Results: 363

Análise geoespacial da distribuição de flebotomíneos e cães com leishmaniose visceral no município de Angra dos Reis/RJ /

A Leishmaniose Visceral (LV) é causada pelo protozoário da espécie Leishmania (Leishmania) infantum, zoonose que tem incriminado como principal vetor Lutzomyia longipalpis e tem o cão como principal reservatório doméstico. O Sensoriamento Remoto (SR) e o Sistema de Informações Geográficas (SIG) ...

Estudo de alterações celulares e moleculares em Leishmania (leishmania) infantum tratada com fármacos anti-histamínicos

A leishmaniose visceral (LV) é uma doença infecciosa sistêmica, causada pelos parasitos protozoários do gênero Leishmania, endêmica em países tropicais e subtropicais. Por acometer principalmente populações de baixa renda em países em desenvolvimento e subdesenvolvidos, a leishmaniose se encaix...

Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae)

Visceral leishmaniasis is a complex neglected tropical disease caused by Leishmania donovani complex. Its current treatment reveals strong limitations, especially high toxicity. In this context, natural products are important sources of new drug alternatives for VL therapy. Therefore, the antileishmanial...

Leishmaniose visceral no estado de São Paulo, Brasil: avaliação das ações de vigilância e controle no Centro-Oeste Paulista, de 1999 a 2018, região endêmica para Leishmaniose Tegumentar

A expansão geográfica da leishmaniose visceral (LV) no Brasil está associada ao processo de urbanização da doença envolvendo a migração da população do campo para os centros urbanos; à adaptação do vetor ao ambiente domiciliar; e à presença do cão como reservatório doméstico. Essa enfer...

Where, when, and how the diagnosis of human visceral leishmaniasis is defined: answers from the Brazilian control program

Mem. Inst. Oswaldo Cruz; 114 (), 2019
BACKGROUND Timely diagnosis is recommended by the Brazilian Visceral Leishmaniasis (VL) Surveillance and Control Program to reduce case fatality. Attempts at assessing this topic in Brazil are scarce. OBJECTIVE This study aimed to describe where, when, and how the diagnosis of VL has been performed in...

Prevalence of HIV and associated factors among visceral leishmaniasis cases in an endemic area of Northeast Brazil

Abstract INTRODUCTION Cases of visceral leishmaniasis (VL) and HIV co-infection have increased worldwide. We investigated the prevalence of HIV and associated factors among VL patients in Sergipe state, Brazil. METHODS We conducted a population-based study of all cases of VL and HIV reported in Sergi...

Evaluation of DPP® and SNAP® Rapid Tests for diagnosis of Leishmania infantum canine infections

Abstract INTRODUCTION: Visceral leishmaniasis is a disease that affects humans, wildlife, and domestic species. Since dogs play a key role in urban Leishmania spp. transmission, the Brazilian government maintains the Monitoring and Control Program of Visceral Leishmaniasis (VLMCP) in endemic regions, w...

Cost-effectiveness analysis of diagnostic-therapeutic strategies for visceral leishmaniasis in Brazil

Abstract INTRODUCTION: Visceral leishmaniasis (VL) is fatal if not diagnosed and treated. This study aimed to estimate the cost-effectiveness of diagnostic-therapeutic alternatives for VL in Brazil. METHODS: A decision model estimated the life expectancy and costs of six diagnostic-therapeutic strate...

Risk mapping of visceral leishmaniasis in Brazil

Abstract INTRODUCTION: Brazil experiences a large number of visceral leishmaniasis (VL) cases. Our objective was to examine both spatial patterns of dispersion and space-time trends for this disease. METHODS: We used all autochthonous confirmed cases of VL in Brazil from 2001 to 2017. RESULTS: Throu...