Caires, A;
Fernandes, G S;
Leme, A M;
Castino, B;
Pessoa, E A;
Fernandes, S M;
Fonseca, C D;
Vattimo, M F;
Schor, N;
Borges, F T.
Cyclosporin-A (CsA) is an immunosuppressant associated with acute kidney injury and chronic kidney disease. Nephrotoxicity associated with CsA involves the increase in afferent and efferent arteriole resistance, decreased renal blood flow (RBF) and glomerular filtration. The aim of this study was to eval...
Lesión Renal Aguda/inducido químicamente,
Lesión Renal Aguda/fisiopatología,
Lesión Renal Aguda/prevención & control,
Bosentán,
Creatinina/sangre,
Ciclosporina/toxicidad,
Antagonistas de los Receptores de Endotelina/farmacología,
Antagonistas de los Receptores de Endotelina/uso terapéutico,
Hemodinámica,
Immunoblotting,
Inmunohistoquímica,
Inmunosupresores/toxicidad,
Riñón/efectos de los fármacos,
Pirimidinas/farmacología,
Ratas Wistar,
Reproducibilidad de los Resultados,
Urea/sangre
The pathophysiological mechanisms associated with the effects of red blood cell (RBC) transfusion on cardiopulmonary function and inflammation are unclear. We developed an experimental model of homologous 14-days stored RBC transfusion in hypovolemic swine to evaluate the short-term effects of transfusio...
Conservación de la Sangre/efectos adversos,
Conservación de la Sangre/métodos,
Fenómenos Fisiológicos Cardiovasculares,
Citocinas/sangre,
Modelos Animales de Enfermedad,
Ensayo de Inmunoadsorción Enzimática,
Transfusión de Eritrocitos/efectos adversos,
Transfusión de Eritrocitos/métodos,
Hemodinámica,
Hipovolemia/terapia,
Neumonía/fisiopatología,
Fenómenos Fisiológicos Respiratorios,
Porcinos,
Resultado del Tratamiento
ABSTRACT Objective: To examine the incidence of hemorrhagic complications in patients undergoing radial cardiac catheterization and using a hemostatic device for arterial compression. Method: A prospective cohort study conducted with patients undergoing elective cardiac catheterization in two hemodyn...
It has been previously demonstrated that the hemodynamic effect induced by angiotensin II (AII) in the liver was completely abolished by losartan while glucose release was partially affected by losartan. Angiotensin II type 1 (AT1) and adrenergic (∝1- and β-) receptors (AR) belong to the G-pro...
Glucosa/metabolismo,
Hipertensión Portal/metabolismo,
Hígado/metabolismo,
Receptor de Angiotensina Tipo 1/fisiología,
Receptores Adrenérgicos alfa/fisiología,
Receptores Adrenérgicos beta/fisiología,
Antagonistas Adrenérgicos beta/farmacología,
Bloqueadores del Receptor Tipo 1 de Angiotensina II/farmacología,
Antagonistas de Receptores de Angiotensina/farmacología,
Hemodinámica/efectos de los fármacos,
Hemodinámica/fisiología,
Hígado/efectos de los fármacos,
Losartán/farmacología,
Prazosina/farmacología,
Propranolol/farmacología,
Ratas Wistar,
Receptor de Angiotensina Tipo 1/efectos de los fármacos,
Receptores Adrenérgicos alfa/efectos de los fármacos,
Receptores Adrenérgicos beta/efectos de los fármacos,
Factores de Tiempo
ABSTRACT Objective: to demonstrate hemodynamic changes during laparoscopic cholecystectomy in elderly patients with trans-esophageal echocardiography. Methods: we studied 31 elderly patients (aged 60 years or older), ASA I or II, who underwent elective laparoscopic cholecystectomy under general, standa...
The conventional analysis and approach to the physiology of the fluid responsiveness has traditionally been focused mainly on the physiology of heart-lung interactions, and on reviews of the technical, methodological, and epidemiological aspects of the dynamic parameters, which are translated into simple...
ABSTRACT Objective: To construct a Standard Operating Procedure (SOP) about the water balance, to be used by the health team in the care of children hospitalized in a pediatric nephrology unit. Method: The study was carried out in two stages: integrative review of the literature for the development of ...
O objetivo deste estudo trás apresentação de conhecimentos com intuito de auxiliar na prevenção de complicações relacionado com a doença renal crônica. Trata-se de uma pesquisa qualitativa e transversal realizada nos Postos de Saúde e Unidades Básicas de Saúde de Valparaíso de Goiás no per...
Objetivo: Investigar os efeitos da administração da corticoterapia antenatal sobre a hemodinâmica fetal, utilizando uma análise longitudinal e quantitativa das curvas de velocidade de fluxo do Doppler das artérias umbilical e cerebral média. Metodologia: Este estudo utilizou revisão de prontuário...
