Results: 424

Mutation screening of the sodium iodide symporter gene in a cohort of 105 China patients with congenital hypothyroidism

Objective Dyshormonogenetic congenital hypothyroidism (CH) was reported to be associated with a mutation in the sodium iodide symporter (NIS) gene. The present study was undertaken in the Guangxi Zhuang Autonomous Region of China, to determine the nature and frequency of NIS gene mutations among patients...
ADN

High genetic diversity and small genetic variation among populations of Magnolia wufengensis (Magnoliaceae), revealed by ISSR and SRAP marker

Electron. j. biotechnol; 17 (6), 2014
Background Genetic diversity and genetic variation of 10 populations and subpopulations of Magnolia wufengensis, a new and endangered endemic species, were examined by inter simple sequence repeat (ISSR) and sequence-related amplified polymorphism (SRAP) molecular markers. Compared with other endangered ...

Valor prognóstico dos níveis de DNA circulante em pacientes graves e em pacientes com trauma

Nos últimos anos, o número de estudos que investigam os ácidos nucleicos circulantes como potenciais biomarcadores tem aumentado. A detecção desses biomarcadores é uma alternativa minimamente invasiva para o diagnóstico e o prognóstico de diversas condições clínicas. O valor dos níveis de DNA...
ADN

Analysis of genetic diversity and differentiation of sheep populations in Jordan

Electron. j. biotechnol; 17 (4), 2014
Background Genetic diversity of sheep in Jordan was investigated using microsatellite markers (MS). Six ovine and bovine MS located on chromosomes 2 and 6 of sheep genome were genotyped on 294 individual from ten geographical regions. Results The number of alleles per locus (A), the expected heterozygosi...

The use of a DNA stabilizer in human dental tissues stored under different temperature conditions and time intervals

J. appl. oral sci; 22 (4), 2014
Objective: The present study evaluated the use of a reagent to stabilize the DNA extracted from human dental tissues stored under different temperature conditions and time intervals. Material and Methods: A total of 161 teeth were divided into two distinct groups: intact teeth and isolated dental pulp ti...
ADN

Correlación entre la concentración urinaria de malondialdehído y daño en el ADN de personas expuestas a mercurio

Iatreia; 27 (2), 2014
Objetivo: determinar si la magnitud del daño en el ADN se correlaciona con la concentración de malondialdehído (MDA) urinario en individuos expuestos ocupacionalmente a mercurio y en controles no expuestos. Metodología: se evaluaron 64 historias clínicas (32 de expuestos y 32 de controles) en los qu...

Trampas extracelulares de ADN de eosinófilos en alergias

Iatreia; 27 (2), 2014
La alergia es una reacción de hipersensibilidad iniciada por mecanismos inmunológicos y mediada por anticuerpos o células; se desencadena en individuos previamente sensibilizados a un alérgeno. En la mayoría de los casos, el anticuerpo responsable de la reacción alérgica es la inmunoglobulina E (I...