Results: 22

Efficacy of tacrolimus for induction of remission in patients with moderate-to-severe ulcerative colitis: a systematic review and meta-analysis

Arq. gastroenterol; 54 (2), 2017
ABSTRACT BACKGROUND There is evidence that shows that calcineurin inhibitors may be useful for the treatment of severe ulcerative colitis. However, evidence regarding the efficacy of tacrolimus for remission induction in this setting is scarce. OBJECTIVE To develop a systematic review on the existing...

Tacrolimus eye drops as monotherapy for vernal keratoconjunctivitis: a randomized controlled trial

Arq. bras. oftalmol; 80 (3), 2017
ABSTRACT Purpose: To assess the efficacy of monotherapy using tacrolimus eye drops versus sodium cromoglycate for the treatment of vernal keratoconjunctivitis (VKC). Methods: Randomized double-masked controlled trial comparing the efficacy of tacrolimus 0.03% eye drops t.i.d. (Group 1) with sodium crom...

Protocolo clínico e diretrizes terapêuticas da síndrome nefrótica primária em crianças e adolescentes

Remote ischemic preconditioning and tacrolimus in the fetal small bowel transplant in mice

Acta cir. bras; 31 (10), 2016
ABSTRACT PURPOSE: To evaluate the effect of remote ischemic preconditioning (IPC-R) in the fetal small bowel transplantation model. METHODS: Two groups were constituted: The Isogenic transplant (ISO, C57BL/6 mice, n=24) and the allogenic transplant (ALO, BALB/c mice, n=24). In each group, the animals w...

Periorbital discoid lupus: a rare localization in a patient with systemic lupus erythematosus

An. bras. dermatol; 91 (5,supl.1), 2016
Abstract A 40-year-old female patient with a 5-year history of systemic lupus erythematosus was referred to our policlinic with complaints of erythema, atrophy, and telangiectasia on the upper eyelids for 8 months. No associated mucocutaneous lesion was present. Biopsy taken by our ophthalmology departme...

Análisis de impacto presupuestal de everolimus más tacrolimus y prednisolona comparado con tacrolimus y prednisolona para la profilaxis del rechazo en los receptores de trasplante de hígado en Colombia
Analysis of budget impact of everolimus plus tacrolimus and prednisolone compared to tacrolimus and prednisolone for rejection prophylaxis in liver transplant recipients in Colombia

Tecnologías evaluadas: Intervención: e verolimus más tacrolimus y corticoesteroide en pacientes con trasplante de hígado. Comparador: tacrolimus y prednisolona. Población: Adultos receptores trasplante de hígado por primera vez. Perspectiva: Tercer pagador, que en el caso colombiano corresponde al ...

Effectiveness and safety of topical tacrolimus monotherapy for repigmentation in vitiligo: a comprehensive literature review

An. bras. dermatol; 91 (2), 2016
Abstract Thus far, several small studies and case reports on the use of topical immunomodulators in vitiligo have been published. We undertook a comprehensive literature review, searching for studies evaluating clinical response to tacrolimus topical therapy for vitiligo. A search was performed on PubMed...

Uso de imunossupressores (everolimo, sirolimo e tacrolimo) em transplantes pulmonares

Contexto: Os transplantes de pulmão salvaram mais de 378 vidas no SUS. Entretanto, os transplantes estão entre as trinta terapias mais dispendiosas acessíveis universalmente a toda população brasileira, reembolsadas pelo Sistema Único de Saúde do Brasil, SUS, e há crítica auto-limitação de ór...

Allogeneic hematopoietic stem cell transplantation in the elderly: Predicting the risk for non relapse mortality

Medicina (B.Aires); 75 (4), 2015
We have retrospectively reviewed 137 medical records of patients older than 50 years receiving an allogeneic hematopoietic stem cell transplantation (HSCT) between January 1997 and July 2013. Median follow up was 1.3 years. Sex, age, diagnosis, disease stage, comorbidities (according to HCT-CI score), ty...

Efectividad y seguridad de tacrolimus como inmunosupresión primaria en receptores de trasplante renal
Effectiveness and safety of tacrolimus as primary immunosuppression in renal transplant recipients

Antecedentes: Descripción de la condición de salud de interés: Según cifras del Fondo Colombiano de Enfermedades de Alto Costo en su documento sobre la enfermedad renal crónica para del año 2011, en Colombia hay 788.565 personas con Enfermedad Renal Crónica, de este total, el 18,2% corresponden al...