Abstract Background: Dexmedetomidine (DEX) is an α2-adrenergic receptor agonist used for its sedative, analgesic, and anxiolytic effects. Non-Operating Room Anesthesia (NORA) is a modality of anesthesia that can be done under general anesthesia or procedural sedation or/and analgesia. In this parti...
Abstract Objective: This meta-analysis aimed to compare the efficacy and safety of dexmedetomidine and Clonidine as an adjuvant to local anesthetics in BPBs. Methods: Two investigators independently searched databases to identify all RCTs comparing the efficacy and/or safety of dexmedetomidine and Clon...
The present study aimed at assessing the effects of combining 20 mg/kg S(+) ketamine with 25 μg/kg dexmedetomidine and 0.4 mg/kg butorphanol on the physiological parameters and anesthetic recovery time and score of eight captive scarlet macaw (Ara macao) specimens. These specimens were captured at the M...
INTRODUCTION: Acute kidney injury (AKI) is a frequent complication after transcatheter aortic valve implantation (TAVI), and it presents a higher risk of myocardial infarction, severe bleeding, transfusión, dialysis, and mortality. Dexmedetomidine has a protective effect on AKI after adult cardiac surge...
Dexmedetomidina/administración & dosificación,
Hipnóticos y Sedantes/administración & dosificación,
Lesión Renal Aguda/prevención & control,
Lesión Renal Aguda/epidemiología,
Reemplazo de la Válvula Aórtica Transcatéter/métodos,
Sedación Consciente,
Estudios Retrospectivos,
Reemplazo de la Válvula Aórtica Transcatéter/efectos adversos,
Creatinina/sangre,
Creatinina/orina,
Tiempo de Internación
OBJECTIVES: To Synthesize the most used adjuvants in spinal anesthesia, summarize the mechanisms of action, indication, dose, adverse events, and safety outcomes described. METHODOLOGY: Non-systematic review in the medline, embase, central and Scielo databases without time or language limits, focused on ...
BACKGROUND: Arthroscopic knee surgery refers to different surgical interventions in the knee joint and many studies investigated postoperative pain control, Adductor canal block (ACB) as a new alternative technique to femoral nerve block (FNB) provides post-operative pain control with a multimodal analge...
Reconstrucción del Ligamento Cruzado Anterior/métodos,
Bloqueo Nervioso/métodos,
Dexametasona/administración & dosificación,
Sulfato de Magnesio/administración & dosificación,
Dexmedetomidina/administración & dosificación,
Bupivacaína/administración & dosificación,
Método Doble Ciego,
Dolor Postoperatorio,
Dimensión del Dolor,
Analgesia/métodos,
Estudios Prospectivos,
Ultrasonografía Intervencional,
Artroscopía
BACKGROUND: Stable hemodynamics in hip arthroscopy is one of the most important tasks. Recently, dexmedetomidine has been considered a safe analgesic and sedative adjuvant in different surgeries. Ultrasound-guided fascia iliaca compartment block (FICB) is a technique used to produce postoperative analges...
Artroscopía/métodos,
Dexmedetomidina/administración & dosificación,
Infusiones Intravenosas,
Estudios Prospectivos,
Bloqueo Nervioso/métodos,
Cadera/cirugía,
Método Doble Ciego,
Ilion/efectos de los fármacos,
Íleon/inervación,
Frecuencia Cardíaca,
Monitoreo Intraoperatorio,
Dolor Postoperatorio,
Dimensión del Dolor,
Bupivacaína/administración & dosificación,
Hemodinámica
INTRODUCTION: Given the scenarios of care in critical patients in the emergency room, the administration of medications is required quickly, especially in patients with mental disturbance or shock. Intranasal drug administration has been shown to be a viable alternative for the management of critically i...
Analgésicos/administración & dosificación,
Hipnóticos y Sedantes/administración & dosificación,
Administración Intranasal,
Depuración Mucociliar,
Disponibilidad Biológica,
Urgencias Médicas,
Analgésicos/farmacocinética,
Hipnóticos y Sedantes/farmacocinética,
Enfermedad Crítica,
Anestésicos,
Dexmedetomidina,
Ketamina,
Midazolam,
Fentanilo,
Flumazenil,
Naloxona,
Haloperidol
Abstract Background Dexmedetomidine (Dex) is widely used, and its most common side effect is bradycardia. The complete mechanism through which Dex induces bradycardia has not been elucidated. This research investigates the expression of gap junction proteins Connexin30.2 (Cx30.2) and Connexin40 (Cx40) w...
Abstract Mutations in SCN8A gene lead to changes in sodium channels in the brain, which are correlated with severe epileptic syndrome. Due to the rarity, there are few studies that support anesthesia in that population. The present study aims to report alternatives to inhalation anesthesia at epileptic e...
