Results: 71

Can natural killer cell activity help screen patients requiring a biopsy for the diagnosis of prostate cancer?

Int. braz. j. urol; 46 (2), 2020
ABSTRACT Purpose To evaluate the usefulness of natural killer cell activity (NKA) in diagnosing prostate cancer (PC). Materials and Methods The medical records of patients who underwent transrectal prostate biopsy (TRBx) at Korea University Ansan Hospital between May 2017 and December 2017 were retro...

Salivary biomarkers in Alzheimer´s disease

Int. j. morphol; 38 (1), 2020
The hypotheses currently considered the most likely causes of Alzheimer's disease (AD) are amyloid beta peptide deposition in the cerebral cortex and hyperphosphorylation of the Tau protein, with the consequent formation of neurofibrillary tangles. In clinical practice, although not accurate, AD diagnosi...

Susceptibility of the elderly to SARS-COV-2 infection: ace-2 overexpression, shedding, and antibody-dependent enhancement (ADE)

Clinics; 75 (), 2020
The world is currently facing a serious SARS-CoV-2 infection pandemic. </mac_aq>This virus is a new isolate of coronavirus, and the current infection crisis has surpassed the SARS and MERS epidemics</mac_aq> that occurred in 2002 and 2013, respectively. SARS-CoV-2 has currently infected more ...

Preconditioning with L-Ala-Gln reduces the expression of inflammatory markers (TNF-α, NF-κB, IL-6 and HO-1) in an injury animal model of cerebrovascular ischemia in Meriones unguiculatus (gerbils)

Acta cir. bras; 35 (6), 2020
Abstract Purpose To evaluate the neuroprotective effect of L-alanyl-glutamine in a gerbil model of brain ischemia-reperfusion injury based on immunohistochemical quantification of pro-inflammatory and cell activation biomarkers (TNF-α, NF-κB, IL-6 and HO-1). Methods Male gerbils weighing 10...

Modelo metabonômico para avaliação da regressão do diabetes mellitus tipo 2 após cirurgia bariátrica

Rev. Col. Bras. Cir; 47 (), 2020
RESUMO Objetivo: avaliar as diferenças no perfil metabonômico de pacientes que atingiram remissão de diabetes mellitus tipo 2 (DM2) após cirurgia bariátrica em relação aos que apresentaram manutenção ou recidiva dessa condição após a cirurgia. Métodos: Participaram do estudo 33 pacientes o...

Smoking history: relationships with inflammatory markers, metabolic markers, body composition, muscle strength, and cardiopulmonary capacity in current smokers

J. bras. pneumol; 46 (5), 2020
ABSTRACT Objective: To determine the relationships that smoking history has with inflammatory markers, metabolic markers, body composition, muscle strength, and cardiopulmonary capacity in current smokers. Methods: This was a cross-sectional study involving 65 smokers (age range: 18-60 years). On three...

Un enfoque actual para el diagnóstico precoz y tratamiento de la insuficiencia renal aguda

Medwave; 20 (5), 2020
La insuficiencia renal aguda es el síndrome caracterizado por una disminución brusca, sostenida y potencialmente reversible de la velocidad de filtración glomerular y de las funciones tubulares, afectando de forma global la función renal. Comprende una serie de eventos que se inician con la presencia...

miR-22 and cerebral microbleeds in brainstem and deep area are associated with depression one month after ischemic stroke

Braz. j. med. biol. res; 53 (5), 2020
In this study, we aimed to explore the relationship among miR-22, deep cerebral microbleeds (CMBs), and post-stroke depression (PSD) 1 month after ischemic stroke. We consecutively recruited 257 patients with first-ever and recurrent acute cerebral infarction and performed PSD diagnosis in accordance wit...

Physical activity impact on motor development and oxidative stress biomarkers in school children with intellectual disability

SUMMARY OBJECTIVE Lower physical fitness and poor motor performance were shown to be linked with higher levels of oxidative stress in children and adolescents with intellectual disabilities. Therefore, a moderate aerobic exercise for 12-weeks was performed to evaluate the effects of physical activity s...

Oxidative stress, telomere length, and frailty in an old age population

Rev. invest. clín; 71 (6), 2019
Abstract Background A global aging population requires focusing on the risk factors for unhealthy aging, preventive medicine, and chronic disease management. The identification of adverse health outcomes in older adults has been addressed by the characterization of frailty as a biological syndrome. In t...