Results: 3275

Cardioprotective effect of lipstatin derivative orlistat on normotensive rats submitted to cardiac ischemia and reperfusion

Acta cir. bras; 33 (6), 2018
Abstract Purpose: To evaluate in vivo animal model of cardiac ischemia/reperfusion the cardioprotective activity of pancreatic lipase inhibitor of the orlistat. Methods: Adult male Wistar rats were anesthetized, placed on mechanical ventilation and underwent surgery to induce cardiac I/R by obstructin...

Development of a model for laparoscopic cholecystectomy video assisted training. A randomized study

Acta cir. bras; 33 (6), 2018
Abstract Purpose: To identify the surgical trainee benefits through the use of video assisted training (VAT). Methods: Twelve cases of uncomplicated laparoscopic cholecystectomy (LC) were selected. Edited video segments focused on essential intra-operative anatomical structure identification and criti...

Effects of hypothermia on lung inflammation in a rat model of meconium aspiration syndrome

Acta cir. bras; 33 (6), 2018
Abstract Purpose: To evaluate the effects of hypothermia treatment on meconium-induced inflammation. Methods: Fifteen rats were instilled with human meconium (MEC, 1.5 mL/kg, 65 mg/mL) intratracheally and ventilated for 3 hours. Eight rats that were ventilated and not instilled with meconium served a...

Impact of 1 25(OH) 2 D 3 on TG content in liver of rats with type 2 diabetes

Acta cir. bras; 33 (6), 2018
Abstract Purpose: To evaluate the effects of 1,25 dihydroxy vitamin D3 (1,25(OH)2D3) on the content of triglyceride (TG), as well as on the gene and protein expressions of adiponectin receptor 2 (AdipoR2), p38 mitogen-activated protein kinase (P38MAPK), and lipoprotein lipase (LPL) in the liver of rats...

Antioxidant extract counteracts the effects of aging on cortical spreading depression and oxidative stress in the brain cortex

Acta cir. bras; 33 (6), 2018
Abstract Purpose: To investigate the effects of Murici extract on the brain excitability-dependent phenomenon known as cortical spreading depression (CSD) and on brain oxidative stress. Methods: Adult and aged Wistar rats were supplemented with murici extract (150 mg/kg/day or 300 mg/kg/day) by gavage...

Synergistic effect of honey and Nigella sativa on wound healing in rats

Acta cir. bras; 33 (6), 2018
Abstract Purpose: To investigate the therapeutic potential of honey, Nigella sativa (N. sativa) and their combination in rat model of excisional wound healing. Methods: A circular excision wound was established in the back region of 50 Wistar rats. Subsequently, they were divided into 5 groups and da...

The therapeutic effects of curcumin and capsaicin against cyclophosphamide side effects on the uterus in rats

Acta cir. bras; 33 (6), 2018
Abstract Purpose: To evaluate the impact of systemic cyclophosphamide treatment on the rat uterus and investigate the potential therapeutic effects of natural antioxidant preparations curcumin and capsaicin against cyclophosphamide side effects. Methods: A 40 healthy adult female Wistar albino rats w...

Interleukin-4 protects from chemotherapy-induced peripheral neuropathy in mice modal via the stimulation of IL-4/STAT6 signaling

Acta cir. bras; 33 (6), 2018
Abstract Purpose: To investigate the possible role of IL-4 signaling pathway in vincristine-induced peripheral neuropathy. Methods: The mouse model of vincristine-induced peripheral neuropathy and interleukin (IL)-4 knockout mice were utilized to investigate the possible role of IL-4 signaling pathwa...

An experimental study on the preventive effects of N-acetyl cysteine and ozone treatment against contrast-induced nephropathy

Acta cir. bras; 33 (6), 2018
Abstract Purpose: To compare the preventive effects of N-acetyl cysteine (NAC), ozone preconditioning and ozone treatment against contrast-induced nephropathy (CIN) in an experimental rat model. Methods: Thirty adult male Wistar rats were randomly distributed into five groups (n=6 for each group). Gro...

Validación de una técnica de Dot blot para la detección de Cercospora kikuchii en plantas de soja

Rev. argent. microbiol; 50 (2), 2018
Cercospora kikuchii, fitopatógeno usual en plantas de soja, ocasiona deterioro en la scosechas. Su identificación precoz y correcta evitaría el uso indebido de plaguicidas y permitiría iniciar un tratamiento adecuado. Una técnica rápida, económica y de fácil ejecución es el Dot blot, capaz de re...