ABSTRACT BACKGROUND: Gastric cancer is the second leading cause of cancer-related death globally. Unfortunately, the survival rate of the gastric cancer patients who underwent chemotherapy following surgery has been less than a half. Besides, chemotherapy has many side effects. Current evidence suggest...
Abstract Purpose: To examine the effects of Arrabidaa chica (Bignoniacea) extract, a native plant of the Amazon known as crajiru, on a 7,12-dimethyl-1,2-benzanthracene (DMBA)-induced breast cancer model in Wistar rats. Methods: We compared the response of breast cancer to the oral administration of A. ...
9,10-Dimetil-1,2-benzantraceno,
Antineoplásicos/farmacología,
Antineoplásicos/uso terapéutico,
Bignoniaceae/química,
Neoplasias de la Mama/diagnóstico por imagen,
Neoplasias de la Mama/tratamiento farmacológico,
Neoplasias de la Mama/patología,
Carcinógenos,
Carcinoma/diagnóstico por imagen,
Carcinoma/tratamiento farmacológico,
Carcinoma/patología,
Catalasa/análisis,
Fluorodesoxiglucosa F18,
Glutatión Peroxidasa/análisis,
Neoplasias Experimentales/tratamiento farmacológico,
Extractos Vegetales/farmacología,
Ratas Wistar,
Vincristina/farmacología,
Resultado del Tratamiento
Objetivo: analisar a utilização de medicamentos prescritos no setor de terapia semi-intensiva da oncopediatria em um hospital filantrópico, tendo em vista o desenvolvimento da farmacovigilância na prática farmacêutica. Métodos: foi realizada avaliação das prescrições médicas e pesquisa biblio...
The objective of this study was to evaluate the hepatoprotective effect of the honey bee Apis mellifera ethanolic extract of the red propolis, obtained in four municipalities of the Rio Grande do Norte semi-arid region, through an in vitro evaluation of the antineoplastic potential in human hepatic carci...
In the present study, we investigated the antiproliferative activity of essential oil from leaves of Melissa officinalis L. grown in Southern Bosnia and Herzegovina. In vitro evaluation of antiproliferative activity of the M. officinalis essential oil was carried out on three human tumor cell lines: MCF-...
Melissa,
Aceites Volátiles/farmacología,
Aceites Volátiles/química,
Proliferación Celular/efectos de los fármacos,
Línea Celular Tumoral/efectos de los fármacos,
Antineoplásicos/farmacología,
Antineoplásicos/química,
Hojas de la Planta,
Técnicas In Vitro,
Cromatografía de Gases y Espectrometría de Masas,
Monoterpenos/análisis,
Sesquiterpenos/análisis,
Células Tumorales Cultivadas
Abstract The study aimed to evaluate the antimicrobial activity, antioxidant, toxicity and phytochemical screening of the Red Propolis Alagoas. Antimicrobial activity was evaluated by disk diffusion method. Determination of antioxidant activity was performed using the DPPH assay (1.1-diphenyl-2-picrylhy...
Abstract Background Febrile neutropenia (FN) is a common complication in children who receive chemotherapy for cancer. Objective The objective of this study was to evaluate the clinical efficacy of the continuous versus intermittent infusion of piperacillin/tazobactam (TZP) in febrile neutropenic pedia...
The purpose of the study was to evaluate the outcome of patients under 18 months diagnosed with neuroblastoma. Between April 2006 and December 2013, 45 consecutive patients followed in Hospital de Pediatría Garrahan, were retrospectively reviewed. With a median age of 9.3 months (1-18 months) N-myc ampl...
Objetivo: identificar o período mais crítico da fadiga durante a quimioterapia com protocolo
doxorrubicina + ciclofosfamida seguido de docetaxel em mulheres com câncer de mama utilizando o pictograma de fadiga. Método: estudo descritivo, prospectivo com abordagem quantitativa. Para um melhor monitora...
Background: Prodigiosin has been demonstrated to be an important candidate in investigating anticancer drugs and in many other applications in recent years. However, industrial production of prodigiosin has not been achieved. In this study, we found a prodigiosin-producing strain, Serratia marcescens FZS...
Serratia marcescens/metabolismo,
Prodigiosina/biosíntesis,
Prodigiosina/farmacología,
Antineoplásicos/farmacología,
Fermentación,
Aceite de Oliva/química,
Arachis/química,
Polvos,
Prodigiosina/aislamiento & purificación,
Cromatografía Líquida de Alta Presión,
Células Tumorales Cultivadas/efectos de los fármacos,
Nitrógeno,
Acetatos,
Cromatografía Liquida,
Espectrometría de Masas,
Técnicas de Cultivo de Célula
