Background: Ascorbic acid (Asc) is one of the most abundant antioxidants and it serves as a major contributor to protect plants against oxidative damage. Plants use two enzymes that participate in the metabolic recycling of Asc. One of these two enzymes is dehydroascorbate reductase (DHAR). It directly r...
Oxidorreductasas/metabolismo,
Nicotiana/enzimología,
Estrés Oxidativo,
Plantas Modificadas Genéticamente/enzimología,
Ácido Ascórbico/administración & dosificación,
Antioxidantes/administración & dosificación,
Nicotiana/efectos de los fármacos,
Plantas Modificadas Genéticamente/efectos de los fármacos,
Oxidorreductasas/genética,
Ácido Ascórbico/metabolismo,
Antioxidantes/metabolismo,
Oxidorreductasas/aislamiento & purificación,
Western Blotting,
Especies Reactivas de Oxígeno,
Tolerancia a la Sal,
Estrés Fisiológico,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa
Abstract Purpose: To evaluate the inflammatory intensity and measure the tissue content of the proteins claudin-3 and occludin in the colonic mucosa without fecal stream submit to intervention with curcumin. Methods: Thirty-six rats were submitted to a proximal colostomy and a distal mucous fistula and...
Claudina-3/análisis,
Colon/química,
Curcuma/química,
Enema/métodos,
Mucosa Intestinal/química,
Ocludina/análisis,
Aceites de Plantas/farmacología,
Colon/efectos de los fármacos,
Colon/patología,
Colostomía,
Heces,
Inmunohistoquímica,
Mucosa Intestinal/efectos de los fármacos,
Mucosa Intestinal/patología,
Ratas Wistar
Abstract Purpose: To evaluate the effect of oxacillin bonded to magnetic nanoparticles in local infection model in rat. Methods: Twelve Wistar rats weighing 290±18g were randomly divided into four groups (n=6, each) and all rats had a magnet ring sutured on their right thighs. In the biodistribution g...
García, Apolinaria;
Navarro, Karen;
Sanhueza, Enrique;
Pineda, Susana;
Pastene, Edgar;
Quezada, Manuel;
Henríquez, Karem;
Karlyshev, Andrey;
Villena, Julio;
González, Carlos.
Background: Helicobacter pylori is considered as the main risk factor in the development of gastric cancer. In the present study, we performed a detailed characterization of the probiotic properties and the anti-H. pylori activity of a previously isolated lactobacillus strain — Lactobacillus fermentum ...
Neoplasias Gástricas/prevención & control,
Infecciones por Helicobacter/prevención & control,
Helicobacter pylori/efectos de los fármacos,
Limosilactobacillus fermentum/fisiología,
Probióticos/farmacología,
Gerbillinae,
Interacciones Hidrofóbicas e Hidrofílicas,
Ureasa/antagonistas & inhibidores,
Antibacterianos/farmacología,
Modelos Animales de Enfermedad,
Interleucina-8/antagonistas & inhibidores
Gomes, Mariana Teixeira;
Campos, Gabriela Russo Soeiro;
Piccolo, Natália;
França, Cristiane Miranda;
Guedes, Guelton Hirano;
Lopes, Fabio;
Belotto, Renata A;
Pavani, Christiane;
Lima, Rafael do Nascimento de;
Silva, Daniela de Fátima Teixeira da.
Summary Objective: To analyze morphological characteristics and organization of the collagen fibers of third degree burns from scalding compared to laser therapy and silver sulfadiazine, the latter considered as the gold standard. Method: Were selected 12 animals (Rattus norvegicus) also divided into t...
Sepse é uma resposta sistêmica e deletéria do indivíduo a uma infecção, sendo um importante problema de saúde pública. Pacientes diabéticos são bastante afetados representando cerca de 22% de todos os pacientes sépticos. A suscetibilidade para o desenvolvimento de sepse no diabetes, bem como a...
The focus of our studies has been the root substrate dentin, once root caries
prevalence has been reported as increasing in part due to people living longer and
maintaining their natural teeth into old age. Furthermore, this condition is highly
prevalent in patients undergoing head-and-neck radiotherapy ...
Os bisfosfonatos (BF) são amplamente utilizados no tratamento de doenças osteolíticas como metástases ósseas e osteoporose. A osteonecrose dos maxilares associada ao uso de BF (OMAB) é caracterizada pela presença de osso exposto ou que pode ser sondado através de uma fístula que persiste por mai...
Osteonecrosis de los Maxilares Asociada a Difosfonatos/tratamiento farmacológico,
Difosfonatos/administración & dosificación,
Imidazoles/administración & dosificación,
Conservadores de la Densidad Ósea/administración & dosificación,
Enfermedades Mandibulares/tratamiento farmacológico,
Hueso Esponjoso/efectos de los fármacos,
Fémur/efectos de los fármacos,
Factores de Tiempo,
Osteonecrosis de los Maxilares Asociada a Difosfonatos/fisiopatología,
Microtomografía por Rayos X,
Densidad Ósea,
Resultado del Tratamiento,
Reproducibilidad de los Resultados,
Distribución Aleatoria,
Ratas Wistar
The adhesive process to dentin substrate depends on the condition determined
by the combined action of the mineral loss and the endogenous enzymes activity.
Thus, considering a more complete therapeutic approach, sodium trimetaphosphate
(STMP) may be a novel strategy that conciliates the remineralization...
This study aimed to answer the following questions: 1) does whole fluoridated milk protect
more against enamel and dentin erosion than fat-free fluoridated milk? 2) does the protective
effect of fluoridated milk against erosion follow a dose-response relationship? 3) is the
treatment with whole or fat-fr...
Leche/química,
Sustancias Protectoras/química,
Desmineralización Dental/prevención & control,
Fluoruros/química,
Cariostáticos/química,
Dentina/efectos de los fármacos,
Esmalte Dental/efectos de los fármacos,
Factores de Tiempo,
Proteómica,
Proteínas/análisis,
Reproducibilidad de los Resultados
