Results: 3610

Impacto del uso de esteroides en el tratamiento de los pacientes con neumonía grave adquirida en la comunidad
The impact of steroids usage in the treatment of patients with severe community-acquired pneumonia

Rev. medica electron; 40 (6), 2018
RESUMEN Introducción: a neumonía adquirida en la comunidad constituye un importante problema de salud a nivel global. Es la tercera causa de muerte globalmente. EL mejor tratamiento para estos pacientes todavía no está bien establecido. Objetivo: evaluar el impacto en la mortalidad del uso de los ...

Características clínicas y pronóstico de pacientes con cáncer de mama HER2 positivo avanzado, en la era antes y después de terapias anti-HER2

Rev. méd. Chile; 146 (10), 2018
Background: HER2+ breast cancer (BC) subtype overexpresses the Human Epidermal growth factor Receptor type-2 (HER2) and is characterized by its aggressiveness and its high sensitivity to monoclonal antibody-based HER2-targeted therapies. Aim: To assess the prognosis and evaluate the impact of novel anti...

Obesidad y mortalidad en los pacientes con insuficiencia cardiaca crónica
Obesity and mortality in chronic heart failure patients

Rev. cuba. med; 57 (4), 2018
Introducción: La obesidad causa insuficiencia cardiaca por diferentes mecanismos que no se limitan a factores mediadores tradicionales. Esta se asocia a mecanismos inflamatorios, disfunción endotelial y factores trombogénicos. En prevención secundaria se observó un efecto inverso de la obesidad en ...

Evolución terapéutica de la hepatitis crónica por virus C
Therapeutic evolution of chronic hepatitis C virus

Rev. cuba. med; 57 (4), 2018
Escasas áreas geográficas escapan a la pandemia que representa la infección viral por virus C. Los porcentajes de evolución a la cronicidad son altos: entre 20-30 por ciento desarrollan cirrosis hepática y sus complicaciones dentro de 30 años. Se revisa el camino recorrido en la práctica asistenci...

The importance of intra-aortic pulse pressure after anterior ST-segment elevation myocardial infarction

Abstract Objective: To evaluate the association of pulse pressure (PP) with mortality and major adverse cardiac events (MACE) in one-year period after anterior ST-elevation myocardial infarction (A-STEMI). Methods: A total of 261 consecutive patients whose blood pressure was measured with the aid of a ...

The negative effect of mean perfusion pressure on the development of acute kidney injury after transcatheter aortic valve implantation

Abstract Objective: To evaluate the predictive value of mean perfusion pressure (mPP) in the development of acute kidney injury (AKIN) after transcatheter aortic valve implantation (TAVI). Methods: One hundred and forty seven consecutive patients with aortic stenosis (AS) were evaluated for this study ...

Risk factors for mortality in children with congenital heart disease delivered at a brazilian tertiary center

Abstract Objective: This study aims to investigate the incidence of postnatal diagnosis of congenital heart disease (CHD) and the predictive factors for hospital mortality. Methods: This retrospective cohort study was conducted at a Brazilian tertiary center, and data were collected from medical record...

Should sinus of valsalva be replaced in patients with dilated ascending aorta and aortic valve diseases?

Abstract Introduction: The aim of this study is to investigate the change in the dimension of sinus of Valsalva in patients who underwent supracoronary ascending aorta replacement with aortic valve replacement. Methods: A total of 81 patients who underwent supracoronary ascending aorta replacement with...

Distribution of molecular subtypes of advanced lung adenocarcinoma and clinical outcomes in a center of Argentina

Medicina (B.Aires); 78 (6), 2018
The prevalence of relevant oncogenic drivers in lung adenocarcinoma varies in our region and data on clinical outcomes is scarce. The objective of the study was to describe the prevalence of KRAS, BRAF and EGFR mutations and ALK translocations in patients with advanced lung adenocarcinoma, and to depict ...