
Antiinflamatorios/inmunología,
Antiinflamatorios/efectos adversos
Abstract Purpose: In laparoscopic incisional hernia repair, meshes with a tissue-separating barrier are positioned intraperitoneally. Despite this property, the close contact between mesh and viscera involves a risk of adhesion formation. Some natural products, such as red propolis (RP), could reduce th...
Abstract Purpose To investigate the effect of growth arrest-specific protein 6 (Gas6) on acute liver injury in mice and related mechanisms. Methods Thirty C57BL/6 (6-8 weeks old) mice were randomly divided into control, LPS/D-GalN, and LPS/D-GalN+Gas6 groups (10 mice in each group). The LPS/D-GalN gr...
Baddini-Martinez, José;
Ferreira, Juliana;
Tanni, Suzana;
Alves, Luis Renato;
Cabral Junior, Benedito Francisco;
Carvalho, Carlos Roberto Ribeiro;
Cezare, Talita Jacon;
Costa, Claudia Henrique da;
Gazzana, Marcelo Basso;
Jezler, Sérgio;
Kairalla, Ronaldo Adib;
Kawano-Dourado, Leticia;
Lima, Mariana Silva;
Mancuzo, Eliane;
Moreira, Maria Auxiliadora Carmo;
Rodrigues, Marcelo Palmeira;
Rodrigues, Silvia Carla Sousa;
Rubin, Adalberto Sperb;
Rufino, Rogério Lopes;
Steidle, Leila John Marques;
Storrer, Karin;
Baldi, Bruno Guedes.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a form of chronic interstitial lung disease of unknown cause, which predominantly affects elderly men who are current or former smokers. Even though it is an uncommon disease, it is of great importance because of its severity and poor prognosis. In recent d...
ABSTRACT Objective: To report the case of a child who developed acute respiratory distress syndrome (ARDS) from a pulmonary infection by adenovirus. Case description: A female patient aged 2 years and 6 months, weighting 10,295 grams developed fever, productive cough and vomiting, later on progressin...
Adenoviridae/aislamiento & purificación,
Infecciones por Adenovirus Humanos/complicaciones,
Antiinflamatorios/uso terapéutico,
Ecocardiografía,
Oxigenación por Membrana Extracorpórea/métodos,
Ventilación de Alta Frecuencia/métodos,
Intubación Intratraqueal,
Metilprednisolona/uso terapéutico,
Neumonía Viral/complicaciones,
Neumonía Viral/diagnóstico por imagen,
Posición Prona,
Síndrome de Dificultad Respiratoria/etiología,
Síndrome de Dificultad Respiratoria/terapia
A encefalite límbica vem sendo descrita como um distúrbio neurológico raro, que afeta seletivamente as estruturas do sistema
límbico. Clinicamente, é caracterizada como uma desordem
neurológica debilitante, que se desenvolve como encefalopatia
rapidamente progressiva, causada por inflamação en...
Encefalitis Límbica/diagnóstico por imagen,
Encefalitis Límbica/inmunología,
Autoinmunidad,
Epilepsia/tratamiento farmacológico,
Carbamazepina/uso terapéutico,
Anticonvulsivantes/uso terapéutico,
Confusión/etiología,
Encefalitis Límbica/complicaciones,
Paresia/etiología,
Disartria/etiología,
Parestesia,
Examen Neurológico,
Encefalitis Límbica/líquido cefalorraquídeo,
Tomografía Computarizada por Rayos X,
Espectroscopía de Resonancia Magnética,
Encefalitis Límbica/tratamiento farmacológico,
Prednisona/uso terapéutico,
Antiinflamatorios/uso terapéutico,
Encefalitis Límbica/virología,
Hiponatremia,
Encefalitis Límbica/sangre,
Electroencefalografía
Objective: To compare the anti-inflammatory effectiveness of dexa-methasone as pre-surgical and post-surgical therapy in mandibular third molar surgery. Materials and methods: Randomized clinical trial conducted in 60 patients in need of mandibular third molar extraction, ages ranging from 16 to 35 years...
