El síndrome de Pallister-Killian es una entidad poco frecuente causada por tetrasomía 12p en mosaico. Presenta facies tosca, alopecia frontotemporal, frente prominente, fisuras palpebrales oblicuas ascendentes, hipertelorismo ocular, ptosis palpebral, estrabismo, epicanto, puente nasal ancho, nariz cor...
Abstract INTRODUCTION. This study aimed to evaluate different methods for differentiation of species of coagulase-negative staphylococci (CoNS) that caused infections in hospitalized immunocompromised patients. METHODS. A total of 134 CoNS strains were characterized using four different methods. RES...
Abstract INTRODUCTION: Here, we determined the genes encoding antibiotic resistance enzymes and virulence factors and evaluated the genetic relationship between Enterobacter spp. isolated from different clinical samples. METHODS: A total of 57 clinical isolates of Enterobacter spp. were tested for th...
Antibacterianos/farmacología,
Proteínas Bacterianas/biosíntesis,
Proteínas Bacterianas/efectos de los fármacos,
Proteínas Bacterianas/genética,
Células Clonales,
Pruebas Antimicrobianas de Difusión por Disco,
Farmacorresistencia Bacteriana Múltiple,
Escherichia coli/efectos de los fármacos,
Escherichia coli/enzimología,
Escherichia coli/genética,
Heces/microbiología,
Genotipo,
Irán,
Fenotipo,
Reacción en Cadena de la Polimerasa,
beta-Lactamasas/biosíntesis,
beta-Lactamas/efectos adversos,
beta-Lactamasas/genética
ABSTRACT Background: The dual potential to promote tolerance or inflammation when facing self-antigens makes dendritic cells (DCs) fundamental players in autoimmunity. There is an association between smoking and DCs maturation in patients with rheumatoid arthritis (RA). However, ethnicity is a key facto...
Artritis Reumatoide/metabolismo,
Proliferación Celular/fisiología,
Células Dendríticas/inmunología,
Fumar/efectos adversos,
Antígenos de Diferenciación de Linfocitos B/inmunología,
Artritis Reumatoide/inmunología,
Artritis Reumatoide/fisiopatología,
Estudios de Casos y Controles,
Chile,
Progresión de la Enfermedad,
Citometría de Flujo,
Antígenos HLA-DR/inmunología,
Inflamación/tratamiento farmacológico,
Inflamación/fisiopatología,
Fenotipo,
Fumar/fisiopatología,
Subgrupos de Linfocitos T/inmunología
Abstract Background: Familial hypercholesterolemia (FH) is a common autosomal dominant disorder, characterized by a high level of low-density lipoprotein cholesterol (LDL-C) and a high risk of premature cardiovascular disease. Objective: To evaluate clinical and anthropometric characteristics of patien...
Cordeiro, Rossana A;
Sales, Jamille A;
Ponte, Yago B. de;
Mendes, Patrícia B. L;
Serpa, Rosana;
Evangelista, Antônio J;
Alencar, Lucas P. de;
Pereira-Neto, Waldemiro de A;
Brilhante, Raimunda S. N;
Sidrim, José J. C;
Castelo-Branco, Débora S. C. M;
Rocha, Marcos F. G.
Abstract In this study, phenotypic methods presented >80% agreement with the molecular identification of 59 Candida parapsilosis complex. Growth at 15% NaCl or pH 7.0 significantly reduced cfu-counts of Candida orthopsilosis, suggesting these conditions may support the development of phenotypic method...
O adenocarcinoma gástrico (AdG) é a terceira causa mais comum de morte por câncer no mundo e um dos tumores com maior índice de mortalidade no Brasil. Estes tumores aparecem em terceiro lugar na incidência entre homens e em quinto nas mulheres. A quimioterapia neoadjuvante (QT) com 5-fluorouracil (5...
Human pluripotent stem cells (hPSCs)/OP9 coculture system is a widely used hematopoietic differentiation approach. The limited understanding of this process leads to its low efficiency. Thus, we used single-cell qPCR to reveal the gene expression profiles of individual CD34+ cells from different stages o...
