Introdução: Autogerenciamento é um conceito atual que integra polÃticas públicas internacionais cujos modelos de atenção à saúde visam, dentre outros princÃpios, a potencialização da pessoa para assumir o protagonismo das práticas que favoreçam o bem-estar na vivência de uma situação crÃ...
Apesar da grande relevância médica e social, e por serem responsáveis por grande parte das mortes em paÃses subdesenvolvidos e em desenvolvimento as doenças negligenciadas (DN), ainda, não apresentam terapêutica eficaz. Dentre as diversas DN, doenças como a doença de Chagas, a Leishmaniose visce...
Preparaciones Farmacéuticas/administración & dosificación,
Enfermedades Desatendidas/complicaciones,
EspectroscopÃa de Protones por Resonancia Magnética/métodos,
EspectroscopÃa de Resonancia Magnética con Carbono-13,
Antineoplásicos/análisis,
Antiparasitarios/efectos adversos,
CromatografÃa LÃquida de Alta Presión/métodos,
Estrategias de Salud,
PaÃses en Desarrollo/clasificación,
Preparaciones Farmacéuticas/análisis,
Chalconas/efectos adversos
Gribner, Caroline;
Moura, Paula Francislaine;
Veiga, Andressa;
Gatto, Larissa Junqueira;
Santos, Nayana Cristina da Silva;
Marques, Francisco de Assis;
Zattoni, Ingrid;
Valdameri, Glaucio;
Dias, Josiane de Fatima Gaspari;
Miguel, Obdulio Gomes;
Zanin, Sandra Maria Warumby.
La composición quÃmica del aceite esencial obtenido de las ramas de Ocotea paranaensis se estudió por cromatografÃa de gases/espectrometrÃa de masas (CG/MS). Se identificaron veintisiete compuestos, que comprenden el 94,82% de los componentes totales. El aceite se caracterizó por una concentración...
El presente estudio tiene como objetivo explorar las posibles aplicaciones de los extractos de corteza y hoja de Blepharocalyx
cruckshanksii como agente citotóxico contra lÃneas celulares de cáncer in vitro ((MCF-7, PC-3 y HT-29) mediante el uso de ensayo de
sulforhodamine B (SRB). El ensayo de citoto...
Abstract Objective: To determine the occurrence and severity of oral mucositis (OM) and the factors associated with the onset of severe oral mucositis (SOM) in pediatric cancer patients. Material and Methods: This was a longitudinal and prospective study with 85 children and adolescents (aged 0 to 19 y...
ABSTRACT OBJECTIVE: To estimate the incidence and to evaluate risk factors for antineoplastic nausea and vomiting with high and moderate emetogenic chemotherapy in adult patients in the first treatment cycle. METHODS: Prospective cohort study with follow-up of 269 adults during the first cycle of antin...
Antieméticos/uso terapéutico,
Antineoplásicos/efectos adversos,
Antineoplásicos/uso terapéutico,
Brasil/epidemiologÃa,
Estudios de Cohortes,
Incidencia,
Persona de Mediana Edad,
Náusea/inducido quÃmicamente,
Náusea/tratamiento farmacológico,
Náusea/epidemiologÃa,
Neoplasias/tratamiento farmacológico,
Estudios Prospectivos,
Factores de Riesgo,
Vómitos/inducido quÃmicamente,
Vómitos/tratamiento farmacológico,
Vómitos/epidemiologÃa
OBJECTIVES: The objectives of this study were to determine the sensitivity of ovarian cancer (OC) cell lines (TOV-21G and SKOV-3) to cisplatin and to the recombinant human TRAIL (rhTRAIL), and to evaluate the expression profile of TNFRSF10B, TNFRSF10C, TP53TG5, MDM2, BAX, BCL-2 and CASPASE-8 genes and th...
Background: Cancer is the second most common fatal disease in the world, behind cardiovascular disorders in the first place. It accounts for around 0.3 million deaths per year in India due to the lack of proper diagnostic facilities, prevention and treatment. Current therapeutic methods do not provide ad...
Sensory neuropathy is a dose-limiting side effect of oxaliplatin-based cancer treatment. This study investigated the antinociceptive effect of amifostine and its potential neuroprotective mechanisms on the oxaliplatin-related peripheral sensory neuropathy in mice. Oxaliplatin (1 mg/kg) was injected intra...
The Asiatic pit vipers from the Trimeresurus complex are medically important venomous snakes. These pit vipers are often associated with snakebite that leads to fatal coagulopathy and tissue necrosis. The cytotoxic venoms of Trimeresurus spp.; however, hold great potential for the development of peptide-...