Uso da Terapia Diurética em Pacientes com Insuficiência Cardíaca Descompensada e Lesão Renal Aguda. O Que Fazer nesse Dilema?
Arq. bras. cardiol; 116 (4), 2021
Results: 43
Poisoning in domestic cats in Brazil: toxicants, clinical signs, and therapeutic approaches
Arq. bras. med. vet. zootec. (Online); 73 (1), 2021
This study evaluated the most common toxic agents affecting domestic cats, the clinical signs of toxicity, and the therapeutic approaches for recovery. A survey on poisoning in cats was conducted among small animal veterinary practitioners from 2017 to 2018. Of the 748 completed questionnaires, 543 (72.6...
Desenlaces asociados con solución salina normal versus lactato de ringer en sepsis y choque séptico o hipovolémico
Repert. med. cir; 30 (1), 2021
Introducción: los cristaloides son medicamentos usados en pacientes críticamente enfermos, con resultados ambiguos cuando se utilizan soluciones balanceadas versus solución salina normal. Objetivo: conocer si existen diferencias al usar solución salina 0.9% vs. lactato de...
Sepsis/terapia, Choque Séptico/terapia, Solución Salina/uso terapéutico, Choque/terapia, Lactato de Ringer/uso terapéutico, Solución Salina/efectos adversos, Lactato de Ringer/efectos adversos, Sepsis/mortalidad, Choque/mortalidad, Choque Séptico/mortalidad, Lesión Renal Aguda/inducido químicamente, Tiempo de Internación, Análisis Multivariante, Resultado del Tratamiento, Estudios Retrospectivos
The renoprotective effects of Heme Oxygenase-1 during contrast-induced acute kidney injury in preclinical diabetic models
Clinics; 76 (), 2021
OBJECTIVES: Contrast-induced acute kidney injury (CI-AKI) is an important clinical problem that can be aggravated by diabetes mellitus, a major risk factor. However, heme oxygenase-1 (HO-1), a promising therapeutic target, can exert antioxidant effects against CI-AKI. Thus, we investigated the role of HO...
Impacto do uso de drogas nefrotóxicas em pacientes pediátricos graves
Rev. bras. ter. intensiva; 32 (4), 2020
RESUMO Objetivo: Avaliar a associação entre uso de drogas nefrotóxicas e lesão renal aguda em pacientes pediátricos graves. Métodos: Estudo de coorte retrospectivo envolvendo todas as crianças internadas na unidade de terapia intensiva de um hospital pediátrico durante o período de 1 ano. A le...
Quercetin protects against acetaminophen-induced acute nephrotoxicity associated with the inhibition of biomarkers of acute kidney injury in rats
Int. j. morphol; 38 (4), 2020
Acetaminophen (also called paracetamol, or APAP) causes acute kidney injury after accidental or intentional ingestion of a toxic dose of the drug. We tested whether the antioxidant and anti-inflammatory agent, quercetin (QUR) given alone can protect against acute nephrotoxicity induced by APAP overdose i...
Lesión Renal Aguda/inducido químicamente, Acetaminofén/toxicidad, Quercetina/administración & dosificación, Quercetina/farmacología, Modelos Animales de Enfermedad, Biomarcadores/análisis, Estrés Oxidativo/efectos de los fármacos, Riñón/efectos de los fármacos, Sustancias Protectoras, Antioxidantes/administración & dosificación, Antioxidantes/farmacología, Creatinina, Inflamación
Vitamin D Toxicity
J. bras. nefrol; 42 (2), 2020
Abstract Fortification of food products with vitamin D was central to the eradication of rickets in the early parts of the 20th century in the United States. In the subsequent almost 100 years since, accumulating evidence has linked vitamin D deficiency to a variety of outcomes, and this has paralleled g...
Lesión Renal Aguda/inducido químicamente, Lesión Renal Aguda/terapia, Suplementos Dietéticos/provisión & distribución, Suplementos Dietéticos/toxicidad, Hipercalcemia/inducido químicamente, Hipercalcemia/complicaciones, Hipercalcemia/diagnóstico, Hipercalcemia/terapia, Raquitismo/epidemiología, Raquitismo/prevención & control, Resultado del Tratamiento, Vitamina D/toxicidad, Deficiencia de Vitamina D/complicaciones, Deficiencia de Vitamina D/tratamiento farmacológico, Privación de Tratamiento
Ameliorative effect of vitamin E on biochemical and ultrastructural changes in artemether-induced renal toxicity in rats
Int. j. morphol; 38 (2), 2020
This experiment was designed to study the administration of normal doses of one of recent antimalarial drug and coadministration of vitamin E on the kidney tissue. A total twenty-four adult male albino rats were used and divided into four groups: the first one served as a control, the second received art...
Prevalência de nefropatia induzida por contraste em pacientes cardíacos de um setor de hemodinâmica
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online); 12 (), 2020
Objetivo: Determinar a prevalência da nefropatia induzida por contraste em pacientes cardiopatas submetidos a procedimentos angiográficos de diagnóstico e/ou tratamento. Método: Estudo prospectivo, quantitativo, realizado no setor de hemodinâmica de um hospital de grande porte, situado na região no...
Estudios Prospectivos, Enfermedades Renales/inducido químicamente, Cardiopatías/complicaciones, Cardiopatías/diagnóstico por imagen, Angiografía/efectos adversos, Enfermedades Renales/epidemiología, Medios de Contraste/efectos adversos, Lesión Renal Aguda/inducido químicamente, Enfermedad Coronaria/complicaciones, Hemodinámica
Drug-induced nephrotoxicity
Rev. Assoc. Med. Bras. (1992, Impr.); 66 (supl.1), 2020
SUMMARY Acute kidney injury is a very common diagnosis, present in up to 60% of critical patients, and its third main cause is drug toxicity. Nephrotoxicity can be defined as any renal injury caused directly or indirectly by medications, with acute renal failure, tubulopathies, and glomerulopathies as co...