Results: 428

Mesilato de rasagilina em combinação com levodopa para o tratamento de pacientes com doença de Parkinson com complicações motoras

CONTEXTO: a doença de Parkinson (DP) tem distribuição universal e atinge a todos os grupos étnicos e classes socioeconômicas, com uma discreta predominância no sexo masculino. É a segunda desordem neurodegenerativa mais frequente, estando atrás apenas da doença de Alzheimer (1). A prevalência e...

Different outcomes of phonemic verbal fluency in Parkinson's disease patients with subthalamic nucleus deep brain stimulation

Arq. neuropsiquiatr; 75 (4), 2017
ABSTRACT Subthalamic nucleus deep brain stimulation (STN-DBS) is a surgical technique to treat motor symptoms in patients with Parkinson’s disease (PD). Studies have shown that STN-DBS may cause a decline in verbal fluency performance. We aimed to verify the effects of STN-DBS on the performance of...

PET/MRI: a novel hybrid imaging technique. Major clinical indications and preliminary experience in Brazil

Einstein (Säo Paulo); 15 (1), 2017
ABSTRACT In recent years, medical imaging with hybrid techniques has widely accepted and employed in clinical routine. PET/MRI offers significant advantages, including excellent contrast and resolution and reduced ionizing radiation, as compared to well-established PET/CT. Therefore, PET/MRI is a promisi...

Parkinson's disease - 200 years: the outstanding contribution of "Old Hubert"

Arq. neuropsiquiatr; 75 (3), 2017
ABSTRACT Two hundred years after the publication, of “An Essay on the Shaking Palsy”, this indisputable landmark in our understanding of the nature of Parkinson’s disease still remains. What is frequently overlooked, however, is the originality of James Parkinson’s ideas about how...

Guía de práctica clínica para el diagnóstico y tratamiento del trastorno neurocognoscitivo mayor (demencia) (adopción): para profesionales de la salud

La guía está orientada a la valoración y tratamiento de personas con demencia en los escenarios de la comunidad, cuidado en asilo y hospitales. Reconociendo el rol vital de los cuidadores y las familias que proporcionan cuidado a las personas con demencia, también se dan recomendaciones respecto al a...

Adesão de médicos prescritores ao protocolo clínico e diretrizes terapêuticas para doença de Parkinson

Introdução: Protocolos Clínicos e Diretrizes Terapêuticas (PCDT) são tecnologias em saúde que estabelecem as linhas de cuidado por agravo, no âmbito do Sistema Único de Saúde. Apesar de a utilização de diretrizes clínicas impactar positivamente nos desfechos em saúde, há pouco conhecimento ...

Intranasal mucoadhesivemicroemulsion for neuroprotective effect of curcuminin mptp induced Parkinson model

ABSTRACT This study was to investigate the neuroprotective effect of curcumin against inflammation-mediated dopaminergic neurodegeneration in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mice model of Parkinson's disease (PD). Curcumin loaded sodium hyaluronate based mucoadhesive microemulsion (CM...

Treadmill in Parkinson's: influence on gait, balance, BDNF and Reduced Glutathione

Fisioter. Mov. (Online); 30 (supl.1), 2017
Abstract Introduction: Parkinson's disease (PD) is characterized by nigrostriatal degeneration, with dopaminergic depletion, and inflammatory and oxidative changes in the brain, leading to movement and coordination disorders. Recent studies have shown that treadmill training can be beneficial for these ...

Nintendo Wii training on postural balance and mobility rehabilitation of adults with Parkinson's disease: a systematic review

Fisioter. Mov. (Online); 30 (supl.1), 2017
Abstract Introduction: Postural instability affects balance control in Parkinson disease (PD) patients and increases the particular risk of falling compared with healthy older adults. Video games with not immersive virtual reality have been used in neurological disorders rehabilitation process. Objecti...