Abstract Reports have indicated that serotonin plays an important role in cell migration and differentiation during the organogenesis of several tissues, including the oral types. Administration of selective serotonin reuptake inhibitor (SSRI) drugs during pregnancy could affect the delivery of serotonin...
Proceso Alveolar/efectos de los fármacos,
Proceso Alveolar/embriología,
Colágenos Fibrilares/análisis,
Fluoxetina/farmacología,
Inmunohistoquímica,
Lactancia,
Exposición Materna,
Osteogénesis/efectos de los fármacos,
Ligamento Periodontal/efectos de los fármacos,
Ligamento Periodontal/embriología,
Ligamento Periodontal/crecimiento & desarrollo,
Distribución Aleatoria,
Ratas Wistar,
Inhibidores Selectivos de la Recaptación de Serotonina/farmacología,
Factores de Tiempo
Abstract Objective To prepare nanocomposite cements based on the incorporation of bioactive glass nanoparticles (nBGs) into BiodentineTM (BD, Septodent, Saint-Maur-des-Fosses Cedex, France) and to assess their bioactive properties. Material and Methods nBGs were synthesised by the sol-gel method. BD ...
Apatitas/química,
Compuestos de Calcio/química,
Dentina/efectos de los fármacos,
Cementos de Ionómero Vítreo/química,
Inmersión,
Ensayo de Materiales,
Microscopía Electrónica de Rastreo,
Nanopartículas/química,
Reproducibilidad de los Resultados,
Cementos de Resina/química,
Silicatos/química,
Espectrometría por Rayos X,
Espectroscopía Infrarroja por Transformada de Fourier,
Estadísticas no Paramétricas,
Propiedades de Superficie/efectos de los fármacos,
Factores de Tiempo,
Difracción de Rayos X
Abstract The effects of the non-steroidal anti-inflammatory drugs (NSAIDs) on bone quantity and quality were investigated for years. However, there is lack of information on the impact of NSAIDs on the quality of tooth-supporting alveolar bone in absence of periodontal inflammation. Thus, the aim of this...
The aim of the study was to evaluate dentinal tubule occlusion, measuring the dentin permeability (Lp) and using different desensitizing agents before and after abrasive/erosive challenge. Dentin discs from 42 healthy human third molars were obtained. Minimum Lp was measured after a smear layer simulatio...
Abstract This study evaluated the action of ionizing radiation and the possible radioprotective effect of the non-steroidal anti-inflammatory drug meloxicam on the bone physiology of rat mandibles by assessing the alveolar socket healing and bone strength. Forty male Wistar rats were divided in 4 groups ...
Abstract Evaluating the addition of minimum inhibitory concentrations (MICs) of antifungals for Candida albicans biofilm on the hardness and roughness of temporary denture soft liners. Specimens (n=8; 36×7×6 mm) of tissue conditioner (Softone) and resilient liner (Trusoft) were produced either without ...
Estudios han demostrado que el aceite de oliva (O) con sus compuestos fenólicos tienen efectos positivos en diversos biomarcadores fisiológicos. Análisis previos han demostrado que los bisfosfonatos, son potentes inhibidores de la resorción ósea. Estudiar el efecto del tratamiento combinado de alend...
The aim of this in vitro study was to assess the root dentin demineralization caused by a microcosm biofilm model that has been exposed to sucrose in different ways. Materials and Methods: Saliva of two volunteers was inoculated into an artificial medium for biofilm growth and dentin blocks were immersed...
Spirlandeli, Adriano L;
Dick-de-Paula, Ingrid;
Zamarioli, Ariane;
Jorgetti, Vanda;
Ramalho, Leandra NZ;
Nogueira-Barbosa, Marcello H;
Volpon, Jose B;
Jordão, Alceu A;
Cunha, Fernando Q;
Fukada, Sandra Y;
de Paula, Francisco JA.
OBJECTIVES: The present study was designed to evaluate the bone phenotypes and mechanisms involved in bone disorders associated with hepatic osteodystrophy. Hepatocellular disease was induced by carbon tetrachloride (CCl4). In addition, the effects of disodium pamidronate on bone tissue were evaluated. ...
Conservadores de la Densidad Ósea/farmacología,
Enfermedades Óseas Metabólicas/tratamiento farmacológico,
Enfermedades Óseas Metabólicas/etiología,
Enfermedades Óseas Metabólicas/metabolismo,
Remodelación Ósea/efectos de los fármacos,
Resorción Ósea/metabolismo,
Huesos/diagnóstico por imagen,
Huesos/efectos de los fármacos,
Huesos/metabolismo,
Tetracloruro de Carbono,
Subunidad alfa 1 del Factor de Unión al Sitio Principal/genética,
Difosfonatos/farmacología,
Modelos Animales de Enfermedad,
Cirrosis Hepática/inducido químicamente,
Cirrosis Hepática/metabolismo,
Hepatopatías/complicaciones,
Hepatopatías/metabolismo,
Ratones Endogámicos C57BL,
Osteoprotegerina/genética,
Fósforo/administración & dosificación,
Ligando RANK/genética,
Fosfatasa Ácida Tartratorresistente/genética,
Microtomografía por Rayos X
ABSTRACT Purpose: To investigate the effect of nicotinamide on the secretion of pro-an giogenic and pro-inflammatory cytokines in uveal melanoma cell lines. Methods: Two human uveal melanoma cell lines (92.1 and OCM-1) were treated with nicotinamide (10 mmol/L) or control media for 48 hours in culture....
Inhibidores de la Angiogénesis/farmacología,
Angiopoyetina 2/metabolismo,
Antiinflamatorios/farmacología,
Línea Celular Tumoral,
Quimiocina CCL2/efectos de los fármacos,
Citocinas/efectos de los fármacos,
Factor de Crecimiento Epidérmico/efectos de los fármacos,
Citocinas/metabolismo,
Factor 2 de Crecimiento de Fibroblastos/efectos de los fármacos,
Interleucina-8/efectos de los fármacos,
Melanoma/irrigación sanguínea,
Melanoma/metabolismo,
Niacinamida/farmacología,
Factor de Crecimiento Placentario/efectos de los fármacos,
Ribonucleasa Pancreática/efectos de los fármacos,
Neoplasias de la Úvea/irrigación sanguínea,
Neoplasias de la Úvea/metabolismo
