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Genetic polymorphisms of glutathione s-transferase mu1 and theta1 in patients with acquired aplastic anemia: a Brazilian experience

Vicari, Perla; Duch, Cibele R; Shimmoto, Marily M. A; Noguti, Maria Aparecida E; Figueiredo, Maria Stella.
Rev. bras. hematol. hemoter; 29 (4), 2007
The causes of acquired aplastic anemia (AAA) include immunologic mechanisms and oxidative DNA damage. Glutathione S-transferase (GST) plays an important role in detoxification. In humans, GST genes encode four main clones: alpha (A), mu (M), pi (P) and theta (T). Among GST genes, GST M1 and T1 have null ...
Glutatión, Anemia Aplásica, Polimorfismo Genético, Genes, Genotipo, ADN, Estrés Oxidativo, Enzimas, Gutatión-S-Transferasa pi
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Polimorfismo do gene tp53 no códon 72 em pacientes com suspeita de LMC
Codon 72 polymorphism of the TP53 gene in patients suspected to have CML

Hamú, Camila S; Oliveira, Marcus Vinícius P; Silva, Antonio Márcio T. C; Silva, Cláudio Carlos; Cruz, Aparecido Divino.
Rev. bras. hematol. hemoter; 29 (4), 2007
A leucemia mielóide crônica (LMC) é uma doença proliferativa do sistema hematopoiético, caracterizada pela expansão clonal de uma célula-tronco primitiva e pluripotente denominada stem cell. Este tipo de leucemia está associado, em 90 por cento dos casos, à translocação t(9;22)(q34;q11). Essa ...
Genes p53, Leucemia Mielógena Crónica BCR-ABL Positiva, Leucemia, Factores de Riesgo, Frecuencia de los Genes, Mutación, Neoplasias, Polimorfismo Genético, Reacción en Cadena de la Polimerasa, Sistema Hematopoyético, Translocación Genética, Homocigoto, Genotipo, Daño del ADN, Células Madre Pluripotentes, Apoptosis, Arginina, Células, ADN
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A Common 34C>G Variant at the Peroxisome Proliferator-Activated Receptor gamma Gene in Chilean Women with Polycystic Ovary Syndrome and Controls

Guzmán, Neftalí; Erices, Leonardo; Valdés, Patricio; Salazar, Luis A.
Int. j. morphol; 25 (4), 2007
The 34C>G (Prol2Ala) polymorphic variant of the peroxisome proliferator-activated receptor-γ2 (PPAR-γ2) gene has been associated with polycystic ovary syndrome (PCOS). However, the results between populations are contradictory. Thus, in the present study was investigated the possible associatio...
Síndrome del Ovario Poliquístico/genética, PPAR gamma/genética, Chile, Reacción en Cadena de la Polimerasa/métodos, Polimorfismo de Longitud del Fragmento de Restricción, ADN/análisis, Genotipo, Lípidos/sangre, Glucemia/análisis, Ácido Úrico/sangre, Colorimetría
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DNA flow cytometry of canine mammary tumors: comparative aspects with human breast tumors

Cassali, G. D; Salvador, A; Freitas, C; Dutra, A. P; Schmitt, F. C.
Arq. bras. med. vet. zootec; 59 (5), 2007
Flow cytometric analysis of DNA content was performed on 28 samples of canine mammary tumors. Nine of them were benign and 19 were malignant. All benign tumors and 11 malignant tumors (57.9 percent) were diploid (P<0.05). Form the aneuploid tumors, five (26.3 percent) were hyperdiploid, one (5.3 percent)...
Inmunohistoquímica, Inmunohistoquímica, ADN
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