Introduction: Staphylococcus aureus and Escherichia coli are pathogens that cause chronic infections due to antibiotic resistance mechanisms and their ability to adhere to surfaces and to form biofilms. The search for new agents from natural resources to counter microbial biofilms is an urgent priority i...
Introdução: as terapias alternativas que utilizam plantas medicinais e fitoterápicos são bastante comuns no Brasil. Dentre várias espécies vegetais brasileiras utilizadas em terapias destacam-se as espécies da família Malvaceae. Objetivos: o presente estudo teve como objetivo avaliar a citotoxici...
This paper describes the evaluation of the antimicrobial and hemolytic activity of the hexane, dichloromethane, ethyl acetate and methanol extracts from seeds and epicarps of Garcinia madruno; as well garcinol, morelloflavone and volkensiflavone isolated from the same species. In the preliminary test of...
Copaifera spp. essential oil (EOC) was extracted by hydrodistillation of Copaifera oleoresin (COR). The EOC was characterized by GC/MS and a novel EOC-loaded nanoemulsion was developed to enhance the EOC solubility and to evaluate its utility as antinflammatory. EOC contain 14 volatile compounds (includ...
Fabaceae/química,
Aceites Volátiles/farmacología,
Aceites Volátiles/química,
Antiinflamatorios/farmacología,
Emulsiones/farmacología,
Nanopartículas,
Cromatografía de Gases y Espectrometría de Masas,
Sesquiterpenos Policíclicos/análisis,
Tensoactivos,
Temperatura,
Concentración de Iones de Hidrógeno,
Reología,
Pruebas de Toxicidad Aguda
Leaf and fruit decoctions of Schinus areira L. from northwest Argentina were investigated here. Phenolic compounds and organic acids were analyzed by HPLC. Antioxidant capacity and α-glucosidase inhibition were determined by using in vitro tests. The general toxicity was assessed against Artemia salina...
Raza, Syed Ali;
Rashid Ch, Ayoub;
Mumtaz, Muhammad Waseem;
Bashir, Sadia;
Ahmad, Maqsood;
Touqeer, Tooba;
Mukhtar, Hamid;
Akhtar, Muhammad Tayyab;
Ali, Sajed;
William, James.
The antioxidant activity and the inhibitory potential of α-amylase of lyophilized hydroethanolic extracts of Conocarpus erectus leaves obtained by ultrasonication were determined. The most potent extract was subjected to ultra-high performance liquid chromatography system equipped with mass spectromet...
This study evaluated the specific interactions between drug and polymers in amorphous spray dried dispersions (SDDs). Four Biopharmaceutics Classification System (BCS) II class drugs were evaluated. Binary and ternary SDDs were manufactured with conventional polymers and arabinogalactan. Specific intera...
The objective of the work was to study the cytotoxic effect of ent-kaurene acid derivatives obtained from Coespeletia moritziana (Sch. Bip. Ex Wedd.) Cuatrec., After analysis by GC/MS, IR and NMR. Isolating: kaurenic acid (I), grandifloric acid (II), 15-α-hydroxy kaurenic acid (III), 15 α-acetoxy-kaur ...
Asteraceae/química,
Extractos Vegetales/química,
Línea Celular Tumoral/efectos de los fármacos,
Extractos Vegetales/farmacología,
Diterpenos/aislamiento & purificación,
Diterpenos/farmacología,
Cromatografía de Gases y Espectrometría de Masas,
Cromatografía en Capa Delgada,
Espectrofotometría Infrarroja,
Imagen por Resonancia Magnética,
Diterpenos de Tipo Kaurano
La cantidad de fluoruros en el agua en algunas regiones de México representa un problema de salud pública. El objetivo de este trabajo fue realizar una revisión sistemática de estudios originales que reportaran niveles de fluoruros en agua corriente y embotellada de la región norte y occidente de M...
RESUMEN Objetivo: Determinar los biomarcadores inflamatorios del líquido sinovial (LS) de pacientes adultos con trastornos intraarticulares (TI) de la articulación temporomandibular (ATM) y su capacidad diagnóstica. Métodos: Se realizó búsqueda electrónica/manual de artículos (2010-2019) en paral...
