Results: 17

Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats

Acta cir. bras; 32 (3), 2017
Abstract Purpose: To investigate the effects of cyclosporine A on renal ischemia-reperfusion injury during transient hyperglycemia in rats. Methods: In a model of ischemia-reperfusion-induced renal injury and transiently induced hyperglycemia by intraperitoneal injection of glucose, 2.5 g.kg-1, Wistar...

Ischemic postconditioning assessment in the liver of rats undergoing mesenteric ischemia and reperfusion

Abstract Introduction: Ischemic postconditioning is a method that shows evidence of efficacy in minimizing reperfusion injury; however, its effectiveness in preventing injuries in distant organs is still unknown, especially in those who have undergone mesenteric ischemia and reperfusion. Objective: To ...

Toll-like receptor 7 involves the injury in acute kidney ischemia/reperfusion of STZ-induced diabetic rats

Acta cir. bras; 31 (7), 2016
ABSTRACT PURPOSE: To determine whether Toll-like receptor 7 (TLR7) is the potential targets of prevention or progression in the renal ischemia/reperfusion (I/R) injury of STZ-induced diabetic rats. METHODS: Thirty six Sprague-Dawley rats were randomly arranged to the nondiabetic (ND) or diabetic group ...

The protective cardiac effects of Β-myrcene after global cerebral ischemia/reperfusion in C57BL/J6 mouse

Acta cir. bras; 31 (7), 2016
ABSTRACT PURPOSE: To investigate the protective effect of β-myrcene (MYR) on oxidative and histological damage in mice heart tissue caused global cerebral ischemia/reperfusion (IR) in C57BL/J6 mice. METHODS: Animals(n=40) were randomly divided into four groups: (1)control, (2)IR, (3)MYR and (4)MYR...

Effect of Otostegia persica extract on ischemia/reperfusion induced renal damage in diabetic rats. A biochemical study

Acta cir. bras; 31 (6), 2016
ABSTRACT PURPOSE: To evaluate the effect of Otostegia persica (O. persica) extract on renal damage induced by ischemia/reperfusion (I/R) in diabetic rats. METHODS: Forty-eight rats were subjected to right nephrectomy; then, they were allocated into six groups: Sham; Diabetic sham; I/R; Diabetic I/R; I/...

Impacto de la ciclosporina en el daño renal por isquemia reperfusión
Impact of the ciclosporine in the renal failure for ischemia reperfusion

Rev. chil. urol; 62 (1), 1997
El éxito de la ciclosporina A (CsA) como inmunosupresor se ha visto limitado por su nefrotoxicidad. Estudiamos el efecto de la CsA sobre el daño renal isquémico. Ratas Sprague-Dowley monorrenas fueron sometidas a 60 minutos de clampeo de la arteria renal derecha. La mortalidad por insuficiencia renal ...

El efecto de un inhibidor de la xantinoxidasa asociado a la inhibición reversible de la monoaminoxidasa en el daño renal por isquemia reperfusión
The effect of a xanthine oxidase inhibitor associated to the reversible inhibition of monoamine oxidase in renal failure by ischemic-reperfusion

Rev. chil. urol; 60 (2), 1995
Diversas sustancias han mostrado efectividad en la protección del daño renal por isquemia-reperfusión. La inhibición de la xantínoxidasa (XO) por alopurinol (ALO) ha sido una de las más estudiadas. Previamente, mostramos el efecto protector de la Moclobemida (MOC), un inhibidor reversible de la mon...