OBJECTIVE: The aim of this study was to evaluate the protective and therapeutic effects of quercetin on pancreatic injury in cerulein-induced acute pancreatitis. METHOD: Thirty-two rats were randomly divided into four groups, eight per group: (CT): untreated controls, (CER) treated with cerulein, 50 µ...
Abstract Objective: To test the efficacy of Acetylcholine chloride use in obtaining intraoperative miosis on phacoemulsification cataract surgery. Methods: Patients with cataract diagnosis and elected for surgical phacoemulsification procedure were selected. All patients underwent conventional phacoemu...
Miosis/inducido químicamente,
Mióticos/administración & dosificación,
Mióticos/farmacología,
Acetilcolina/administración & dosificación,
Acetilcolina/farmacología,
Cámara Anterior/efectos de los fármacos,
Pupila/efectos de los fármacos,
Facoemulsificación/métodos,
Lentes Intraoculares,
Implantación de Lentes Intraoculares/métodos,
Cuidados Intraoperatorios,
Irrigación Terapéutica/métodos
Antibacterianos/farmacología,
Antibacterianos/uso terapéutico,
Compuestos de Azabiciclo/farmacología,
Brasil,
Ceftazidima/farmacología,
Combinación de Medicamentos,
Farmacorresistencia Bacteriana/efectos de los fármacos,
Bacterias Gramnegativas/efectos de los fármacos,
Bacterias Gramnegativas/aislamiento & purificación,
Infecciones por Bacterias Gramnegativas/tratamiento farmacológico,
Hospitales de Enseñanza,
Pruebas de Sensibilidad Microbiana
OBJECTIVES: Tissue adhesives can be used to prevent pulmonary air leaks, which frequently occur after lung interventions. The objective of this study is to evaluate local and systemic effects of fibrin and cyanoacrylate tissue adhesives on lung lesions in rabbits. METHODS: Eighteen rabbits were submitte...
Cianoacrilatos/uso terapéutico,
Ensayo de Inmunoadsorción Enzimática,
Adhesivo de Tejido de Fibrina/uso terapéutico,
Hemodinámica,
Interleucina-8/sangre,
Recuento de Leucocitos,
Pulmón/efectos de los fármacos,
Pulmón/patología,
Lesión Pulmonar/tratamiento farmacológico,
Distribución Aleatoria,
Valores de Referencia,
Reproducibilidad de los Resultados,
Toracoscopía/métodos,
Factores de Tiempo,
Adhesivos Tisulares/uso terapéutico,
Resultado del Tratamiento
Artemisia genus (family Asteraceae) has been widely used as medicines and cosmetic. The chemical compositions of essential oils extracted from five Artemisia species (A. anethoides, A. giraldii, A. roxburghiana, A. rubripes and A. sacrorum) were analyzed and the repellent activities of five essential oil...
Artemisia/química,
Asteraceae/química,
Aceites Volátiles/farmacología,
Aceites Volátiles/química,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Tribolium/efectos de los fármacos,
Escarabajos/efectos de los fármacos,
Terpenos/análisis,
Repelentes de Insectos/farmacología,
Cromatografía de Gases y Espectrometría de Masas
The flavonoid 3,5-dihydroxy-7-methoxyflavanone ((-)-alpinone) isolated from sticky resinous exudate of Heliotropium huascoense was evaluated as immunostimulatory in mammalian cells . Preliminary observations had showed that (-)-alpinone had increased the expression levels of pro-inflammatory cytokine tra...
Abstract Purpose: To evaluate the ability of dexamethasone to protect against cisplatin (CDDP)-induced ototoxicity. Methods: Male Wistar rats were divided into the following three groups: 1) Control (C): 6 animals received intraperitoneal (IP) saline solution, 8 ml/kg/day for four days; 2) C + CDDP: ...
Abstract Purpose: To evaluate the use of platelet-rich plasma in the early stages of healing of traumatic injury of the medial collateral ligament in the knee of rabbits. Methods: Thirty rabbits were subjected to surgical lesion of the medial collateral ligament. Of these, 16 were treated with platel...
Abstract Purpose: To investigate whether the neuroprotective effect of TSA on cerebral ischemia reperfusion injury is mediated by the activation of Akt/GSK-3β signaling pathway. Methods: Mice were randomly divided into four groups (n=15): sham group (S); ischemia reperfusion group (IR); ischemia...
Modelos Animales de Enfermedad,
Glucógeno Sintasa Quinasa 3/efectos de los fármacos,
Glucógeno Sintasa Quinasa 3/metabolismo,
Inhibidores de Histona Desacetilasas/farmacología,
Ataque Isquémico Transitorio/metabolismo,
Ataque Isquémico Transitorio/fisiopatología,
Ratones Endogámicos BALB C,
Fármacos Neuroprotectores/farmacología,
Proteínas Proto-Oncogénicas c-akt/efectos de los fármacos,
Transducción de Señal/efectos de los fármacos,
Transducción de Señal/fisiología
Abstract Objectives: To correlate the basal expression of complement regulatory proteins (CRPs) CD55, CD59, CD35, and CD46 in B-lymphocytes from the peripheral blood of a cohort of 10 patients with rheumatoid arthritis (RA) initiating treatment with rituximab (RTX) with depletion and time repopulation o...
Antirreumáticos/farmacología,
Antirreumáticos/uso terapéutico,
Artritis Reumatoide/sangre,
Artritis Reumatoide/tratamiento farmacológico,
Artritis Reumatoide/inmunología,
Linfocitos B/efectos de los fármacos,
Linfocitos B/metabolismo,
Biomarcadores/sangre,
Esquema de Medicación,
Proteínas Ligadas a GPI/sangre,
Infusiones Intravenosas,
Persona de Mediana Edad,
Rituximab/farmacología,
Rituximab/uso terapéutico,
Resultado del Tratamiento
