Abstract Specific proteases capable of degrading native triple helical or denatured collagen have been required for many years and have a large spectrum of applications. There are few complete reports that fully uncover production, characterization and purification of fungi collagenases. In this review, ...
Colágeno/metabolismo,
Colagenasas/metabolismo,
Hongos/metabolismo,
Colágeno/química,
Colagenasas/biosíntesis,
Colagenasas/química,
Colagenasas/aislamiento & purificación,
Medios de Cultivo,
Activación Enzimática,
Hongos/clasificación,
Proteolisis,
Especificidad por Sustrato
Nicodemo, Mariana de Castro;
Neves, Lia Renó das;
Aguiar, Josafá Carvalho;
Brito, Flaviane de Souza;
Ferreira, Isabelle;
Sant'Anna, Luciana Barros;
Raniero, Leandro José;
Martins, Rodrigo Álvaro Lopes;
Barja, Paulo Roxo;
Arisawa, Emilia Angela Lo Schiavo.
Abstract Purpose: To evaluate the effect of human amniotic membrane (hAM) fragment on inflammatory response, proliferation of fibroblast and organization of collagen fibers in injured tendon. Methods: Sixty rats were divided into 3 groups: C - surgical procedures without tendon lesion and with simula...
Tendón Calcáneo/lesiones,
Amnios/trasplante,
Traumatismos de los Tendones/cirugía,
Cicatrización de Heridas,
Tendón Calcáneo/patología,
Colágeno/fisiología,
Modelos Animales,
Ratas Wistar,
Rotura/patología,
Rotura/cirugía,
Espectroscopía Infrarroja por Transformada de Fourier,
Traumatismos de los Tendones/patología,
Factores de Tiempo
Abstract Purpose: To compare the polypropylene mesh (Marlex®) to Vicryl®, Parietex composite® and Ultrapro® meshes to assess the occurrence of adhesions in the intraperitoneal implantation. Methods: Sixty Wistar rats were allocated into three groups: PP+V, in which all the animals received a poly...
Colágeno,
Hernia Ventral/cirugía,
Poliésteres,
Poliglactina 910,
Polipropilenos,
Mallas Quirúrgicas,
Adherencias Tisulares/prevención & control,
Pared Abdominal/cirugía,
Materiales Biocompatibles,
Modelos Animales,
Prótesis e Implantes,
Distribución Aleatoria,
Ratas Wistar
Gomes, Mariana Teixeira;
Campos, Gabriela Russo Soeiro;
Piccolo, Natália;
França, Cristiane Miranda;
Guedes, Guelton Hirano;
Lopes, Fabio;
Belotto, Renata A;
Pavani, Christiane;
Lima, Rafael do Nascimento de;
Silva, Daniela de Fátima Teixeira da.
Summary Objective: To analyze morphological characteristics and organization of the collagen fibers of third degree burns from scalding compared to laser therapy and silver sulfadiazine, the latter considered as the gold standard. Method: Were selected 12 animals (Rattus norvegicus) also divided into t...
Liver fibrosis is the most common outcome of chronic liver diseases, and its progression to cirrhosis can only be effectively treated with liver transplantation. The amniotic membrane (AM) has been studied as an alternative therapy for fibrosis diseases mainly for its favorable properties, including anti...
Cardiac remodeling is defined as changes in shape and function of the heart in response to aggression (pressure overload). The sarcoplasmic reticulum calcium ATPase cardiac isoform 2a (SERCA2a) is a known factor that influences function. A wide spectrum of studies report a decrease in SERCA2a in heart fa...
Estenosis Aórtica Supravalvular/complicaciones,
Estenosis Aórtica Supravalvular/metabolismo,
Proteínas de Unión al Calcio/análisis,
Colágeno/análisis,
Diástole/fisiología,
Modelos Animales de Enfermedad,
Ecocardiografía,
Ventrículos Cardíacos/patología,
Ventrículos Cardíacos/fisiopatología,
Hipertrofia Ventricular Izquierda/etiología,
Hipertrofia Ventricular Izquierda/metabolismo,
Hipertrofia Ventricular Izquierda/fisiopatología,
Hipoxia/metabolismo,
Hipoxia/fisiopatología,
Indoles,
Contracción Miocárdica/fisiología,
Ratas Wistar,
ATPasas Transportadoras de Calcio del Retículo Sarcoplásmico/análisis,
ATPasas Transportadoras de Calcio del Retículo Sarcoplásmico/metabolismo,
ATPasas Transportadoras de Calcio del Retículo Sarcoplásmico/fisiología,
Factores de Tiempo,
Disfunción Ventricular Izquierda/etiología,
Disfunción Ventricular Izquierda/metabolismo,
Disfunción Ventricular Izquierda/fisiopatología,
Remodelación Ventricular/fisiología
ABSTRACT The chronological skin aging is a progressive and natural process with genetic and physiological changes. However, ultraviolet (UV) radiation may accelerate the oxidative stress, generating carcinogenesis and photoaging. Natural compounds and their applications are considered a trend in the cosm...
Abstract Introduction: Low intensity laser therapy has proven effective in treating different tissues, reducing inflammation, preventing the formation of fibrous tissue, and promoting muscle regeneration. Objective: To evaluate the effect of low intensity laser therapy, seven days after the injury, and...
Abstract Peripheral ossifying fibroma (POF) is a reactive lesion of oral tissues, associated with local factors such as trauma or presence of dental biofilm. POF treatment consists of curettage of the lesion combined with root scaling of adjacent teeth and/or removal of other sources of irritants. This s...
Antígenos de Superficie/análisis,
Antígenos de Superficie/fisiología,
Neoplasias Óseas/patología,
Diferenciación Celular,
Colágeno/análisis,
Fibroma Osificante/patología,
Encía/patología,
Inmunohistoquímica,
Microscopía de Polarización,
Persona de Mediana Edad,
Osteoblastos/patología,
Factor de Transcripción Sp7,
Factores de Transcripción/análisis,
Factores de Transcripción/fisiología
Abstract The aim of the present study was to evaluate the possible use of a commercial absorbed collagen sponge and bone morphogenetic protein (BMP) for the prevention of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in rats. Twenty rats received intraperitoneal injections of 0.1-mg/kg of zoled...
Osteonecrosis de los Maxilares Asociada a Difosfonatos/prevención & control,
Proteína Morfogenética Ósea 2/administración & dosificación,
Colágeno/administración & dosificación,
Difosfonatos/farmacología,
Imidazoles/farmacología,
Ratas Sprague-Dawley,
Proteínas Recombinantes/administración & dosificación,
Tapones Quirúrgicos de Gaza,
Alveolo Dental/efectos de los fármacos,
Factor de Crecimiento Transformador beta/administración & dosificación,
Cicatrización de Heridas/efectos de los fármacos,
Microtomografía por Rayos X,
Ácido Zoledrónico
