Antecedentes: al menos el 50% de los casos de aborto espontáneo recurrente son etiológicamente
idiopáticos. Recientemente se han propuesto varios polimorfismos genéticos como factores de
riesgo de susceptibilidad a la pérdida del embarazo. Objetivo: El objetivo del presente estudio
de casos y contro...
BACKGROUND: Persimmon (Diospyros kaki Thunb.) is the most widely cultivated species of the genus Diospyros. In this study, genetic diversity and variations in persimmon genotypes were investigated using single nucleotide polymorphism (SNP) markers identified by genotyping-by-sequencing (GBS) analysis. RE...
At present, there is a concern about the quality of milk and diseases related to its consumption, as it can generate discomfort and allergic reactions in some individuals due to its protein components. Thus, the present study was developed to identify the allele and ...
ABSTRACT Objective To determine the frequency of Human leukocyte antigen alleles and to verify the association of the presence of these alleles with symptoms and other diseases related to celiac disease in patients with autoimmune thyroid diseases. Methods A questionnaire on the symptoms and diseases a...
We aimed to present an overview of the literature regarding the interaction between physical exercise and APOE gene polymorphism on cognitive function, particularly in patients with Alzheimer's disease (AD). Firstly, this review focused on the effect of the physical exercise on cognitive function, regard...
Abstract INTRODUCTION: Tuberculosis (TB) is the leading cause of death worldwide caused by a single infectious disease agent. Brazil, Russia, India, China, and South Africa (BRICS) account for more than half of the world's TB cases. Bacillus Calmette-Guérin (BCG) remains the only vaccine available des...
Ruiz, Álvaro J;
Patiño, Luisa Fernanda;
Amaya, Kelly;
Gómez, Juan Esteban;
Ordóñez, Felipe;
Paternina, Samuel;
Mercado, Misael;
Pachajoa, Harry;
Campo, Rafael;
Giraldo, Gustavo;
Jiménez, Ravagly;
Zuluaga, Nohora;
Monroy, Jeniffer;
Gil-Forero, Julián;
Matallana, Audrey;
Rivera, Carolina;
Coll, Mauricio;
Peña, William;
Manjarrez, Octavio;
Toro, Juan Martín;
Barrera, Álvaro;
Hoyos, Diego;
García, Harold.
Resumen Introducción: La hipercolesterolemia familiar homocigótica (HFHo) se caracteriza por niveles muy elevados de cLDL y por enfermedad aterosclerótica temprana. Aunque la frecuencia es baja (1/300.000), las complicaciones son muy severas y pueden ser evitadas. Encontrar y tratar esta población ...
BACKGROUND: Meretrix petechialis is one of the commercially important marine bivalves. In this study, we selected six highly polymorphic EST-derived microsatellite markers to assess the genetic diversity and population differentiation on nine wild populations of Meretrix petechialis. RESULTS: The number ...
ABSTRACT Background: We evaluated different technological approaches and anti-D clones to propose the most appropriate serologic strategy in detecting the largest numbers of D variants in blood donors. Methods: We selected 101 samples from Brazilian blood donors with different expressions of D in our d...
Costa-Riquetto, Aline D.;
Santana, Lucas S.;
Caetano, Lílian A.;
Lerário, Antônio M.;
Correia-Deur, Joya E. M.;
Bertola, Débora R.;
Kim, Chong A.;
Nery, Márcia;
Jorge, Alexander A. L.;
Teles, Milena G..
ABSTRACT Objective: Our aim is to establish genetic diagnosis of congenital generalized lipodystrophy (CGL) using targeted massively parallel sequencing (MPS), also known as next-generation sequencing (NGS). Subjects and methods: Nine unrelated individuals with a clinical diagnosis of CGL were recruite...
