Cut-off values for anti-dsDNA, anti-nucleosome and anti-C1q antibodies tests and for complement-mediated hemolytic activity (CH50) were explored to identify patients with high risk of developing severe lupus nephritis (LN). Forty-one patients with confirmed systemic lupus erythematosus (SLE) were identif...
Anticuerpos Antinucleares/sangre,
Biomarcadores/sangre,
Complemento C1q/inmunología,
Ensayo de Actividad Hemolítica de Complemento/métodos,
Ensayo de Actividad Hemolítica de Complemento/normas,
Pruebas Inmunológicas/métodos,
Pruebas Inmunológicas/normas,
Lupus Eritematoso Sistémico/sangre,
Lupus Eritematoso Sistémico/inmunología,
Nefritis Lúpica/sangre,
Nefritis Lúpica/diagnóstico,
Nucleosomas/inmunología,
Estándares de Referencia,
Estudios Retrospectivos,
Medición de Riesgo/métodos,
Factores de Riesgo,
Sensibilidad y Especificidad,
Índice de Severidad de la Enfermedad
Abstract Objectives: To study the microbiological pattern of late onset neonatal sepsis cultures and to assess the diagnostic performance of serum (1,3)-β-d-glucan level for early diagnosis of invasive fungemia in high-risk infants admitted to a neonatal intensive care unit. Methods: A prospective...
Chen, Xiao-tian;
Yang, Song;
Yang, Ya-ming;
Zhao, Hai-long;
Chen, Yan-chun;
Zhao, Xiang-hai;
Wen, Jin-bo;
Tian, Yuan-rui;
Yan, Wei-li;
Shen, Chong.
Abstract Objective: Total bilirubin is beneficial for protecting cardiovascular diseases in adults. The authors aimed to investigate the association of total bilirubin, red blood cell, and hemoglobin levels with the prevalence of high blood pressure in children and adolescents. Methods: A total of 3776...
ABSTRACT BACKGROUND: Hepatitis B and C are diseases with high morbimortality and constitute a global public health problem. In Brazil, the prevalence is not homogeneous, oscillating among different regions, but it is estimated that currently about 1% of the population present chronic disease related to...
Distribución por Edad,
Biomarcadores/sangre,
Brasil/epidemiología,
Estudios Transversales,
Hepatitis B/sangre,
Hepatitis B/epidemiología,
Anticuerpos contra la Hepatitis B/sangre,
Hepatitis C/sangre,
Hepatitis C/epidemiología,
Anticuerpos contra la Hepatitis C/sangre,
Hospitales Universitarios,
Persona de Mediana Edad,
Complicaciones Infecciosas del Embarazo/sangre,
Complicaciones Infecciosas del Embarazo/epidemiología,
Atención Prenatal/estadística & datos numéricos,
Prevalencia,
Estudios Retrospectivos,
Factores de Riesgo,
Estudios Seroepidemiológicos,
Estadísticas no Paramétricas,
Factores de Tiempo
ABSTRACT Objective: This cross-sectional study evaluated the association of plasma cytochrome c (CytoC) and hypoxia-inducible factor (HIF)-1α, as mitochondrial dysfunction and cellular hypoxia biomarkers, with disease risk factors and prognosis in Type 2 diabetic patients in Saudi Arabia. Methods:...
ABSTRACT Objective: It is proposed that in some conditions such as pregnancy and osteoporosis where the bone turnover rate is high, there is mobilization of various minerals including lead (Pb) from bone to blood. This study aimed to determine if there were any differences in serum Pb levels among elder...
ABSTRACT Objective: To observe the effect of thymosin alpha l (Tα1) on severe acute pancreatitis (SAP) in rats. Methods: Twenty-four adult male Sprague-Dawley rats were randomly divided into three groups (eight in each group): control group (Group A), SAP group (Group B) and Tα1 treatment gro...
Modelos Animales de Enfermedad,
Pancreatitis/tratamiento farmacológico,
Índice de Severidad de la Enfermedad,
Enfermedad Aguda,
Timalfasina/administración & dosificación,
Adyuvantes Inmunológicos/administración & dosificación,
Ratas Sprague-Dawley,
Biomarcadores/sangre,
Factor de Necrosis Tumoral alfa/sangre,
Interleucinas/sangre,
Amilasas/sangre
Las encefalitis autoinmunes son un nuevo grupo de enfermedades de gran trascendencia clínica y terapéutica debido a la buena respuesta en gran parte de los casos a la terapia inmunomoduladora indicada, con un gran porcentaje de curación, sin secuelas neurológicas importantes (cognitivo, motor, crisis...
Anticuerpos/sangre,
Autoanticuerpos/sangre,
Enfermedades Autoinmunes/diagnóstico,
Enfermedades Autoinmunes/tratamiento farmacológico,
Biomarcadores/sangre,
Encefalitis/diagnóstico,
Encefalitis/tratamiento farmacológico,
Enfermedad de Hashimoto/sangre,
Enfermedad de Hashimoto/diagnóstico,
Enfermedad de Hashimoto/tratamiento farmacológico,
Metilprednisolona/uso terapéutico,
Fármacos Neuroprotectores/uso terapéutico,
Rituximab/uso terapéutico
Abstract Objective: Melatonin has a protective role in adults with cardiovascular disease, but the effects of melatonin in children with cardiac dysfunction are not well understood. This study was designed to explore the variations in melatonin, myeloperoxidase, and caspase-3 levels in children sufferin...
ABSTRACT Objectives: Brucellosis is a multi-system infectious disease that is associated with inflammation, which causes an increase in acute phase reactants. Hematological inflammatory markers of brucellosis include mean platelet volume (MPV), red cell distribution width (RDW), neutrophil/lymphocyte ra...
Biomarcadores/sangre,
Brucelosis/sangre,
Brucelosis/diagnóstico,
Epididimitis/sangre,
Epididimitis/diagnóstico,
Epididimitis/microbiología,
Índices de Eritrocitos,
Modelos Logísticos,
Volúmen Plaquetario Medio,
Persona de Mediana Edad,
Neutrófilos,
Orquitis/sangre,
Orquitis/diagnóstico,
Orquitis/microbiología,
Recuento de Plaquetas,
Valores de Referencia,
Reproducibilidad de los Resultados,
Estudios Retrospectivos,
Medición de Riesgo,
Sensibilidad y Especificidad,
Estadísticas no Paramétricas,
Recuento de Leucocitos
