Rhabdomyolysis refers to the destruction or disintegration of striated muscles. This syndrome is characterized by muscle breakdown and necrosis, resulting in the leakage of intracellular muscle constituents into the circulation and extracellular fluid. We report a rare case of rhabdomyolysis complicating...
ABSTRACT Immunotherapy-induced pneumonitis is a rare complication with incidence estimated around 3%. This disease is difficult to diagnose and has great morbidity. For this reason, it became a challenge for oncologists and emergencists. We reviewed the case of five patients who used anti-PD1 (program ce...
Corticoesteroides/uso terapéutico,
Anticuerpos Monoclonales/efectos adversos,
Anticuerpos Monoclonales/uso terapéutico,
Anticuerpos Monoclonales Humanizados/efectos adversos,
Anticuerpos Monoclonales Humanizados/uso terapéutico,
Antineoplásicos/efectos adversos,
Antineoplásicos/uso terapéutico,
Carcinoma/terapia,
Resultado Fatal,
Inmunoterapia/efectos adversos,
Neoplasias Pulmonares/terapia,
Persona de Mediana Edad,
Nivolumab,
Neumonía/inducido químicamente,
Neumonía/diagnóstico por imagen,
Neumonía/tratamiento farmacológico
OBJECTIVES: To describe a case series of spontaneous pneumomediastinum in dermatomyositis and to review the literature. METHODS: This was a retrospective single-center case series, reporting 9 patients with pneumomediastinum and defined dermatomyositis, followed from 2005 to 2017. RESULTS: Median age o...
Estudios Retrospectivos,
Dermatomiositis/complicaciones,
Enfisema Mediastínico/etiología,
Enfermedades Raras,
Registros Electrónicos de Salud,
Dermatomiositis/tratamiento farmacológico,
Enfisema Mediastínico/tratamiento farmacológico,
Dermatomiositis/diagnóstico,
Enfisema Mediastínico/diagnóstico por imagen,
Creatina Quinasa/sangre,
Fructosa-Bifosfato Aldolasa/sangre,
Tomografía Computarizada por Rayos X,
Autoanticuerpos/sangre,
Disnea/etiología,
Enfermedades Pulmonares Intersticiales/complicaciones,
Glucocorticoides/uso terapéutico,
Quimioterapia por Pulso,
Metilprednisolona/administración & dosificación,
Inmunoglobulinas Intravenosas/uso terapéutico,
Inmunosupresores/uso terapéutico,
Resultado Fatal
Myasthenia gravis (MG) is a rare autoimmune disease of the neuromuscular junction. It is characterized by variable weakness and excessive fatigability of skeletal muscles. In the last few years, numerous reports have been published showing the association between autoimmune diseases, such as systemic ery...
Leucemia Linfocítica Crónica de Células B/complicaciones,
Linfoma de Células B Grandes Difuso/complicaciones,
Miastenia Gravis/complicaciones,
Plasmacitoma/complicaciones,
Amiloidosis/complicaciones,
Amiloidosis/patología,
Biopsia,
Inhibidores de la Colinesterasa/uso terapéutico,
Resultado Fatal,
Leucemia Linfocítica Crónica de Células B/patología,
Linfoma de Células B Grandes Difuso/patología,
Miastenia Gravis/tratamiento farmacológico,
Miastenia Gravis/patología,
Plasmacitoma/patología,
Bromuro de Piridostigmina/uso terapéutico
Abstract Stent-graft migration and type I endoleaks are associated with a higher rate of reintervention and increased mortality and morbidity. This article describes a patient presented with an infrarenal aortic stent-graft which had migrated into the aortic sac with loss of all aortic neck attachment. T...
Autopsia,
Cardiomiopatía Restrictiva/complicaciones,
Cardiomiopatía Restrictiva/diagnóstico,
Edema/complicaciones,
Edema/diagnóstico,
Resultado Fatal,
Pericarditis Constrictiva/complicaciones,
Pericarditis Constrictiva/diagnóstico,
Enfermedades Pleurales/complicaciones,
Enfermedades Pleurales/diagnóstico,
Derrame Pleural
Resumen Introducción: La asociación Mardini-Nyhan o LACHT es una condición clínica de baja prevalência que cursa con alteraciones pulmonares, cardíacas y de las extremidades. Su etiología no está clara mente documentada hasta la fecha. Objetivo: Describir el caso de una niña de 4 meses y reali...
High-grade B-cell lymphomas with rearrangement of MYC, BCL-2 and/or BCL-6 were introduced by the update of the WHO classification of lymphoid neoplasms. They usually present unique morphological and molecular characteristics, with an aggressive clinical outcome and worse prognosis. We report a 48 year-ol...
Abstract The clinical management and decision-making in pregnancies in which there is suspicion of lethal fetal malformations during the prenatal period, such as lethal skeletal dysplasia (SD), demand a multidisciplinary approach coordinated by an experienced physician. Based on the presentation of a cas...
Resumen: Introducción: La leucoencefalopatía con sustancia blanca evanescente es una de las leucodistrofias más frecuentes. Generalmente inicia en la infancia y presenta un patrón de herencia autosómica recesiva. El 90% de los casos manifiesta mutaciones en uno de los genes que codifican para las ...