Hortia oreadica
is indiscriminated used by people from Cerrado. However, vegetable raw
material quality is decisive in obtaining inter
mediate and final products. So, this study aimed to establish
quality parameters of
H. oreadica
. For this, we performed the phytochemical screeni...
SUMMARY: Cisplatin (Cis) is an important chemotherapeutic agent used in cancer treatment. Males exposed to Cis were reported to exhibit testicular toxicity. Cis-induced testicular toxicity is mediated by oxidative stress, inflammation, testosterone inhibition and apoptosis. Accordingly, this study was co...
Camellia sinensis/química,
Extractos Vegetales/farmacología,
Té/química,
Infliximab/farmacología,
Cisplatino/toxicidad,
Testículo/efectos de los fármacos,
Recuento de Espermatozoides,
Factor de Necrosis Tumoral alfa/antagonistas & inhibidores,
Apoptosis,
Estrés Oxidativo,
Inflamación,
Ratas Sprague-Dawley,
Extractos Vegetales/química,
Inmunohistoquímica,
Malondialdehído/análisis,
Glutatión/análisis,
Testículo/patología
SUMMARY: Mormodica balsamina is a valuable medicinal plant that is used to treat wounds and inflammation; its leaves are also used as an antibiotic and in the treatment of stomach pain. This study was conducted to determine the anti-ulcer activity of methanolic leaf extract of Mormodica balsamina on etha...
Momordica/química,
Momordica balsamica,
Extractos Vegetales/administración & dosificación,
Hojas de la Planta,
Etanol/toxicidad,
Úlcera Gástrica/tratamiento farmacológico,
Mucosa Gástrica/efectos de los fármacos,
Plantas Medicinales,
Úlcera Gástrica/inducido químicamente,
Extractos Vegetales/química,
Antiulcerosos/administración & dosificación,
Antiulcerosos/química,
Modelos Animales de Enfermedad
The purpose of this work was to evaluate the antioxidant capacity of Prosopis pallida (Fabaceae) fruits “algarrobo”, in addition to determine their main chemical components. Fruit purified extracts from the regions of Tumbes, Piura, Lambayeque, and La Libertad (Peru) were eval...
dos Santos, Jymmys Lopes;
Silva, Ana Mara de Oliveira e;
Souza, Lúcio Marques Vieira;
Pereira, Raquel Oliveira;
Lima, Clésio Andrade;
Abreu, Lucas Silva;
Montalvao, Monalisa Martins;
Correa, Cristiane Bani;
Rabelo, Thallita Kelly;
Duarte, Marcelo Cavalcante;
Aidar, Felipe Jose;
Tavares, Josean Fechine;
Estevam, Charles dos Santos;
Marçal, Anderson Carlos.
In order to understand antidiabetic potential and toxicity, this study aimed to evaluate the acute toxicity and antidiabetic activity of ethanolic extract and ethyl acetate fraction obtained from Coutoubea spicata “nicolau” shoots. Chemical constituents and acute toxicity were investigated. In alloxa...
The neuroprotective effect of flower and fruit parts of Capparis ovata Desf. var. palaestina Zoh. plant was investigated in H2O2-induced cytotoxicity in SH-SY5Y cells. The cells were treated with H2O2 alone or pretreated with flower (COMFL) and fruit extract (COMFR) of C. ovatavar. palaesti...
Amaral, Eduarda Carolina;
da Silva, Gustavo Ratti;
Braga, Fernanda de Abreu;
Palozi, Rhanany Alan Calloi;
Lorençone, Bethânia Rosa;
Marques, Aline Aparecida Macedo;
Moreno, Karyne Garcia Tafarelo;
Leite, Patrícia Regina Terço;
Barboza, Lorena Neris;
Souza, Roosevelt Isaias Carvalho;
dos Santos, Ariany Carvalho;
Lovato, Evellyn Claudia Wietzikoski;
Ribeiro-Paes, João Tadeu;
Junior, Arquimedes Gasparotto;
Lívero, Francislaine Aparecida dos Reis.
This study proposes an unpreceded model of cardiovascular disease by combining alcohol and energy drink intake with hookah smoking to investigate the cardiovascular effects of Baccharis trimera (Less.) DC., a medicinal plant used to treat dyslipidemia. For 10 weeks, Wistar rats (n=8) re...
The objective of this work was to evaluate the gastroprotective activity of the crude ethanolic extract (CEE) from the stem barks of Piptadenia viridiflora using the acute models of inducing gastric ulcers by ethanol, ethanol-acidified, and ischemia-reperfusion, and correlating thi...
Grewia tenax (Forssk.) Fiori (Malvaceae) grows in the Arabian Peninsula and is used for several medicinal purposes. To characterize the dermatological bioactivities of G. tenax in terms of its antimelanoma, antityrosinase and antioxidant activities. Cytotoxicity was assesse...
Grewia/química,
Melanoma/tratamiento farmacológico,
Antioxidantes/farmacología,
Neoplasias Cutáneas/tratamiento farmacológico,
Arabia Saudita,
Técnicas In Vitro,
Extractos Vegetales/farmacología,
Línea Celular Tumoral/efectos de los fármacos,
Monofenol Monooxigenasa/antagonistas & inhibidores,
Hojas de la Planta,
Especies Reactivas de Oxígeno,
Lupanos/análisis,
Sitoesteroles/análisis,
Antioxidantes/química,
Extractos Vegetales/química,
Cromatografía Líquida de Alta Presión
Núñez, Marvin J;
Paz-González, Alma D;
Vásquez-Jiménez, Lenci K;
Castillo, Ulises G;
Moo-Puc, Rosa;
Chan-Bacab, Jesús M;
Aguilera-Arreola, Guadalupe;
Catalán-Gonzalez, Lucero;
Quintana-Gómez, Alexis Uriel;
Castañeda-Sánchez, Jorge Ismael;
Luna-Herrera, Julieta;
Rivera, Gildardo.
Currently, in developing countries, parasitic and bacterial diseases as amebiasis, giardiasis, trichonomiasis, leishmaniasis, trypanosomiasis, tuberculosis, and nocardiasis are a public health problem. The pharmacological treatment for these diseases is not completely effective and c...
Flora,
Extractos Vegetales/farmacología,
Antiparasitarios/farmacología,
Antibacterianos/farmacología,
Parásitos/efectos de los fármacos,
Técnicas In Vitro,
El Salvador,
Bacterias/efectos de los fármacos,
Mycobacterium tuberculosis,
Trypanosoma cruzi/efectos de los fármacos,
Extractos Vegetales/química,
Antiparasitarios/química,
Antibacterianos/química,
Pruebas de Sensibilidad Microbiana,
Flavonoides/análisis,
Monoterpenos/análisis,
Amoeba/efectos de los fármacos,
Cromatografía Líquida de Alta Presión
